Specially Designed Labeled Protein for Car-T Therapy
For years, the foundations of cancer treatment were surgery, chemotherapy, and radiation therapy. But over the past several years, immunotherapy has emerged as what many in the cancer community now call the "fifth pillar" of cancer treatment.
CAR T-cell therapy is a type of immunotherapy that changes a patient's own T cells so they are able to recognize and attack cancer. T cells are taken from a patient's blood. Then the gene for a special receptor that binds to a certain protein on the patient's cancer cells is added in the laboratory.
One most import step of CAR-T cell therapy is T cell reengineering, which produce chimeric antigen receptors (CARs) on the surface of the cells. Then these reengineered T cell need to select and collected from others. This is often done by flow cytometry, using protein L, anti-Fab antibodies or target antigens as detection methods. Among these common choices, target antigens are widely considered to be the best option, because it offers high specificity and minimal background staining.
In order to avoid damage to healthy tissues caused by CAR-T cell therapy, the targets must be restricted to tumor cells. However, it is quite difficult to discover an ideal biomarker as an anti-tumor target, which highly expressed on tumor cell surface and rarely expressed on the healthy cell. In a more common situation, the chosen biomarkers express on both tumor cell and healthy ones, with a significant expression level discrimination.
Creative BioMart offers a variety of pre-fluorescent-conjugated and pre-biotinylated recombinant proteins, which are convenient for your cell separation. Featured products are listed below, please contact us for more details or more protein information. We could conjugate specific recombinant proteins according to your custom requirements.
Gene | Cat.No. | Products Name | Source | Species | Tag |
---|---|---|---|---|---|
CD44 | CD44-578H | Recombinant Human CD44, Fc-tagged, Biotinylated | Human Cell | Human | Fc |
CD70 | CD70-892H | Recombinant Human CD70 Protein, Fc-Avi-tagged, Biotinylated | HEK293 | Human | Avi|Fc |
EGFR | EGFR-288H | Recombinant Human EGFR Protein, His-Avi-tagged, Biotinylated | HEK293 | Human | His|Avi |
EGFR-341H | Recombinant Human EGFRvIII Protein, His & Avi-tagged, Biotinylated | HEK293 | Human | His|Avi | |
EGFR-285H | Recombinant Human EGFR, His&Avi-tagged, Biotinylated | HEK293 | Human | His|Avi | |
EGFR-43H | Recombinant Human EGFR(T790M/L858R) protein, Flag-tagged, Biotinylated | Insect Cell | Human | Flag | |
EGFR-284H | Recombinant Human EGFR, His-tagged, Biotinylated | HEK293 | Human | His | |
EGFR-602H | Recombinant Human EGFR, Fc-tagged, Biotinylated | Human Cell | Human | Fc | |
EGFR-42H | Recombinant Human EGFR protein, Flag-tagged, Biotinylated | Insect Cell | Human | Flag | |
EGFR-287H | Recombinant Human EGFR protein, Avi/His-tagged, Biotinylated | HEK293 | Human | Avi|His |
Gene | Cat.No. | Products Name | Source | Species | Tag |
---|---|---|---|---|---|
CEACAM5 | CEACAM5-495H | Recombinant Human CEACAM5 Protein (Met1-Ala685), His-tagged, Biotinylated | HEK293 | Human | His |
EPCAM | EPCAM-572H | Recombinant Human EPCAM Protein, Fc-Avi-tagged, Biotinylated | HEK293 | Human | Avi|Fc |
EPCAM-350H | Recombinant Human EPCAM Protein, His & Avi-tagged, Biotinylated | HEK293 | Human | His|Avi | |
EPCAM-7818H | Recombinant Human EPCAM Protein, Fc-Avi-tagged, Biotinylated | HEK293 | Human | Avi|Fc | |
EPCAM-571H | Recombinant Human EPCAM, Fc-tagged, Biotinylated | Human Cell | Human | Fc | |
EPCAM-418H | Recombinant Human EPCAM Protein (Met1-Lys265), HIgG1 Fc-tagged, Biotinylated | Insect Cell | Human | HIgG1 Fc | |
EPCAM-276H | Recombinant Human EPCAM, His-tagged, Biotinylated | HEK293 | Human | His |
Gene | Cat.No. | Products Name | Source | Species | Tag |
---|---|---|---|---|---|
ERBB2 | ERBB2-360H | Recombinant Human ERBB2 Protein, His & Avi-tagged, Biotinylated | HEK293 | Human | His|Avi |
ERBB2-183H | Recombinant Human ERBB2 Protein, His-Avi-tagged, Biotinylated | HEK293 | Human | His|Avi | |
ERBB2-182H | Recombinant Human ERBB2, His-tagged, Biotinylated | HEK293 | Human | His | |
ERBB2-1110H | Recombinant Human ERBB2 Protein (Met1-Thr652), HlgG1 Fc-tagged, Biotinylated | HEK293 | Human | HlgG1 Fc | |
FOLR1 | FOLR1-031H | Recombinant Human FOLR1 Protein, His-Avi-tagged, Biotinylated | HEK293 | Human | His|Avi |
FOLR1-317M | Recombinant Mouse FOLR1 Protein, His & Avi-tagged, Biotinylated | HEK293 | Mouse | His|Avi | |
Folr1-0630M | Recombinant Mouse Folr1 protein, His-tagged, Biotinylated | HEK293 | Mouse | His | |
GPC3 | GPC3-2247H | Recombinant Human GPC3 Protein, His-Avi-tagged, Biotinylated | HEK293 | Human | His|Avi |
GPC3-619H | Recombinant Human GPC3, Fc-tagged, Biotinylated | Human Cell | Human | Fc |
Gene | Cat.No. | Products Name | Source | Species | Tag |
---|---|---|---|---|---|
IL1RAP | IL1RAP-628H | Recombinant Human IL1RAP, Fc-tagged, Biotinylated | Human Cell | Human | Fc |
KDR | KDR-632H | Recombinant Human KDR Protein, His-Avi-tagged, Biotinylated | HEK293 | Human | His|Avi |
KDR-630H | Recombinant Human KDR, His-tagged, Biotinylated | Human Cell | Human | His | |
KDR-631H | Recombinant Human KDR, Fc-tagged, Biotinylated | Human Cell | Human | Fc | |
KDR-6967H | Recombinant Human KDR Protein, His & Avi-tagged, Biotinylated | HEK293 | Human | His|Avi | |
KDR-58H | Recombinant Human KDR protein, Flag-tagged, Biotinylated | Insect Cell | Human | Flag | |
MET | MET-195H | Recombinant Human MET Protein, His & Avi-tagged, Biotinylated | HEK293 | Human | His|Avi |
MET-64H | Recombinant Human MET protein, Flag-tagged, Biotinylated | Insect Cell | Human | Flag |
Gene | Cat.No. | Products Name | Source | Species | Tag |
---|---|---|---|---|---|
ROR1 | ROR1-1810H | Recombinant Human ROR1 Protein, His-Avi-tagged, Biotinylated | HEK293 | Human | His|Avi |
ROR1-312H | Recombinant Human ROR1 Protein (Gln 30 - Glu 403), Avi-tagged, Biotinylated | HEK293 | Human | Avi | |
ROR1-595H | Recombinant Human ROR1 Protein (Met1-Glu403), Biotinylated | HEK293 | Human | N/A | |
ROR1-1811H | Recombinant Human ROR1 protein, Fc & Avi-tagged, Biotinylated | HEK293 | Human | Avi|Fc | |
ROR1-666H | Recombinant Human ROR1, Fc-tagged, Biotinylated | Human Cell | Human | Fc | |
SLAMF7 | SLAMF7-187H | Recombinant Human SLAMF7 Protein, His-Avi-tagged, Biotinylated | HEK293 | Human | His|Avi |
SLAMF7-688H | Recombinant Human SLAMF7, Fc-tagged, Biotinylated | Human Cell | Human | Fc |
Gene | Cat.No. | Products Name | Source | Species | Tag |
---|---|---|---|---|---|
TNFRSF17 | Tnfrsf17-882M | Recombinant Mouse TNFRSF17 Protein, Fc-Avi-tagged, Biotinylated | HEK293 | Mouse | Avi|Fc |
TNFRSF17-240H | Recombinant Human TNFRSF17 Protein, His-Avi-tagged, Biotinylated | HEK293 | Human | His|Avi | |
TNFRSF17-409H | Recombinant Human TNFRSF17 Protein (Met1-Ala54), His-Fc-tagged, Biotinylated | HEK293 | Human | His|Fc | |
TNFRSF17-984R | Recombinant Rhesus TNFRSF17 Protein (Met1-Ala53), AVI-Fc-tagged, Biotinylated | HEK293 | Rhesus | Avi|Fc | |
TNFRSF17-1827C | Recombinant Cynomolgus TNFRSF17 protein, Fc & Avi-tagged, Biotinylated | HEK293 | Cynomolgus | Avi|Fc | |
TNFRSF17-552H | Recombinant Human TNFRSF17, Fc-tagged, Biotinylated | Human Cell | Human | Fc | |
TNFRSF17-238H | Recombinant Human TNFRSF17 Protein, Fc & Avi-tagged, Biotinylated | HEK293 | Human | Avi|Fc | |
TNFRSF8 | TNFRSF8-434H | Recombinant Human TNFRSF8 Protein (Met1-Lys379), His-tagged, Biotinylated | HEK293 | Human | His |
TNFRSF8-1821H | Recombinant Human TNFRSF8 protein, His & Avi-tagged, Biotinylated | HEK293 | Human | His|Avi |
Gene | Cat.No. | Products Name | Source | Species | Tag |
---|---|---|---|---|---|
CEACAM5 | CEACAM5-665HP | Recombinant Human CEACAM5 protein, Fc-His-tagged, R-PE labeled | HEK293 | Human | Fc-His |
MSLN | MSLN-10625HP | Recombinant Human MSLN protein, Fc-tagged, R-PE labeled | HEK293 | Human | Fc |
MSLN-185HP | Recombinant Human MSLN protein, Fc-tagged, R-PE labeled | HEK293 | Human | Fc | |
MSLN-340HP | Recombinant Human MSLN protein, Fc-tagged, R-PE labeled | HEK293 | Human | Fc | |
MSLN-528HP | Recombinant Human MSLN protein, Fc-tagged, R-PE labeled | HEK293 | Human | Fc | |
MSLN-7350HP | Recombinant Human MSLN protein, Fc-tagged, R-PE labeled | HEK293 | Human | Fc | |
MSLN-8558HP | Recombinant Human MSLN protein, Fc-tagged, R-PE labeled | HEK293 | Human | Fc | |
CA9 | CA9-1544CP | Recombinant Canine CA9 protein, Fc-tagged, R-PE labeled | HEK293 | Canine | Fc |
CA9-890HP | Recombinant Human CA9 protein, Fc-tagged, R-PE labeled | HEK293 | Human | Fc |
Gene | Cat.No. | Products Name | Source | Species | Tag |
---|---|---|---|---|---|
CD226 | CD226-634HA | Recombinant Human CD226 protein, Fc-His-tagged, APC labeled | HEK293 | Human | Fc-His |
CD226-635HA | Recombinant Human CD226 protein, Fc-tagged, APC labeled | HEK293 | Human | Fc | |
Cd226-635MA | Recombinant Mouse Cd226 protein, Fc-His-tagged, APC labeled | HEK293 | Mouse | Fc-His | |
Cd226-8794RA | Recombinant Rat Cd226 protein, Fc-tagged, APC labeled | HEK293 | Rat | Fc | |
CD226-248CA | Recombinant Cynomolgus CD226 protein, Fc-tagged, APC labeled | HEK293 | Cynomolgus | Fc | |
TNFRSF8 | TNFRSF8-1594HA | Recombinant Human TNFRSF8 protein, Fc-tagged, APC labeled | NS0 Cells | Human | Fc |
TNFRSF8-263HA | Recombinant Human TNFRSF8 protein, Fc-tagged, APC labeled | NS0 Cells | Human | Fc | |
TNFRSF8-641HA | Recombinant Human TNFRSF8 protein, Fc-tagged, APC labeled | HEK293 | Human | Fc | |
TNFRSF8-642HA | Recombinant Human TNFRSF8 protein, Fc-His-tagged, APC labeled | HEK293 | Human | Fc-His | |
SPN | Spn-7035MA | Recombinant Mouse Spn protein, Fc-tagged, APC labeled | HEK293 | Mouse | Fc |
Gene | Cat.No. | Products Name | Source | Species | Tag |
---|---|---|---|---|---|
ULBP2 | ULBP2-449HA | Recombinant Human ULBP2 protein, Fc-tagged, APC labeled | HEK293 | Human | Fc |
IL1RAP | IL1RAP-175HA | Recombinant Human IL1RAP protein, Fc-His-tagged, APC labeled | HEK293 | Human | Fc-His |
IL1RAP-627HA | Recombinant Human IL1RAP protein, Fc-tagged, APC labeled | HEK293 | Human | Fc | |
EPCAM | EPCAM-475HA | Recombinant Human EPCAM protein, Fc-tagged, APC labeled | NS0 Cells | Human | Fc |
EPCAM-81HA | Recombinant Human EPCAM protein, Fc-tagged, APC labeled | HEK293 | Human | Fc | |
Epcam-191MA | Recombinant Mouse Epcam protein, Fc-tagged, APC labeled | NS0 Cells | Mouse | Fc | |
Epcam-7481RA | Recombinant Rat Epcam protein, Fc-tagged, APC labeled | HEK293 | Rat | Fc | |
EPCAM-186CA | Recombinant Cynomolgus EPCAM protein, Fc-tagged, APC labeled | HEK293 | Cynomolgus | Fc |
Gene | Cat.No. | Products Name | Source | Species | Tag |
---|---|---|---|---|---|
GPC3 | GPC3-620HA | Recombinant Human GPC3 protein, Fc-tagged, APC labeled | HEK293 | Human | Fc |
Gpc3-120MA | Recombinant Mouse Gpc3 protein, Fc-tagged, APC labeled | HEK293 | Mouse | Fc | |
GPC3-50CA | Recombinant Cynomolgus GPC3 protein, Fc-tagged, APC labeled | HEK293 | Cynomolgus | Fc | |
GPC3-2246HA | Recombinant Human GPC3 protein, His-tagged, APC labeled | Human Cells | Human | His | |
MUC1 | MUC1-342HA | Recombinant Human MUC1 protein, Fc-tagged, APC labeled | HEK293 | Human | Fc |
MUC1-3952HA | Recombinant Human MUC1 protein, Fc-tagged, APC labeled | HEK293 | Human | Fc | |
CA9 | CA9-1544CA | Recombinant Canine CA9 protein, Fc-tagged, APC labeled | HEK293 | Canine | Fc |
CA9-890HA | Recombinant Human CA9 protein, Fc-tagged, APC labeled | HEK293 | Human | Fc |
Gene | Cat.No. | Products Name | Source | Species | Tag |
---|---|---|---|---|---|
PDCD1 | PDCD1-031HA | Recombinant Human PDCD1 protein, MIgG2a Fc-tagged, APC labeled | CHO | Human | MIgG2a Fc |
PDCD1-032HA | Recombinant Human PDCD1 protein, HIgG1 Fc-tagged, APC labeled | CHO | Human | HIgG1 Fc | |
PDCD1-034HA | Recombinant Human PDCD1 protein, mutant HIgG1 Fc-tagged, APC labeled | CHO | Human | mutant HIgG1 Fc-tagged | |
PDCD1-188HA | Recombinant Human PDCD1 protein, Fc-tagged, APC labeled | CHO | Human | Fc | |
PDCD1-189HA | Recombinant Human PDCD1 protein, Fc-tagged, APC labeled | CHO | Human | Fc | |
PDCD1-191HA | Recombinant Human PDCD1 protein, Fc-tagged, APC labeled | CHO | Human | Fc | |
PDCD1-3244HA | Recombinant Human PDCD1 protein, Fc-His-tagged, APC labeled | HEK293 | Human | Fc-His | |
PDCD1-821HA | Recombinant Human PDCD1 protein, Fc-tagged, APC labeled | HEK293 | Human | Fc | |
CD40 | CD40-108HA | Recombinant Human CD40 protein, Fc-tagged, APC labeled | CHO | Human | Fc |
Cd79a | Cd79a-904MA | Recombinant Mouse Cd79a protein, Fc-tagged, APC labeled | HEK293 | Mouse | Fc |
Gene | Cat.No. | Products Name | Source | Species | Tag |
---|---|---|---|---|---|
IL13RA2 | IL13RA2-618HA | Recombinant Human IL13RA2 protein, Fc-tagged, APC labeled | NS0 Cells | Human | Fc |
IL13RA2-765HA | Recombinant Human IL13RA2 protein, Fc-His-tagged, APC labeled | HEK293 | Human | Fc-His | |
IL13RA2-766HA | Recombinant Human IL13RA2 protein, Fc-tagged, APC labeled | HEK293 | Human | Fc | |
Il13ra2-1056MA | Recombinant Mouse Il13ra2 protein, Fc-tagged, APC labeled | NS0 Cells | Mouse | Fc | |
Il13ra2-764MA | Recombinant Mouse Il13ra2 protein, Fc-His-tagged, APC labeled | HEK293 | Mouse | Fc-His | |
Il13ra2-8738RA | Recombinant Rat Il13ra2 protein, Fc-tagged, APC labeled | HEK293 | Rat | Fc | |
CD79B | CD79B-239HA | Recombinant Human CD79B protein, Fc-tagged, APC labeled | HEK293 | Human | Fc |
MMP2 | MMP2-8392HA | Recombinant Human MMP2 protein, GST-tagged, APC labeled | E.coli Cells | Human | GST |
Gene | Cat.No. | Products Name | Source | Species | Tag |
---|---|---|---|---|---|
FOLR1 | FOLR1-1146RA | Recombinant Rat FOLR1 protein, Fc-tagged, APC labeled | HEK293 | Rat | Fc |
FOLR1-1062CA | Recombinant Canine FOLR1 protein, Fc-tagged, APC labeled | HEK293 | Canine | Fc | |
L1CAM | L1CAM-485HA | Recombinant Human L1CAM protein, Fc-tagged, APC labeled | NS0 Cells | Human | Fc |
L1CAM-526HA | Recombinant Human L1CAM protein, His/Fc-tagged, APC labeled | NS0 Cells | Human | His/Fc | |
L1CAM-628HA | Recombinant Human L1CAM protein, Fc-His-tagged, APC labeled | HEK293 | Human | Fc-His | |
VCAM1 | VCAM1-1794MA | Recombinant Human VCAM1 protein, HIgG1 Fc-tagged, APC labeled | CHO | Human | HIgG1 Fc |
VCAM1-71HA | Recombinant Human VCAM1 protein, Fc-tagged, APC labeled | HEK293 | Human | Fc | |
VCAM1-1793MA | Recombinant Mouse VCAM1 protein, MIgG2a Fc-tagged, APC labeled | CHO | Mouse | MIgG2a Fc | |
ROR1 | ROR1-198HA | Recombinant Human ROR1 protein, His-tagged, APC labeled | HEK293 | Human | His |
ROR2 | ROR2-183HA | Recombinant Human ROR2 protein, Fc-tagged, APC labeled | HEK293 | Human | Fc |
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