| Official Full Name | major histocompatibility complex, class I, G |
| Background | HLA-G is a nonclassical MHC class I (MHC-Ib) molecule structurally related to MHC class Ia (HLA-A,B, C). There are seven isoforms of this molecule, including membrane bound HLA-G1, -G2, -G3 and -G4 and soluble HLA-G5, -G6, and -G7. HLA-G is primarily expr |
| Synonyms | HLA-G; major histocompatibility complex, class I, G; HLA G histocompatibility antigen, class I, G; HLA class I histocompatibility antigen, alpha chain G; b2 microglobulin; HLA G antigen; HLA class I molecule; MHC class I antigen G; HLA-G histocompatibility antigen, class I, G; MHC-G |
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|
HLA-G involved in several pathways and played different roles in them. We selected most pathways HLA-G participated on our site, such as Endocytosis, Phagosome, Cell adhesion molecules (CAMs), which may be useful for your reference. Also, other proteins which involved in the same pathway with HLA-G were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Endocytosis | BIN1; ARRB2; SNX12; PRKCI; NTRK1; EHD1; SNX1; SNX2; PIP5K1C; STAM2 |
| Phagosome | FCGR1A; SEC61G; ATP6V0A1; BLB2; TUBA4L; BMA1; HLA-DRB5; TUBA1L2; HLA-DOA; ITGB1B.2 |
| Cell adhesion molecules (CAMs) | CLDN5; HLA-DRB5; OCLN; MADCAM1; BMA1; ITGAL; VTCN1; ITGAV; NEGR1; CNTNAP2 |
| Antigen processing and presentation | H2-Q10; KLRC4; KIR2DL1; KLRC3; PSME1; HLA-B; KLRC1; KIR3DL2; H2-AA; KLRC2 |
| Natural killer cell mediated cytotoxicity | ZAP70; PLCG2; SH3BP2; IFNA6; FCGR4; MAPK3; PRKCA; HLA-G; PIK3R5; KLRA8 |
| Type I diabetes mellitus | HLA-DRA; HLA-DRB4; LTA; HLA-DQA1; HLA-DMB; HSPD1; HLA-DQA2; IL1B; HLA-DRB5; ICA1 |
| HTLV-I infection | TNF; CD40; CANX; IL15RA; PIK3R5; CD3D; WNT7B; PIK3R3; RB1; ATM |
| Herpes simplex infection | MHC2DEB; HCFC1B; TAP2; SRSF1A; IL12A; MHC2A; HLA-DRB5; BLB2; RNASEL; HCFC1 |
| Epstein-Barr virus infection | HDAC5; PRKACB; TRAF3; RBPJ; TYK2; PLCG1; YWHAH; PSMC4; PIK3R1; IRF3 |
| Viral carcinogenesis | UBE3A; HIST1H4H; HIST1H2BA; IRF7; HIST1H4D; TBP; TRADD; RBL2; SCRIB; HIST1H4N |
| Autoi | IFNA14; HLA-DRB5; TPO; TG; IFNA4; Ifna11; Ifna15; HLA-DRB3; Fasl; CD40 |
| ne thyroid disease | IFNA5; GZMB; HLA-DQB1; TSHB; HLA-DRB5; IFNA4; PRF1; FAS; CD86; CD40 |
| Allograft rejection | HLA-DRA; Fasl; IL4; HLA-DQA1; CD28; H2-AB1; HLA-DRB1; H2-AA; HLA-DPB1; MICA |
| Graft-versus-host disease | FASLG; HLA-DOA; KIR3DL1; KLRD1; KIR2DL3; IFNG; HLA-A; Fasl; KIR2DL1; HLA-F |
| Viral myocarditis | CD28; H2-AA; Casp3; CD80; EIF4G3; BID; EIF4G2; CASP8; ITGB2; HLA-C |
HLA-G has several biochemical functions, for example, peptide antigen binding, protein homodimerization activity, receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HLA-G itself. We selected most functions HLA-G had, and list some proteins which have the same functions with HLA-G. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| peptide antigen binding | HLA-DQA1; HLA-DPB1; MHC1UEA; TAPBP; HLA-DRB1; HLA-B; TAP1; MR1; HLA-A; AZGP1 |
| protein homodimerization activity | CISD2; ADD1; DARS2; TFRC; CTBP1; HNF1A; FAM109A; FLT3; GIMAP7; GRPEL1 |
| receptor binding | CD72; LRP6; SSTR3; PVRL3B; CD276; RIPK2; HIST2H3C2; PTK6; LGI1; WIPI1 |
HLA-G has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HLA-G here. Most of them are supplied by our site. Hope this information will be useful for your research of HLA-G.
LILRB1; HLA-A
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