CD79 is a heterodimeric molecule comprised of an alpha-chain (CD79a) and beta-chain (CD79b). A 37-39 kD type I integral membrane protein CD79b is non-covalently associated with CD79a and cell surface IgM to form the B-cell receptor (BCR) complex. CD79b is
CD79B involved in several pathways and played different roles in them. We selected most pathways CD79B participated on our site, such as B cell receptor signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CD79B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
CD79B has several biochemical functions, for example, protein binding, transmembrane signaling receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CD79B itself. We selected most functions CD79B had, and list some proteins which have the same functions with CD79B. You can find most of the proteins on our site.
CD79B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CD79B here. Most of them are supplied by our site. Hope this information will be useful for your research of CD79B.
SGTA; q8ckf8_yerpe
Lu, D; Jin, JY; et al. POPULATION PHARMACOKINETICS AND EXPOSURE-RESPONSE ASSESSMENT OF ANTI-CD79B ANTIBODY DRUG CONJUGATE IN PATIENTS: INTERIM ANALYSIS RESULTS.. CLINICAL PHARMACOLOGY & THERAPEUTICS 97:S88-S89(2015).
Chang, CH; Wang, Y; et al. Extensive crosslinking of CD22 by epratuzumab triggers BCR signaling and caspase-dependent apoptosis in human lymphoma cells. MABS 7:199-211(2015).
