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FGF2

  • Official Full Name

    Fibroblast Growth Factor 2 (basic)

  • Background

    roblast growth factors, or FGFs, are a family of growth factors involved in angiogenesis, wound healing, and embryonic development. The FGFs are heparin-binding proteins and interactions with cell-surface associated heparan sulfate proteoglycans have been shown to be essential for FGF signal transduction. FGFs are key players in the processes of proliferation and differentiation of wide variety of cells and tissues.

  • Synonyms

    FGF2; fibroblast growth factor 2 (basic); BFGF; FGFB; HBGF-2; heparin-binding growth factor 2; prostatropin; OTTHUMP00000037513; basic fibroblast growth factor bFGF; Fgf-2;
    • Type:
    • Chromatography Reagents
    • Native Proteins
    • Recombinant Proteins
    • GMP Proteins
    • Antibody
    • Cell & Tissue Lysates
    • Transfected Stable Cell Lines
    • Protein Pre-coupled Magnetic Beads
    • Species :
    • Bovine
    • Bovine/Porcine
    • Cattle
    • Chicken
    • Human
    • Mouse
    • Pig
    • Porcine
    • Rabbit
    • Rat
    • Zebrafish
    • Source :
    • Barley Grain
    • Bovine
    • Bovine brain
    • Bovine Pituitary
    • CHO
    • CHO-K1
    • E. coli
    • E.coli
    • HEK293
    • HEK293T
    • Hordeum Vulgare
    • Human Cell
    • Human cells
    • Insect Cell
    • Mammalian Cell
    • Mouse
    • Oryza Sativa
    • Sf21 Insect Cell
    • Wheat Germ
    • yeast
    • Yeast
    • Tag :
    • Ala
    • Avi
    • His
    • Biotin
    • C
    • Myc
    • DDK
    • ERHV|His
    • GST
    • HIS
    • His (Fc)
    • His(N
    • ter)
    • His|S
    • SUMO
    • MBP
    • MYC
    • Myc|DDK
    • N/A
    • N
    • Strep II
    • Tag Free
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    bFGF-10A Recombinant bFGF agarose fast flow N/A
    Bovine FGF2-34B Active Native Bovine bFGF Bovine Pituitary N/A
    Bovine FGF2-650B Recombinant Bovine Fibroblast Growth Factor 2 Bovine N/A
    Bovine FGF2-018E Recombinant Bovine FGF2 protein E.coli N/A
    Bovine FGF2-1182B Recombinant Bovine Fibroblast Growth Factor 2 (basic) E.coli N/A
    Bovine FGF2-4381B Recombinant Bovine FGF2 Protein Yeast N/A
    Bovine FGF2-12B Recombinant Bovine FGF2 Protein E.coli N/A
    Bovine FGF2-40B Native Bovine FGF2 Protein Bovine brain N/A
    Bovine FGF2-399F Recombinant Bovine FGF2 Protein (146 aa) E.coli
    Bovine/Porcine FGF2-06B Recombinant Bovine/Porcine FGF2 Protein E.coli
    Bovine/Porcine FGF2-07B Recombinant Bovine/Porcine FGF2 Protein E.coli
    Cattle FGF2-2185C Recombinant Cattle FGF2 Protein, His-tagged E.coli N-His
    Cattle FGF2-2186C Recombinant Cattle FGF2 Protein, His-tagged E.coli N-His
    Chicken FGF2-6983C Recombinant Chicken FGF2 Mammalian Cell His
    Chicken FGF2-6739C Recombinant Chicken FGF2 protein, His-tagged E.coli His
    Human FGF2-15H Recombinant Human FGF2 Protein, Pre-aliquoted E.coli
    Human FGF2-022E Active Recombinant Human FGF2 (143-288aa), Ala tagged E.coli N/A
    Human FGF2-5403H Recombinant Human FGF2 protein, His-tagged Yeast His
    Human FGF2-178HG GMP Recombinant Human FGF2 protein CHO
    Human FGF2-1487H Recombinant Human FGF2 Protein, His-tagged E.coli N-His
    Human FGF2-567H Recombinant Human FGF2 protein E.coli N/A
    Human FGF2-2120H Recombinant Human FGF2 protein, Avi & His-tagged, Biotinylated E.coli Avi & His
    Human FGF2-41H Recombinant Human FGF2 protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human FGF2-108HG GMP Recombinant Human FGF2 Protein E.coli N/A
    Human FGF2-22H Recombinant Human FGF2 protein, GST-tagged Wheat Germ GST
    Human FGF2-81H Recombinant Human FGF2 Protein E.coli
    Human DMABT-H18566 Mouse Anti-FGF2 Monoclonal Antibody Mouse Biotin
    Human FGF2-001H Recombinant Human FGF2 Protein, His-tagged E.coli His
    Human FGF2-2784H Recombinant Human FGF2 protein, His-tagged E.coli His
    Human FGF2-82H Recombinant Human FGF2 Protein E.coli
    Human FGF2-022H Recombinant Human FGF2 Protein E.coli N/A
    Human FGF2-1H Active Recombinant Human FGF basic protein E.coli N/A
    Human FGF2-155H Recombinant Human FGF2 Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
    Human FGF2-01H Recombinant Heat Stable Human FGF2 Protein, Animal Free Human cells
    Human FGF2-12H Active Recombinant Human FGF2 E.coli N/A
    Human FGF2-19H Active Recombinant Human FGF2 protein, ERHV-His-tagged Barley Grain ERHV/His
    Human FGF2-044H Recombinant Human FGF2 Protein E. coli
    Human FGF2-122H Recombinant Human FGF2 Protein E.coli
    Human FGF2-730H Active Recombinant Human FGF2, Ala-tagged E.coli Ala
    Human FGF2-169H Active Recombinant Human FGF2 Insect Cell N/A
    Human FGF2-2910H Recombinant Human FGF2 protein, His-SUMO-tagged E.coli His-SUMO
    Human FGF2-123H Recombinant Human FGF2 Protein E.coli
    Human FGF2-91H Recombinant Human FGF2,His-tagged Insect Cell HIS
    Human FGF2-638HCL Recombinant Human FGF2 cell lysate Insect Cell N/A
    Human FGF2-179HG Active GMP Recombinant Human FGF2 protein HEK293 N/A
    Human FGF2-402F Recombinant Human FGF2 Protein (145 aa) E.coli
    Human FGF2-590H Recombinant Human FGF2 protein E.coli
    Human FGF2-8856H Active Recombinant Human Fibroblast Growth Factor 2 (basic) Hordeum Vulgare N/A
    Human FGF2-01HG Active GMP Recombinant Human bFGF Protein CHO-K1
    Human FGF2-20H Recombinant Human FGF2 Protein (Formulation I- Animal Free-Lyophilized, 134-288, 154 amino acid) E.coli
    Human FGF2-09H Recombinant Human FGF2 Protein E.coli
    Human FGF2-11H Recombinant Human Fibroblast Growth Factor-basic E.coli N/A
    Human FGF2-14H Recombinant Human FGF2 Protein E.coli
    Human FGF2-21H Recombinant Human FGF2 Protein (Formulation I- Animal Free-Ready-to-Use, 134-288, 154 amino acid) E.coli
    Human FGF2-77H Recombinant Active Human FGF2 Protein, His-tagged(N-ter) E.coli His(N-ter)
    Human FGF2-10H Recombinant Human FGF2 Protein E.coli
    Human FGF2-133H Recombinant Human FGF2 Protein E.coli
    Human FGF2-26551TH Native Human FGF2 E.coli N/A
    Human FGF2-130H Recombinant Human FGF2 Protein E.coli
    Human FGF2-16H Recombinant Human FGF2 Protein, Animal Free Human cells
    Human FGF2-039H Recombinant Human FGF2 Protein E.coli
    Human FGF2-13H Active Recombinant Human FGF2 Protein, Biotinylated E.coli N/A
    Human FGF2-1486H Recombinant Human FGF2 Protein, His-tagged E.coli N-His
    Human FGF2-400F Recombinant Human FGF2 Protein (154 aa) E.coli
    Human FGF2-18H Recombinant Human FGF2 Protein (143-288aa), Non-tagged E.coli Tag Free
    Human FGF2-198H Recombinant Human FGF2 protein, His/S-tagged E.coli His/S
    Human FGF2-1488H Recombinant Human FGF2 Protein, His-tagged E.coli N-His
    Human FGF2-25H Recombinant Human FGF2 Protein (Formulation I- Carrier Free-Lyophilized, 134-288, 154 amino acid) E.coli
    Human DMABT-H18565 Mouse Anti-FGF2 Monoclonal Antibody Mouse N/A
    Human FGF2-4345HG GMP Recombinant Human FGF2 protein E.coli N/A
    Human FGF2-1380H Recombinant Human FGF2 protein, MBP&His-Avi-tagged, Biotinylated E.coli MBP&His-Avi
    Human FGF2-24H Recombinant Human FGF2 Protein (Formulation II-Carrier-Lyophilized, 134-288, 154 amino acid) E.coli
    Human FGF2-401F Recombinant Human FGF2 Protein (146 aa) E.coli
    Human FGF2-5H Recombinant Human Basic Fibroblast Growth Factor yeast N/A
    Human FGF2-33HG Recombinant Human FGF2 Protein (Pro143-Ser288), GMP Grade, Animal-Free E.coli
    Human FGF2-105H Recombinant Human Basic Fibroblast Growth Factor (rDNA derived) Reference standard E.coli N/A
    Human FGF2-23H Recombinant Human FGF2 Protein (Formulation I- Carrier Free-Ready-to-Use, 134-288, 154 amino acid) E.coli
    Human FGF2-014O Recombinant Human FGF2 Oryza Sativa N/A
    Human FGF2-17H Recombinant Human FGF2 Protein (Formulation II-Carrier-Ready-to-Use, 134-288, 154 amino acid) E.coli
    Human FGF2-27596TH Recombinant Human FGF2 N/A
    Human FGF2-28HG Recombinant Human FGF2 Protein, GMP Grade, Animal-Free E.coli
    Human FGF2-27258TH Recombinant Human FGF2, His-tagged His
    Human FGF2-8499H Active Recombinant Human FGF2, His-tagged Sf21 Insect Cell His
    Human FGF2-482H Recombinant Human FGF2, None tagged E.coli N/A
    Human FGF2-293H Recombinant Human FGF2, StrepII-tagged Human Cell Strep II
    Human FGF2-678H Recombinant Human Fibroblast Growth Factor 2 (basic) (aa 146) E.coli N/A
    Mouse Fgf2-79M Recombinant Active Mouse FGF2 Protein, His-tagged(N-ter) E.coli His(N-ter)
    Mouse FGF2-3232M-B Recombinant Mouse FGF2 Protein Pre-coupled Magnetic Beads HEK293
    Mouse Fgf2-01M Active GMP Recombinant Mouse Fgf2 Protein, His-Tagged E.coli His
    Mouse Fgf2-199M Recombinant Mouse Fgf2 protein, His/S-tagged E.coli His/S
    Mouse Fgf2-13M Recombinant Mouse Fgf2 Protein E.coli
    Mouse FGF2-3232M Recombinant Mouse FGF2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Mouse Fgf2-680M Recombinant Mouse Fibroblast Growth Factor 2 E.coli N/A
    Mouse Fgf2-398F Recombinant Mouse Fgf2 Protein (146 aa) E.coli
    Mouse Fgf2-5230M Recombinant Mouse Fgf2 protein, His-tagged E.coli His
    Mouse FGF2-83M Recombinant Mouse FGF2 Protein E.coli
    Mouse Fgf2-7206M Recombinant Mouse Fgf2 Protein E.coli
    Mouse Fgf2-664M Recombinant Mouse Fibroblast Growth Factor 2 Mouse N/A
    Mouse Fgf2-059M Recombinant Mouse Fgf2 Protein E.coli
    Mouse Fgf2-12M Recombinant Mouse Fgf2 protein E.coli N/A
    Mouse Fgf2-060M Recombinant Mouse Fgf2 Protein E.coli
    Mouse FGF2-5847M Recombinant Mouse FGF2 Protein Mammalian Cell His
    Mouse Fgf2-829M Active Recombinant Mouse Fgf2 Protein, His-tagged E.coli His
    Mouse Fgf2-061M Recombinant Mouse Fgf2 Protein E.coli
    Mouse Fgf2-062M Recombinant Mouse Fgf2 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Mouse FGF2-1968M Recombinant Mouse FGF2 Protein E.coli N/A
    Pig FGF2-929P Recombinant Pig FGF2 Protein, His-tagged E.coli N-His
    Pig FGF2-78P Recombinant Active Pig FGF2 Protein, His-tagged(N-ter) E.coli His(N-ter)
    Porcine FGF2-01P Active GMP Recombinant Porcine FGF2 Protein, His-Tagged E.coli His
    Rabbit FGF2-4387R Recombinant Rabbit FGF2 Protein Yeast N/A
    Rabbit FGF2-2785R Recombinant Rabbit FGF2 protein, His-tagged E.coli His
    Rat FGF2-1988R Recombinant Rat FGF2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Rat FGF2-84R Recombinant Rat FGF2 Protein E.coli
    Rat Fgf2-200R Recombinant Rat Fgf2 protein, His/S-tagged E.coli His/S
    Rat Fgf2-397F Recombinant Rat Fgf2 Protein (146 aa) E.coli
    Rat Fgf2-1489R Recombinant Rat Fgf2 Protein, His-tagged E.coli N-His
    Rat FGF2-1988R-B Recombinant Rat FGF2 Protein Pre-coupled Magnetic Beads HEK293
    Rat FGF2-1967R Recombinant Rat FGF2 Protein E.coli N/A
    Rat Fgf2-40R Recombinant Rat Fgf2 protein E.coli N/A
    Rat FGF2-2331R Recombinant Rat FGF2 Protein Mammalian Cell His
    Zebrafish fgf2-08Z Recombinant Zebrafish fgf2 Protein E.coli
    Zebrafish FGF2-12089Z Recombinant Zebrafish FGF2 Mammalian Cell His
    • Involved Pathway
    • Protein Function
    • Interacting Protein
    • FGF2 Related Articles
    • FGF2 Related Research Area
    • FGF2 Related Signal Pathway

    FGF2 involved in several pathways and played different roles in them. We selected most pathways FGF2 participated on our site, such as MAPK signaling pathway, Ras signaling pathway, Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with FGF2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    MAPK signaling pathwayGRB2B;MAPKAPK3;PPM1A;MAP3K5;FGF2;RASA2;MEF2CA;MRAS;PDGFRB
    Ras signaling pathwayKIT;PRKCB;PLA1A;GNB4;PLA2G2F;PLA2G2E;GNG13;FGF8;FGFR2
    Rap signaling pathwayRRAS;FLT4;PRKCA;INSR;FGFR3;Pdgfa&Pdgfb;KLK1B4;IGF1;FGF4
    PIK-Akt signaling pathwayPIK3R5;COL6A5;PRKAA1;GH1;SPP1;IL3;PIK3R3;GH2;YWHAZ
    Signaling pathways regulating pluripotency of stem cellsAPC;SMAD9;KLF4;ESX1;Fzd4;FZD8;WNT3A;NRAS;IGF1R
    Regulation of actin cytoskeletonCDC42;ROCK2;GSNA;RAC3A;FGFR2;PDGFC;ACTG1;FGF19;PIP5KL1
    Pathways in cancerCDC42;PLEKHG5;RAC2;RUNX1;PLCB4;EPAS1;PRKACG;TGFB2;RALBP1
    Proteoglycans in cancerWNT7B;WNT3A;WNT1;HOXD10;KRAS;PDPK1;CD44;IGF2;PLAUR
    MelanomaPDGFA;MAP2K2;FGFR1;MET;FGF19;PDGFC;PTEN;FGF3;IGF1R

    FGF2 has several biochemical functions, for example, chemoattractant activity, cytokine activity, fibroblast growth factor receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FGF2 itself. We selected most functions FGF2 had, and list some proteins which have the same functions with FGF2. You can find most of the proteins on our site.

    Function Related Protein
    chemoattractant activityCCL16;NTF3;SCG2;CCL5;CXCL12A;SAA3;PDGFB;LGALS3;FGF8
    cytokine activityIFNA16;CSF3;CER1;GM13288;GM13285;C1QTNF4;GDF10B;SECTM1;GDF7
    fibroblast growth factor receptor bindingFRS2;FGF18A;FGF9;FGF8B;FGF10B;FGF2;FGF6;FGF16;FGF1
    growth factor activityANGPTL3;IL8L2;MDKB;NDP;IL10;INHBAB;FBRS;LEFTY2;IL4
    heparin bindingNAV2;PCOLCE;MSTN;PTPRF;FGFRL1;LPA;PLA2G5;SERPIND1;TGFBR3
    ligand-dependent nuclear receptor transcription coactivator activityTADA3;NCOA3;HMGA1-RS1;AASS;USP22;ZCCHC12;BUD31;MED17;CALCOCO1
    protein bindingTRPC4;SMIM3;CCDC137;GGACT;NCAPH2;TEAD4;SPON2;ZAP70;WAC

    FGF2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FGF2 here. Most of them are supplied by our site. Hope this information will be useful for your research of FGF2.

    FGFR1; FGFR2; FGFBP1; chondroitin sulfate; ssr; DCN; FGFR1; FGFR2; q6dtl8_bovin; ANOS1

    Correa, D; Somoza, RA; et al. Sequential exposure to fibroblast growth factors (FGF) 2, 9 and 18 enhances hMSC chondrogenic differentiation. OSTEOARTHRITIS AND CARTILAGE 23:443-453(2015).
    Bohnsack, RN; Warejcka, DJ; et al. Expression of Insulin-Like Growth Factor 2 Receptor in Corneal Keratocytes During Differentiation and in Response to Wound Healing. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 55:7697-7708(2014).
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