SARS-CoV-2 Proteins and Their Target Proteins

SARS-CoV-2 Proteins and Their Target Proteins

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SARS-CoV-2 Proteins and Their Target Proteins

The COVID-19 outbreak has caused large numbers of death, as well as social and economic chaos worldwide. SARS-CoV-2 virus is the causative agent of this respiratory disease.

The scientific community has known that SARS-CoV-2 binds to host cell receptors through its surface spike (S) proteins and is endocytosed into cells through clathrin-mediated membrane fusion. The relationship and affinity between the host cell receptor and the virus surface protein determine the infectivity and cytophilic characteristics of the virus. The pathogenicity and invading of the virus are related to the type and function of the host cell. Crystal structure analysis confirmed that angiotensin-converting enzyme 2 (ACE2) is the receptor for SARS-CoV-2 S protein, and the affinity of the two is 10-20 times that of SARS-CoV and ACE2, which is the reason of SARS-CoV-2 super infectivity.

So far, no clinically available antiviral drugs have been developed for SARS-CoV, SARS-CoV-2, or MERS-CoV. Some studies used affinity purification-mass spectrometry analysis that have identified hundreds of protein interactions between SARS-CoV-2 proteins and human proteins, including DNA replication (Nsp1), epigenetic and gene expression regulators (Nsp5, Nsp8, Nsp13, E), vesicle trafficking (Nsp6, Nsp7, Nsp10, Nsp13, Nsp15, Orf3a, E, Orf8), lipid modification (Spike), RNA processing and regulation (Nsp8, N), ubiquitin ligases (Orf10), signaling (Nsp8, Nsp13, N, Orf9b), nuclear transport machinery (Nsp9, Nsp15, Orf6), cytoskeleton (Nsp1, Nsp13), mitochondria (Nsp4, Nsp8, Orf9c), and extracellular matrix (Nsp9). Results from data analysis suggested that the viral proteins connect to a wide array of biological processes, including protein trafficking, translation, transcription, and ubiquitination regulation.

A total of 332 high confidence SARS-CoV-2-human protein-protein interactions (PPIs) have been identified. Among these, using a combination of a systematic chemoinformatic drug search with a pathway centric analysis, researchers have uncovered 66 druggable human proteins or host factors targeted by close to 70 different drugs and compounds, including FD A approved drugs, compounds in clinical trials as well as preclinical compounds. Additionally, this proteomic/chemoinformatic analysis gives these potential therapeutic perturbations a mechanistic context.

Creative BioMart has collected many SARS-CoV-2 related proteins and druggable target proteins, which can help you discover antiviral therapies against SARS-CoV-2 and other deadly coronavirus strains.

For more protein product information or custom protein expression service, please feel free to contact us.

Recently, South Africa has detected a new mutant of the Sars-CoV-2-B.1.1.529. The World Health Organization (WHO) included B.1.1.529 on the Variant of Concern (VOC), named Omicron.

B.1.1.529 contains at least 50 mutations, 30 of which are on the spike protein (S protein). Not surprisingly, spike protein has become the research and development target of most vaccines. Some of the mutations are known to affect infectivity and immune escape, while others are newly identified. It is currently unknown what will happen when these mutations combine and their effects on the Sars-CoV-2 vaccine.

Creative BioMart is still committed to overcoming the challenges posed by the COVID-19 pandemic. We have just added a new panel of mutant RBD/spike and nucleocapsid proteins. In addition to the Omicron variant, Creative BioMart also provides other COVID variants (Alpha, Beta, Gamma, Delta, Eta, Iota, Kappa, and Lambda). We will continue to update our catalog to include new mutant proteins. Please contact us for more information.

Cat.No. Product Name Source Tag
Spike-678V Recombinant COVID-19 Omicron RBD(G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H) protein, His-tagged HEK293 His
Spike-679V Recombinant COVID-19 Omicron RBD(G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H) protein, His-Avi-tagged, Biotinylated HEK293 His-Avi
Spike-680V Recombinant COVID-19 Omicron S-ECD protein, His-tagged HEK293 His
Spike-681V Recombinant COVID-19 Omicron S-ECD protein, His-tagged Insect cell His
Spike-682V Recombinant COVID-19 Omicron S-ECD protein, His-Avi-tagged, Biotinylated HEK293 His-Avi
Spike-685V Recombinant COVID-19 Omicron S1(A67V, Δ69-70, T95I, G142D/Δ143-145, Δ211/L212I, ins214EPE, G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H, T547K, D614G, H655Y, N679K, P681H) protein, His-tagged HEK293 His
N-686V Recombinant COVID-19 Omicron N(P13L, E31del, R32del, S33del, R203K, G204R) protein, His-tagged E.coli His
Spike-687V Recombinant COVID-19 Omicron RBD(G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493K, G496S, Q498R, N501Y, Y505H) protein, His-tagged HEK293 His
Spike-688V Recombinant COVID-19 Omicron RBD(G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493K, G496S, Q498R, N501Y, Y505H) protein, His-Avi-tagged, Biotinylated HEK293 His-Avi
N-689V Recombinant COVID-19 Omicron N(P13L, E31del, R32del, S33del, R203K, G204R) protein, His-tagged HEK293 His
Cat.No. Product Name Source Tag
N-407S Recombinant SARS-CoV-2 Nucleocapsid (D63G, R203M, D377Y) Protein, His-tagged E.coli His
S-403S Recombinant SARS-CoV-2 Spike RBD (L452R, T478K) Protein, Fc-tagged HEK293 Fc
S-404S Recombinant SARS-CoV-2 Spike RBD (L452R, T478K) Protein, His/AVI-tagged, Biotinylated HEK293 His/AVI
S-411S Recombinant SARS-CoV-2 Spike S1 ((157-158) deletion, T19R, G142D, E156G, L452R, T478K, D614G, P681R) Protein, His/AVI-tagged, Biotinylated HEK293 His/AVI
S-415S Recombinant SARS-CoV-2 Spike RBD (L452R,T478K) Protein, His-tagged HEK293 His
S-416S Recombinant SARS-CoV-2 Spike RBD (T478K) Protein, His-tagged HEK293 His
S-418S Recombinant SARS-CoV-2 Spike S1+S2 ECD (T19R, G142D, E156G, HR157-158 deletion, L452R, T478K, D614G, P681R, D950N) Protein, His-tagged Insect Cell His
S-420S Recombinant SARS-CoV-2 Spike S1 (T19R, G142D, E156G, 157-158 deletion, L452R, T478K, D614G, P681R) Protein, His-tagged HEK293 His
S-421S Recombinant SARS-CoV-2 Spike S1 (T19R, G142D, L452R, E484Q, D614G, P681R) Protein, His-tagged HEK293 His
S-422S Recombinant SARS-CoV-2 Spike S1 (T19R, G142D, L452R, E484Q, D614G, P681R) Protein, His/AVI-tagged, Biotinylated HEK293 His/AVI
Cat.No. Product Name Source Tag
N-426S Recombinant SARS-CoV-2 (2019-nCoV) Nucleocapsid(R203K, G204R) Protein, His-tagged E.coli His
N-427S Recombinant SARS-CoV-2 (2019-nCoV) Nucleocapsid (E378Q) Protein, His-tagged E.coli His
N-428S Recombinant SARS-CoV-2 (2019-nCoV) Nucleocapsid(I292T) Protein, His-tagged E.coli His
N-429S Recombinant SARS-CoV-2 (2019-nCoV) Nucleocapsid(D3L, R203K, G204R, S235F) Protein, His-tagged E.coli His
N-430S Recombinant SARS-CoV-2 (2019-nCoV) Nucleocapsid(D3L, S235F) Protein, His-tagged E.coli His
N-441S Recombinant SARS-CoV-2 (2019-nCoV) Nucleocapsid(S194L) Protein, His-tagged E.coli His
S-431S Recombinant SARS-CoV-2 (2019-nCoV) Spike S1+S2 ECD (HV69-70 deletion, Y144 deletion, N501Y, A570D, D614G, P681H, T716I, S982A, D1118H) Protein, His-tagged Insect Cell His
S-432S Recombinant SARS-CoV-2 (2019-nCoV) Spike S1(HV69-70 deletion, Y144 deletion, N501Y, A570D, D614G, P681H) Protein, His-tagged HEK293 His
S-433S Recombinant SARS-CoV-2 Spike S1 ((HV69-70, Y145)deletion, N501Y, A570D, D614G, P681H) Protein, His/AVI-tagged, Biotinylated HEK293 His/AVI
S-434S Recombinant SARS-CoV-2 (2019-nCoV) Spike S1(HV69-70 deletion, Y144 deletion, N501Y, A570D, D614G, P681H) Protein, His-tagged, Biotinylated HEK293 His
S-435S Recombinant SARS-CoV-2 (2019-nCoV) Spike S1(HV69-70 deletion, N501Y, D614G) Protein, His-tagged HEK293 His
S-436S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(S494P) Protein, His-tagged HEK293 His
S-437S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(N501Y) Protein, His-tagged HEK293 His
S-438S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(N501Y) Protein, His-tagged, Biotinylated HEK293 His
S-439S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD (N501Y) Protein, rFc-tagged HEK293 rFc
S-440S Recombinant SARS-CoV-2 Spike RBD (N501Y) Protein, His/AVI-tagged, Biotinylated HEK293 His/AVI
Cat.No. Product Name Source Tag
N-444S Recombinant SARS-CoV-2 (2019-nCoV) Nucleocapsid (T205I) Protein, His-tagged E.coli His
S-443S Recombinant SARS-CoV-2 Spike RBD (K417N, E484K, N501Y) Protein, Fc-tagged HEK293 Fc
S-445S Recombinant SARS-CoV-2 Spike S1+S2 ECD (D80A, LAL242-244 deletion, R246I, K417N, E484K, N501Y, D614G, A701V) Protein, His-tagged Insect Cell His
S-446S Recombinant SARS-CoV-2 (2019-nCoV) Spike S1+S2 ECD (L18F, D80A, D215G, LAL242-244 deletion, R246I, K417N, E484K, N501Y, D614G, A701V) Protein, His-tagged Insect Cell His
S-447S Recombinant SARS-CoV-2 (2019-nCoV) Spike S1+S2 (L18F, D80A, D215G, LAL242-244 deletion, R246I, K417N, E484K, N501Y, D614G, A701V) Protein, His-tagged, Biotinylated Insect Cell His
S-448S Recombinant SARS-CoV-2 (2019-nCoV) Spike S1+S2 ECD (D80A, K417N, E484K, N501Y, D614G, A701V) Protein, His-tagged Insect Cell His
S-449S Recombinant SARS-CoV-2 (2019-nCoV) Spike S1(K417N, E484K, N501Y, D614G) Protein, His-tagged HEK293 His
S-450S Recombinant SARS-CoV-2 Spike S1 (K417N, E484K, N501Y, D614G) Protein, His-tagged HEK293 His
S-451S Recombinant SARS-CoV-2 (2019-nCoV) Spike S1 NTD (L18F, D80A, D215G, LAL242-244 deletion, R246I) Protein, His-tagged HEK293 His
S-452S Recombinant SARS-CoV-2 (2019-nCoV) Spike S1 (L18F, D80A, D215G, LAL242-244 deletion, R246I, K417N, E484K, N501Y, D614G) Protein, His-tagged HEK293 His
S-453S Recombinant SARS-CoV-2 Spike S1 ((LAL242-244)deletion, L18F, D80A, D215G, R246I, K417N, E484K, N501Y, D614G) Protein, His/AVI-tagged, Biotinylated HEK293 His/AVI
S-454S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(K417N) Protein, His-tagged HEK293 His
S-455S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(K417N) Protein, His-tagged, Biotinylated HEK293 His
S-456S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(E484K) Protein, His-tagged HEK293 His
S-457S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(E484K) Protein, His-tagged, Biotinylated HEK293 His
S-458S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(K417N, E484K, N501Y) Protein, His-tagged HEK293 His
S-459S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(K417N, E484K, N501Y) Protein, His-tagged, Biotinylated HEK293 His
S-460S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD (E484K) Protein, rFc-tagged HEK293 rFc
S-461S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD (K417N, E484K, N501Y) Protein, rFc-tagged HEK293 rFc
S-462S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD (K417N) Protein, rFc-tagged HEK293 rFc
S-463S Recombinant SARS-CoV-2 Spike RBD (K417T, E484K, N501Y) Protein, Fc-tagged HEK293 Fc
Cat.No. Product Name Source Tag
N-464S Recombinant SARS-CoV-2 (2019-nCoV) Nucleocapsid (P80R) Protein, His-tagged E.coli His
S-465S Recombinant SARS-CoV-2 (2019-nCoV) Spike S1+S2 ECD (L18F, T20N, P26S, D138Y, R190S, K417T, E484K, N501Y, D614G, H655Y, T1027I, V1176F) Protein, His-tagged Insect Cell His
S-466S Recombinant SARS-CoV-2 (2019-nCoV) Spike S1+S2 ECD (L18F, T20N, P26S, D138Y, R190S, K417T, E484K, N501Y, D614G, H655Y, T1027I) Protein, His-tagged Insect Cell His
S-467S Recombinant SARS-CoV-2 (2019-nCoV) Spike S1 (L18F, T20N, P26S, D138Y, R190S, K417T, E484K, N501Y, D614G, H655Y) Protein, His-tagged HEK293 His
S-468S Recombinant SARS-CoV-2 (2019-nCoV) Spike S1(T20N, D614G) Protein, His-tagged HEK293 His
S-469S Recombinant SARS-CoV-2 Spike S1 (L18F, T20N, P26S, D138Y, R190S, K417T, E484K, N501Y, D614G, H655Y) Protein, His/AVI-tagged, Biotinylated HEK293 His/AVI
S-470S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD (K417T, E484K, N501Y) Protein, His-tagged HEK293 His
S-471S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD (K417T, E484K, N501Y) Protein, rFc-tagged HEK293 rFc
S-472S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD (K417T) Protein, rFc-tagged HEK293 rFc
S-473S Recombinant SARS-CoV-2 Spike RBD (E484K, K417T, N501Y) Protein, His/AVI-tagged, Biotinylated HEK293 His/AVI
Cat.No. Product Name Source Tag
N-588S Recombinant SARS-CoV-2 Nucleocapsid (S202N) Protein, His-tagged E.coli His
Cat.No. Product Name Source Tag
N-479S Recombinant SARS-CoV-2 (2019-nCoV) Nucleocapsid(P13L) Protein, His-tagged E.coli His
Cat.No. Product Name Source Tag
S-425S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD (N501Y) Protein, Fc-tagged HEK293 Fc
Cat.No. Product Name Source Tag
N-587S Recombinant SARS-CoV-2 Nucleocapsid (P67S, P199L) Protein, His-tagged E.coli His
Cat.No. Product Name Source Tag
N-408S Recombinant SARS-CoV-2 Nucleocapsid (P67S, R203M, D377Y) Protein, His-tagged E.coli His
Cat.No. Product Name Source Tag
N-584S Recombinant SARS-CoV-2 Nucleocapsid (P199L, M234I) Protein, His-tagged E.coli His
Cat.No. Product Name Source Tag
N-424S Recombinant SARS-CoV-2 (2019-nCoV) Nucleocapsid (T205I) Protein, His-tagged E.coli His
N-442S Recombinant SARS-CoV-2 (2019-nCoV) Nucleocapsid(P13L) Protein, His-tagged E.coli His
N-477S Recombinant SARS-CoV-2 (2019-nCoV) Nucleocapsid(R203K, G204R) Protein, His-tagged E.coli His
N-478S Recombinant SARS-CoV-2 (2019-nCoV) Nucleocapsid (P80R) Protein, His-tagged E.coli His
N-480S Recombinant SARS-CoV-2 (2019-nCoV) Nucleocapsid(S194L) Protein, His-tagged E.coli His
N-481S Recombinant SARS-CoV-2 (2019-nCoV) Nucleocapsid(I292T) Protein, His-tagged E.coli His
N-482S Recombinant SARS-CoV-2 (2019-nCoV) Nucleocapsid (T205I) Protein, His-tagged E.coli His
N-580S Recombinant SARS-CoV-2 Nucleocapsid (P199L) Protein, His-tagged E.coli His
N-581S Recombinant SARS-CoV-2 Nucleocapsid (A220V) Protein, His-tagged E.coli His
N-582S Recombinant SARS-CoV-2 Nucleocapsid (P67S) Protein, His-tagged E.coli His
N-583S Recombinant SARS-CoV-2 Nucleocapsid (M234L) Protein, His-tagged E.coli His
S-401S Recombinant SARS-CoV-2 Spike RBD (L452R, E484Q) Protein, Fc-tagged HEK293 Fc
S-402S Recombinant SARS-CoV-2 Spike RBD (L452R, E484Q) Protein, His/AVI-tagged, Biotinylated HEK293 His/AVI
S-409S Recombinant SARS-CoV-2 Spike S1+S2 ECD (E154K, L452R, E484Q, D614G, P681R, E1072K, K1073R) Protein, His-tagged Insect Cell His
S-410S Recombinant SARS-CoV-2 Spike S1 (E154K, L452R, E484Q, D614G, P681R) Protein, His-tagged HEK293 His
S-412S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(L452R) Protein, His-tagged HEK293 His
S-413S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(E484Q) Protein, His-tagged HEK293 His
S-414S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD (L452R, E484Q) Protein, His-tagged HEK293 His
S-484S Recombinant SARS-CoV-2 (2019-nCoV) Spike S1+S2 ECD (D614G) Protein, His-tagged Insect Cell His
S-485S Recombinant SARS-CoV-2 (2019-nCoV) Spike S1+S2 ECD (HV69-70 deletion, D614G, D796H) Protein, His-tagged Insect Cell His
S-486S Recombinant SARS-CoV-2 (2019-nCoV) Spike S2 (E780Q) Protein, Fc-tagged HEK293 Fc
S-487S Recombinant SARS-CoV-2 (2019-nCoV) Spike S1(D614G), Fc-tagged HEK293 Fc
S-488S Recombinant SARS-CoV-2 (2019-nCoV) Spike S1(N234Q) Protein, His-tagged HEK293 His
S-491S Recombinant SARS-CoV-2 (2019-nCoV) Spike S1(D614G) Protein, His-tagged, HPLC-verified HEK293 His
S-492S Recombinant SARS-CoV-2 (2019-nCoV) Spike S1(A222V, D614G) Protein, His-tagged HEK293 His
S-493S Recombinant SARS-CoV-2 (2019-nCoV) Spike S1(L18F, D614G) Protein, His-tagged HEK293 His
S-494S Recombinant SARS-CoV-2 (2019-nCoV) Spike S1(HV69-70 deletion, N439K, D614G) Protein, His-tagged HEK293 His
S-495S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD (V367F) Protein, mFcs-tagged HEK293 mFc
S-496S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD (V367F) Protein, His-tagged HEK293 His
S-497S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(R408I) Protein, His-tagged HEK293 His
S-498S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(V341I) Protein, His-tagged HEK293 His
S-499S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(Y508H) Protein, His-tagged HEK293 His
S-500S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(N439K) Protein, His-tagged HEK293 His
S-501S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(V503F) Protein, His-tagged HEK293 His
S-502S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(A522V) Protein, His-tagged HEK293 His
S-503S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(A372S) Protein, His-tagged HEK293 His
S-504S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD (N354D) Protein, His-tagged HEK293 His
S-505S Recombinant SARS-CoV-2 Spike RBD (N354D) Protein, His-tagged, Biotinylated HEK293 His
S-506S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(A520S) Protein, His-tagged HEK293 His
S-507S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(A522S) Protein, His-tagged HEK293 His
S-508S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(D405V, Q414A) Protein, His-tagged HEK293 His
S-509S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(Q414E) Protein, His-tagged HEK293 His
S-510S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(P384L) Protein, His-tagged HEK293 His
S-511S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(A348S) Protein, His-tagged HEK293 His
S-512S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(F338L) Protein, His-tagged HEK293 His
S-513S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(F377L) Protein, His-tagged HEK293 His
S-514S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(P521S) Protein, His-tagged HEK293 His
S-515S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(T478I) Protein, His-tagged HEK293 His
S-516S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(V483I) Protein, His-tagged HEK293 His
S-517S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(S359N) Protein, His-tagged HEK293 His
S-518S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(K378R) Protein, His-tagged HEK293 His
S-519S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(Q409E) Protein, His-tagged HEK293 His
S-520S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(I472V) Protein, His-tagged HEK293 His
S-521S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(A372T) Protein, His-tagged HEK293 His
S-522S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(A344S) Protein, His-tagged HEK293 His
S-523S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(A520V) Protein, His-tagged HEK293 His
S-524S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD (A435S) Protein, His-tagged HEK293 His
S-525S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(E406Q) Protein, His-tagged HEK293 His
S-526S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(F490S) Protein, His-tagged HEK293 His
S-527S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(K378N) Protein, His-tagged HEK293 His
S-528S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(N370S) Protein, His-tagged HEK293 His
S-529S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(Q414R) Protein, His-tagged HEK293 His
S-530S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(S477I) Protein, His-tagged HEK293 His
S-531S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(S477N) Protein, His-tagged HEK293 His
S-532S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(T385A) Protein, His-tagged HEK293 His
S-533S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(T393P) Protein, His-tagged HEK293 His
S-534S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(V395I) Protein, His-tagged HEK293 His
S-535S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD (V483A) Protein, His-tagged HEK293 His
S-536S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(A475V) Protein, His-tagged HEK293 His
S-537S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(G446V) Protein, His-tagged HEK293 His
S-538S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(G485S) Protein, His-tagged HEK293 His
S-539S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(G482S) Protein, His-tagged HEK293 His
S-540S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(K444R) Protein, His-tagged HEK293 His
S-541S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(N440K) Protein, His-tagged HEK293 His
S-542S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(E471Q) Protein, His-tagged HEK293 His
S-543S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(P479S) Protein, His-tagged HEK293 His
S-544S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(A352S) Protein, His-tagged HEK293 His
S-545S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD (F342L) Protein, His-tagged HEK293 His
S-546S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(P337S) Protein, His-tagged HEK293 His
S-547S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(P521R) Protein, His-tagged HEK293 His
S-548S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(S477R) Protein, His-tagged HEK293 His
S-549S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(L455F) Protein, His-tagged HEK293 His
S-550S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(K458Q) Protein, His-tagged HEK293 His
S-551S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD (K458R) Protein, His-tagged HEK293 His
S-552S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(N481D) Protein, His-tagged HEK293 His
S-553S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(F456L) Protein, His-tagged HEK293 His
S-554S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(Y505C) Protein, His-tagged HEK293 His
S-555S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(F456E) Protein, His-tagged HEK293 His
S-556S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(F486S) Protein, His-tagged HEK293 His
S-557S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(N487R) Protein, His-tagged HEK293 His
S-558S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(G446S) Protein, His-tagged HEK293 His
S-559S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(P499R) Protein, His-tagged HEK293 His
S-560S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(V445F) Protein, His-tagged HEK293 His
S-561S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(G476S) Protein, His-tagged HEK293 His
S-562S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(F490L) Protein, His-tagged HEK293 His
S-563S Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD (W436R) Protein, His-tagged HEK293 His
S-564S Recombinant SARS-CoV-2 Spike RBD (N440D) Protein, His-tagged HEK293 His
S-565S Recombinant SARS-CoV-2 Spike RBD (F456Y) Protein, His-tagged HEK293 His
S-566S Recombinant SARS-CoV-2 Spike RBD (E471A) Protein, His-tagged HEK293 His
S-567S Recombinant SARS-CoV-2 Spike RBD (E471D) Protein, His-tagged HEK293 His
S-568S Recombinant SARS-CoV-2 Spike RBD (Y473F) Protein, His-tagged HEK293 His
S-569S Recombinant SARS-CoV-2 Spike RBD (A475T) Protein, His-tagged HEK293 His
S-570S Recombinant SARS-CoV-2 Spike RBD (G476A) Protein, His-tagged HEK293 His
S-571S Recombinant SARS-CoV-2 Spike RBD (S477G) Protein, His-tagged HEK293 His
S-572S Recombinant SARS-CoV-2 Spike RBD (P479L) Protein, His-tagged HEK293 His
S-573S Recombinant SARS-CoV-2 Spike RBD (P479H) Protein, His-tagged HEK293 His
S-574S Recombinant SARS-CoV-2 Spike RBD (N481K) Protein, His-tagged HEK293 His
S-575S Recombinant SARS-CoV-2 Spike RBD (E484A) Protein, His-tagged HEK293 His
S-576S Recombinant SARS-CoV-2 Spike RBD (E484D) Protein, His-tagged HEK293 His
S-577S Recombinant SARS-CoV-2 Spike RBD (N487D) Protein, His-tagged HEK293 His
S-578S Recombinant SARS-CoV-2 Spike RBD (Y449H) Protein, His-tagged HEK293 His
S-579S Recombinant SARS-CoV-2 Spike RBD (G502V) Protein, His-tagged HEK293 His

According to the new statistics from the WHO, there are 147 vaccine projects in various stages of development worldwide for the COVID19, of which 18 have entered clinical trials.

Coronavirus uses its spike glycoprotein (S), a main target for neutralization antibody, to bind to its receptor, and mediate membrane fusion and virus entry. Its receptor binding domain (RBD) has a high affinity with the ACE2 receptor protein on the surface of human cells. The S protein is an ideal entry point for vaccine design. The neutralizing antibody binds to the viral S protein RBD to competitively block the virus binding to the ACE2 protein and infect cells, achieving the effect of immune prevention and even treatment.

We can now offer mutant spike RBD proteins, which are thermally stable and can produce antibodies with neutralizing activity. We will continue to work together with the worldwide scientists to find the path forward for today’s challenges, and to support tomorrow’s breakthroughs.

Cat# Product Name Identity Source
Spike-011V Recombinant 2019-nCoV Spike RBD(L452R, E484Q) Protein, His-tagged S1(RBD)(L452R, E484Q)-His HEK293
Spike-012V Recombinant 2019-nCoV Spike RBD(D377Y) Protein, His-tagged S1(RBD)(D377Y)-His E. coli
Spike-014V Recombinant 2019-nCoV S1(HV69-70del, Y144del, N501Y, A570D, D614G, P681H) Protein, His-tagged, Biotinylated S1(HV69-70del, Y144del, N501Y, A570D, D614G, P681H)-His HEK293
Spike-016V Recombinant 2019-nCoV Spike RBD(N501Y) Protein, His-tagged at the C-terminus, Biotinylated S1(RBD)(N501Y)-His HEK293
Spike-017V Recombinant 2019-nCoV Spike RBD(E484K) Protein, His-tagged, Biotinylated S1(RBD)(E484K)-His HEK293
Spike-018V Recombinant 2019-nCoV Spike S1 ( E154K, L452R, E484Q, D614G, P681R) Protein, His-tagged S1 ( E154K, L452R, E484Q, D614G, P681R)-His HEK293
Spike-019V Recombinant 2019-nCoV Spike S1(W152C, L452R, D614G) Protein, His-tagged S1(W152C, L452R, D614G)-His HEK293
N-021V Recombinant 2019-nCoV N(E378Q) Protein, His-tagged N(E378Q)-His E. coli
Spike-023V Recombinant 2019-nCoV Spike S1+S2 ECD(D80A, LAL242-244 deletion, R246I, K417N, E484K, N501Y, D614G, A701V) Protein, His-tagged S1+S2 ECD(D80A, LAL242-244 deletion, R246I, K417N, E484K, N501Y, D614G, A701V)-His Insect Cells
Spike-024V Recombinant 2019-nCoV Spike S1+S2 ECD(L18F, D80A, D215G, LAL242-244 deletion, R246I, K417N, E484K, N501Y, D614G, A701VV) Protein, His-tagged S1+S2 ECD(L18F, D80A, D215G, LAL242-244 deletion, R246I, K417N, E484K, N501Y, D614G, A701VV)-His Insect Cells
Spike-025V Recombinant 2019-nCoV Spike S1+S2 ECD(L18F, D80A, D215G, LAL242-244 deletion, R246I, K417N, E484K, N501Y, D614G, A701V) Protein, His-tagged, Biotinylated S1+S2 ECD(L18F, D80A, D215G, LAL242-244 deletion, R246I, K417N, E484K, N501Y, D614G, A701V)-His Insect Cells
Spike-026V Recombinant 2019-nCoV Spike S1+S2 ECD(D80A, K417N, E484K, N501Y, D614G, A701V) Protein, His-tagged, Biotinylated S1+S2 ECD(D80A, K417N, E484K, N501Y, D614G, A701V)-His Insect Cells
Spike-027V Recombinant 2019-nCoV Spike S1 NTD(L18F, D80A, D215G, LAL242-244 deletion, R246I) Protein, His-tagged S1 NTD(L18F, D80A, D215G, LAL242-244 deletion, R246I)-His HEK293
Spike-028V Recombinant 2019-nCoV Spike S1(L18F, D80A, D215G, LAL242-244 deletion, R246I, K417N, E484K, N501Y, D614G) Protein, His-tagged, Biotinylated S1(L18F, D80A, D215G, LAL242-244 deletion, R246I, K417N, E484K, N501Y, D614G)-His HEK293
Spike-029V Recombinant 2019-nCoV Spike RBD(K417N) Protein, His-tagged, Biotinylated S1(RBD)(K417N)-His HEK293
Spike-030V Recombinant 2019-nCoV Spike RBD(K417N, E484K, N501Y) Protein, His-tagged, Biotinylated S1(RBD)(K417N, E484K, N501Y)-His HEK293
Spike-031V Recombinant 2019-nCoV Spike RBD(E484K) Protein, rFc-tagged S1(RBD)(E484K)-His HEK293
Spike-032V Recombinant 2019-nCoV Spike RBD(K417N, E484K, N501Y) Protein, rFc-tagged S1(RBD)(K417N, E484K, N501Y)-His HEK293
Spike-033V Recombinant 2019-nCoV Spike RBD(K417N) Protein, rFc-tagged S1(RBD)(K417N)-His HEK293
Spike-035V Recombinant 2019-nCoV Spike S1+S2 ECD(L18F, T20N, P26S, D138Y, R190S, K417T, E484K, N501Y, D614G, H655Y, T1027I, V1176F) Protein, His-tagged S1+S2 ECD(L18F, T20N, P26S, D138Y, R190S, K417T, E484K, N501Y, D614G, H655Y, T1027I, V1176F)-His Insect Cells
Spike-036V Recombinant 2019-nCoV Spike S1+S2 ECD(L18F, T20N, P26S, D138Y, R190S, K417T, E484K, N501Y, D614G, H655Y, T1027I) Protein, His-tagged S1+S2 ECD(L18F, T20N, P26S, D138Y, R190S, K417T, E484K, N501Y, D614G, H655Y, T1027I)-His Insect Cells
Spike-037V Recombinant 2019-nCoV S1(L18F, T20N, P26S, D138Y, R190S, K417T, E484K, N501Y, D614G, H655Y) Protein, His-tagged S1(L18F, T20N, P26S, D138Y, R190S, K417T, E484K, N501Y, D614G, H655Y)-His HEK293
Spike-038V Recombinant 2019-nCoV Spike RBD(K417T, E484K, N501Y) Protein, rFc-tagged S1(RBD)(K417T, E484K, N501Y)-His HEK293
Spike-039V Recombinant 2019-nCoV Spike RBD(K417T) Protein, rFc-tagged S1(RBD)(K417T)-His HEK293
Spike-040V Recombinant 2019-nCoV Spike RBD(Y453F) Protein, rFc-tagged S1(RBD)(Y453F)-His HEK293
N-041V Recombinant 2019-nCoV N(P80R) Protein, His-tagged N(P80R)-His E. coli
N-042V Recombinant 2019-nCoV N(T205I) Protein, His-tagged N(T205I)-His E. coli
Spike-043V Recombinant 2019-nCoV Spike S1+S2 ECD(D614G) Protein, His-tagged S1+S2 ECD(D614G)-His Insect Cells
Spike-044V Recombinant 2019-nCoV Spike S1+S2 ECD(HV69-70 deletion, D614G, D796H) Protein, His-tagged S1+S2 ECD(HV69-70 deletion, D614G, D796H)-His Insect Cells
Spike-055V Recombinant 2019-nCoV Spike S2 ECD(E780Q) Protein, Fc-tagged S1S2 ECD(E780Q)-His HEK293
Spike-056V Recombinant 2019-nCoV Spike S1 ECD(D614G) Protein, Fc-tagged S1 ECD(D614G)-His HEK293
Spike-057V Recombinant 2019-nCoV Spike S1(Q677H) Protein, His-tagged S1(Q677H)-His HEK293
Spike-082V Recombinant 2019-nCoV Spike RBD (L452R, E484Q) Protein, His-Avi-tagged, Biotinylated S1(L452R, E484Q)-His HEK293
Spike-083V Recombinant 2019-nCoV Spike RBD (L452R, E484Q) Protein, His-tagged S1(L452R, E484Q)-His HEK293
Spike-084V Recombinant 2019-nCoV Spike S1(K417N, E484K, N501Y, D614G) Protein, His-tagged S1(K417N, E484K, N501Y, D614G)-His HEK293
Spike-085V Recombinant 2019-nCoV Spike S1(HV69-70 deletion, Y144 deletion, N501Y, A570D, D614G, P681H) Protein, His-tagged S1(HV69-70 deletion, Y144 deletion, N501Y, A570D, D614G, P681H)-His HEK293
Spike-086V Recombinant 2019-nCoV Spike RBD (N501Y) Protein, Fc-tagged S1 RBD(N501Y)-Fc HEK293
Spike-048V Recombinant 2019-nCoV S1+S2 ECD(HV69-70del, Y144del, N501Y, A570D, D614G, P681H, T716I, S982A, D1118H) Protein, His-tagged S1+S2 ECD(HV69-70del, Y144del, N501Y, A570D, D614G, P681H, T716I, S982A, D1118H)-His HEK293
Spike-02D Recombinant 2019-nCoV S1+S2 ECD(Y453F, 69-70del, I692V) Protein, His-tagged S1+S2 ECD(Y453F, 69-70del, I692V)-His Insect cells
Spike-045V Recombinant 2019-nCoV Spike S1(HV69-70del, N501Y, D614G) Protein, His-tagged S1(HV69-70del, N501Y, D614G)-His HEK293
Spike-046V Recombinant 2019-nCoV Spike S1(N501Y) Protein, His-tagged S1(N501Y)-His HEK293
Spike-047V Recombinant 2019-nCoV Spike RBD(K417N, E484K, N501Y) Protein, His-tagged S1 RBD(K417N, E484K, N501Y)-His HEK293
Spike-03S Recombinant 2019-nCoV S1+S2 ECD(L18F, D80A, D215G, 242-244 deletion, R246I, K417N, E484K, N501Y, A701V) Protein, His-tagged S1+S2 ECD(L18F, D80A, D215G, 242-244 deletion, R246I, K417N, E484K, N501Y, A701V)-His Insect cells
Spike-01U Recombinant 2019-nCoV S1+S2 ECD(HV69-70del, Y144del, N501Y, A570D, D614G, P681H, T716I, S982A, D1118H) Protein, His-tagged S1+S2 ECD(HV69-70del, Y144del, N501Y, A570D, D614G, P681H, T716I, S982A, D1118H)-His Insect cells
Spike-145V Recombinant 2019-nCoV Spike protein RBD(N501Y), His-tagged S1(RBD)(N501Y)-His HEK293
Spike-213V Recombinant COVID-19 S protein RBD(N354D), His-tagged S1(RBD)(N354D)-His HEK293
Spike-214V Recombinant COVID-19 S protein RBD (N354D, D364Y), His-tagged S1(RBD)(N354D, D364Y)-His HEK293
Spike-215V Recombinant COVID-19 S protein RBD (W436R), His-tagged S1(RBD)(W436R)-His HEK293
Spike-216V Recombinant COVID-19 S protein RBD (R408I), His-tagged S1(RBD)(R408I)-His HEK293
Spike-219V Recombinant COVID-19 Spike S1 (D614G) protein, His-tagged S1(D614G)-His HEK293
Spike-220V Recombinant COVID-19 Spike RBD (K458R) protein, His-tagged S1(RBD)(K458R)-His HEK293
Spike-221V Recombinant COVID-19 Spike RBD (F342L) protein, His-tagged S1(RBD)(F342L)-His HEK293
Spike-222V Recombinant COVID-19 Spike RBD (V483A) protein, His-tagged S1(RBD)(V483A)-His HEK293
Spike-223V Recombinant COVID-19 Spike RBD (A435S) protein, His-tagged S1(RBD)(A435S)-His HEK293
Spike-224V Recombinant COVID-19 Spike RBD (G476S) protein, His-tagged S1(RBD)(G476S)-His HEK293
Spike-300V Recombinant COVID-19 Spike RBD (V367F) protein, mFc-tagged S1(RBD)(V367F)-His HEK293
Spike-301V Recombinant COVID-19 Spike RBD (V341I) protein, His-tagged S1(RBD)(V341I)-His HEK293
Spike-302V Recombinant COVID-19 Spike RBD (Y508H) protein, His-tagged S1(RBD)(Y508H)-His HEK293
Spike-303V Recombinant COVID-19 Spike RBD (N439K) protein, His-tagged S1(RBD)(N439K)-His HEK293
Spike-304V Recombinant COVID-19 Spike RBD (V503F) protein, His-tagged S1(RBD)(V503F)-His HEK293
Spike-305V Recombinant COVID-19 Spike RBD (A522V) protein, His-tagged S1(RBD)(A522V)-His HEK293
Spike-306V Recombinant COVID-19 Spike RBD (S494P) protein, His-tagged S1(RBD)(S494P)-His HEK293
Spike-307V Recombinant COVID-19 Spike RBD (A372S) protein, His-tagged S1(RBD)(A372S)-His HEK293
Spike-308V Recombinant COVID-19 Spike RBD (A520S) protein, His-tagged S1(RBD)(A520S)-His HEK293
Spike-309V Recombinant COVID-19 Spike RBD (A522S) protein, His-tagged S1(RBD)(A522S)-His HEK293
Spike-310V Recombinant COVID-19 Spike RBD (D405V, Q414A) protein, His-tagged S1(RBD)(D405V, Q414A)-His HEK293
Spike-311V Recombinant COVID-19 Spike RBD (Q414E) protein, His-tagged S1(RBD)(Q414E)-His HEK293
Spike-312V Recombinant COVID-19 Spike RBD (P384L) protein, His-tagged S1(RBD)(P384L)-His HEK293
Spike-313V Recombinant COVID-19 Spike RBD (A348S) protein, His-tagged S1(RBD)(A348S)-His HEK293
Spike-314V Recombinant COVID-19 Spike RBD (F338L) protein, His-tagged S1(RBD)(F338L)-His HEK293
Spike-315V Recombinant COVID-19 Spike RBD (F377L) protein, His-tagged S1(RBD)(F377L)-His HEK293
Spike-316V Recombinant COVID-19 Spike RBD (L452R) protein, His-tagged S1(RBD)(L452R)-His HEK293
Spike-317V Recombinant COVID-19 Spike RBD (P521S) protein, His-tagged S1(RBD)(P521S)-His HEK293
Spike-318V Recombinant COVID-19 Spike RBD (T478I) protein, His-tagged S1(RBD)(T478I)-His HEK293
Spike-319V Recombinant COVID-19 Spike RBD (V483I) protein, His-tagged S1(RBD)(V483I)-His HEK293
Spike-320V Recombinant COVID-19 Spike RBD (S359N) protein, His-tagged S1(RBD)(S359N)-His HEK293
Spike-321V Recombinant COVID-19 Spike RBD (K378R) protein, His-tagged S1(RBD)(K378R)-His HEK293
Spike-322V Recombinant COVID-19 Spike RBD (Q409E) protein, His-tagged S1(RBD)(Q409E)-His HEK293
Spike-323V Recombinant COVID-19 Spike RBD (I472V) protein, His-tagged S1(RBD)(I472V)-His HEK293
Spike-324V Recombinant COVID-19 Spike RBD (A372T) protein, His-tagged S1(RBD)(A372T)-His HEK293
Spike-325V Recombinant COVID-19 Spike RBD (A344S) protein, His-tagged S1(RBD)(A344S)-His HEK293
Spike-326V Recombinant COVID-19 Spike RBD (A520V) protein, His-tagged S1(RBD)(A520V)-His HEK293
Spike-327V Recombinant COVID-19 Spike RBD (E406Q) protein, His-tagged S1(RBD)(E406Q)-His HEK293
Spike-328V Recombinant COVID-19 Spike RBD (F490S) protein, His-tagged S1(RBD)(F490S)-His HEK293
Spike-329V Recombinant COVID-19 Spike RBD (K378N) protein, His-tagged S1(RBD)(K378N)-His HEK293
Spike-330V Recombinant COVID-19 Spike RBD (N370S) protein, His-tagged S1(RBD)(N370S)-His HEK293
Spike-331V Recombinant COVID-19 Spike RBD (Q414R) protein, His-tagged S1(RBD)(Q414R)-His HEK293
Spike-332V Recombinant COVID-19 Spike RBD (S477I) protein, His-tagged S1(RBD)(S477I)-His HEK293
Spike-333V Recombinant COVID-19 Spike RBD (S477N) protein, His-tagged S1(RBD)(S477N)-His HEK293
Spike-334V Recombinant COVID-19 Spike RBD (T385A) protein, His-tagged S1(RBD)(T385A)-His HEK293
Spike-335V Recombinant COVID-19 Spike RBD (T393P) protein, His-tagged S1(RBD)(T393P)-His HEK293
Spike-336V Recombinant COVID-19 Spike RBD (V395I) protein, His-tagged S1(RBD)(V395I)-His HEK293
Spike-337V Recombinant COVID-19 Spike RBD (G485S) protein, His-tagged S1(RBD)(G485S)-His HEK293
Spike-338V Recombinant COVID-19 Spike RBD (G482S) protein, His-tagged S1(RBD)(G482S)-His HEK293
Spike-339V Recombinant COVID-19 Spike RBD (K444R) protein, His-tagged S1(RBD)(K444R)-His HEK293
Spike-340V Recombinant COVID-19 Spike RBD (N440K) protein, His-tagged S1(RBD)(N440K)-His HEK293
Spike-341V Recombinant COVID-19 Spike RBD (E471Q) protein, His-tagged S1(RBD)(E471Q)-His HEK293
Spike-342V Recombinant COVID-19 Spike RBD (P479S) protein, His-tagged S1(RBD)(P479S)-His HEK293
Spike-343V Recombinant COVID-19 Spike RBD (A352S) protein, His-tagged S1(RBD)(A352S)-His HEK293
Spike-344V Recombinant COVID-19 Spike RBD (K417N) protein, His-tagged S1(RBD)(K417N)-His HEK293
Spike-345V Recombinant COVID-19 Spike RBD (P337S) protein, His-tagged S1(RBD)(P337S)-His HEK293
Spike-346V Recombinant COVID-19 Spike RBD (P521R) protein, His-tagged S1(RBD)(P521R)-His HEK293
Spike-347V Recombinant COVID-19 Spike RBD (S477R) protein, His-tagged S1(RBD)(S477R)-His HEK293
N-348V Recombinant 2019-nCoV N(P13L) Protein, His-tagged N(P13L)-His E. coli
N-349V Recombinant 2019-nCoV N(S194L) Protein, His-tagged N(S194L)-His E. coli
N-350V Recombinant 2019-nCoV N(R203K, G204R) Protein, His-tagged N(R203K, G204R)-His E. coli
N-351V Recombinant 2019-nCoV N(I292T) Protein, His-tagged N(I292T)-His E. coli
N-352V Recombinant 2019-nCoV N(D3L, R203K, G204R, S235F) Protein, His-tagged N(D3L, R203K, G204R, S235F)-His E. coli
N-353V Recombinant 2019-nCoV N(D3L, S235F) Protein, His-tagged N(D3L, S235F)-His E. coli
Spike-354V Recombinant 2019-nCoV Spike RBD(V445F) Protein, His-tagged S1(RBD)(V445F)-His HEK293
Spike-355V Recombinant 2019-nCoV Spike RBD(G446S) Protein, His-tagged S1(RBD)(G446S)-His HEK293
Spike-356V Recombinant 2019-nCoV Spike RBD(G446V) Protein, His-tagged S1(RBD)(G446V)-His HEK293
Spike-357V Recombinant 2019-nCoV Spike RBD(Y453F) Protein, His-tagged S1(RBD)(Y453F)-His HEK293
Spike-358V Recombinant 2019-nCoV Spike RBD(L455F) Protein, His-tagged S1(RBD)(L455F)-His HEK293
Spike-359V Recombinant 2019-nCoV Spike RBD(F456E) Protein, His-tagged S1(RBD)(F456E)-His HEK293
Spike-360V Recombinant 2019-nCoV Spike RBD(F456L) Protein, His-tagged S1(RBD)(F456L)-His HEK293
Spike-361V Recombinant 2019-nCoV Spike RBD(K458Q) Protein, His-tagged S1(RBD)(K458Q)-His HEK293
Spike-362V Recombinant 2019-nCoV Spike RBD(N481D) Protein, His-tagged S1(RBD)(N481D)-His HEK293
Spike-363V Recombinant 2019-nCoV Spike RBD(E484K) Protein, His-tagged S1(RBD)(E484K)-His HEK293
Spike-364V Recombinant 2019-nCoV Spike RBD(E484Q) Protein, His-tagged S1(RBD)(E484Q)-His HEK293
Spike-365V Recombinant 2019-nCoV Spike RBD(F486S) Protein, His-tagged S1(RBD)(F486S)-His HEK293
Spike-366V Recombinant 2019-nCoV Spike RBD(N487R) Protein, His-tagged S1(RBD)(N487R)-His HEK293
Spike-367V Recombinant 2019-nCoV Spike RBD(F490L) Protein, His-tagged S1(RBD)(F490L)-His HEK293
Spike-368V Recombinant 2019-nCoV Spike RBD(P499R) Protein, His-tagged S1(RBD)(P499R)-His HEK293
Spike-369V Recombinant 2019-nCoV Spike RBD(Y505C) Protein, His-tagged S1(RBD)(Y505C)-His HEK293
Spike-370V Recombinant 2019-nCoV Spike S1(HV69-70 deletion, Y453F, D614G) Protein, His-tagged S1(HV69-70 deletion, Y453F, D614G)-His HEK293
Spike-371V Recombinant 2019-nCoV Spike S1(HV69-70 deletion, N439K, D614G) Protein, His-tagged S1(HV69-70 deletion, N439K, D614G)-His HEK293
Spike-372V Recombinant 2019-nCoV Spike S1(L18F, D614G) Protein, His-tagged S1(L18F, D614G)-His HEK293
Spike-373V Recombinant 2019-nCoV Spike S1(T20N, D614G) Protein, His-tagged S1(T20N, D614G)-His HEK293
Spike-374V Recombinant 2019-nCoV Spike S1(A222V, D614G) Protein, His-tagged S1(A222V, D614G)-His HEK293
Spike-375V Recombinant 2019-nCoV Spike S1(N234Q) Protein, His-tagged S1(N234Q)-His HEK293
Spike-376V Recombinant 2019-nCoV Spike S1 ECD (D614G) Protein, Fc-tagged S1 ECD (D614G)-His HEK293
Spike-377V Recombinant 2019-nCoV Spike S1+S2 ECD (R683A, R685A, F817P, A892P, A899P, A942P, K986P, V987P) Protein, His-tagged S1+S2 ECD (R683A, R685A, F817P, A892P, A899P, A942P, K986P, V987P)-His HEK293
Spike-378V Recombinant COVID-19 Spike RBD (L18F, T20N, P26S, D138Y, R190S, K417T, E484K, N501Y, D614G, H655Y, T1027I, V1176F) protein, His-tagged S1(RBD) (L18F, T20N, P26S, D138Y, R190S, K417T, E484K, N501Y, D614G, H655Y, T1027I, V1176F)-His HEK293
Spike-379V Recombinant COVID-19 Spike RBD (D614G) protein, His-Avi-tagged S1(RBD) (D614G)-His HEK293
Spike-380V Recombinant COVID-19 Spike RBD (L18F, D80A, D215G, R246I, K417N, E484K, N501Y, D614G, A701V) protein, His-tagged S1(RBD) (L18F, D80A, D215G, R246I, K417N, E484K, N501Y, D614G, A701V)-His HEK293
Spike-381V Recombinant COVID-19 S1 (HV69-70del) protein, His-tagged S1 (HV69-70del)-His HEK293
Spike-382V Recombinant COVID-19 S1 (Y144del) protein, His-tagged S1 (Y144del)-His HEK293
Spike-383V Recombinant COVID-19 S1 NTD(A222V) protein, His-tagged S1 NTD(A222V)-His HEK293
Spike-384V Recombinant COVID-19 S1 NTD(A262S) protein, His-tagged S1 NTD(A262S)-His HEK293
Spike-385V Recombinant COVID-19 S1 NTD(P272L) protein, His-tagged S1 NTD(P272L)-His HEK293
Spike-386V Recombinant COVID-19 S1 NTD(L18F, D80A, D215G, R246I) protein, His-tagged S1 NTD(L18F, D80A, D215G, R246I)-His HEK293
Spike-387V Recombinant COVID-19 Spike RBD (V367F) protein, His-tagged S1(RBD) (V367F)-His HEK293
Spike-388V Recombinant COVID-19 Spike RBD (A475V) protein, His-tagged S1(RBD) (A475V)-His HEK293
Spike-389V Recombinant COVID-19 Spike RBD (K417T, E484K, N501Y) protein, His-tagged S1(RBD) (K417T, E484K, N501Y)-His HEK293
Spike-390V Recombinant COVID-19 S1 (A570D) protein, His-tagged S1 (A570D)-His HEK293
Spike-391V Recombinant COVID-19 S1 (D614G) protein, His-Avi-tagged S1 (D614G)-His HEK293
Spike-392V Recombinant COVID-19 S1 (P681H) protein, His-tagged S1 (P681H)-His HEK293
Spike-393V Recombinant COVID-19 S1 (L18F, D80A, D215G, R246I, K417N, E484K, N501Y, D614G) protein, His-tagged S1 (L18F, D80A, D215G, R246I, K417N, E484K, N501Y, D614G)-His HEK293
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