FGF2

  • Official Full Name

    Fibroblast Growth Factor 2 (basic)

  • Overview

    roblast growth factors, or FGFs, are a family of growth factors involved in angiogenesis, wound healing, and embryonic development. The FGFs are heparin-binding proteins and interactions with cell-surface associated heparan sulfate proteoglycans have been shown to be essential for FGF signal transduction. FGFs are key players in the processes of proliferation and differentiation of wide variety of cells and tissues.
  • Synonyms

    FGF2; fibroblast growth factor 2 (basic); BFGF; FGFB; HBGF-2; heparin-binding growth factor 2; prostatropin; OTTHUMP00000037513; basic fibroblast growth factor bFGF; Fgf-2;

  • Recombinant Proteins
  • GMP Proteins
  • Cell & Tissue Lysates
  • Antibody
  • Transfected Stable Cell Lines
  • Native Proteins
  • Protein Pre-coupled Magnetic Beads
  • Chromatography Reagents
  • Bovine
  • Bovine/Porcine
  • Cattle
  • Chicken
  • Human
  • Mouse
  • Pig
  • Porcine
  • Rabbit
  • Rat
  • Zebrafish
  • Barley Grain
  • Bovine
  • Bovine brain
  • Bovine Pituitary
  • CHO
  • CHO-K1
  • E.coli
  • HEK293
  • HEK293T
  • Hordeum Vulgare
  • Human Cell
  • Human cells
  • Insect Cell
  • Mammalian Cell
  • Mouse
  • Oryza Sativa
  • Sf21 Insect Cell
  • Wheat Germ
  • yeast
  • Yeast
  • Ala
  • Avi
  • His
  • Biotin
  • C
  • Myc
  • DDK
  • ERHV|His
  • GST
  • HIS
  • His (Fc)
  • His(N
  • ter)
  • His|S
  • SUMO
  • MBP
  • MYC
  • Myc|DDK
  • N/A
  • N
  • Strep II
  • Tag Free
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human FGF2-022E Active Recombinant Human FGF2 (143-288aa), Ala tagged E.coli N/A
Human FGF2-8499H Active Recombinant Human FGF2, His-tagged Sf21 Insect Cell His
Human FGF2-12H Active Recombinant Human FGF2 E.coli N/A
Human FGF2-1H Active Recombinant Human FGF basic protein E.coli N/A
Human FGF2-730H Active Recombinant Human FGF2, Ala-tagged E.coli Ala
Human FGF2-19H Active Recombinant Human FGF2 protein, ERHV-His-tagged Barley Grain ERHV/His
Human FGF2-169H Active Recombinant Human FGF2 Insect Cell N/A
Human FGF2-8856H Active Recombinant Human Fibroblast Growth Factor 2 (basic) Hordeum Vulgare N/A
Human FGF2-179HG Active GMP Recombinant Human FGF2 protein HEK293 N/A
Human FGF2-13H Active Recombinant Human FGF2 Protein, Biotinylated E.coli N/A Pro143-Ser288
Human FGF2-01HG Active GMP Recombinant Human bFGF Protein CHO-K1
Human FGF2-11H Recombinant Human Fibroblast Growth Factor-basic E.coli N/A
Human FGF2-91H Recombinant Human FGF2,His-tagged Insect Cell HIS
Human FGF2-482H Recombinant Human FGF2 protein(Pro143-Ser288) E.coli N/A Pro143-Ser288
Human FGF2-567H Recombinant Human FGF2 protein E.coli N/A 147
Human FGF2-293H Recombinant Human FGF2, StrepII-tagged Human Cell Strep II 2-288, 287 a.a.
Human FGF2-590H Recombinant Human FGF2 protein E.coli 146
Human FGF2-678H Recombinant Human Fibroblast Growth Factor 2 (basic) (aa 146) E.coli N/A
Human FGF2-22H Recombinant Human FGF2 protein, GST-tagged Wheat Germ GST
Human FGF2-198H Recombinant Human FGF2 protein, His/S-tagged E.coli His/S
Human FGF2-41H Recombinant Human FGF2 protein, MYC/DDK-tagged HEK293 Myc/DDK
Human FGF2-5H Active Recombinant Human Basic Fibroblast Growth Factor yeast N/A
Human FGF2-2784H Recombinant Human FGF2 protein, His-tagged E.coli His Phe159~Ser288
Human FGF2-014O Recombinant Human FGF2 Oryza Sativa N/A
Human FGF2-27596TH Recombinant Human FGF2 N/A
Human FGF2-27258TH Recombinant Human FGF2, His-tagged His
Human FGF2-638HCL Recombinant Human FGF2 cell lysate Insect Cell N/A
Human DMABT-H18566 Mouse Anti-FGF2 Monoclonal Antibody Mouse Biotin
Human FGF2-105H Recombinant Human Basic Fibroblast Growth Factor (rDNA derived) Reference standard E.coli N/A
Human DMABT-H18565 Mouse Anti-FGF2 Monoclonal Antibody Mouse N/A
Human FGF2-108HG Active GMP Recombinant Human FGF2 Protein E.coli N/A
Human FGF2-022H Active Recombinant Human FGF2 Protein E.coli N/A
Human FGF2-26551TH Native Human FGF2 E.coli N/A
Human FGF2-155H Recombinant Human FGF2 Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
Human FGF2-001H Recombinant Human FGF2 Protein, His-tagged E.coli His 134-288
Human FGF2-1486H Recombinant Human FGF2 Protein, His-tagged E.coli N-His Pro10-Ser155
Human FGF2-4345HG GMP Recombinant Human FGF2 protein E.coli N/A 147
Human FGF2-044H Active Recombinant Human FGF2 Protein E.coli
Human FGF2-15H Active Recombinant Human FGF2 Protein, Pre-aliquoted E.coli Pro143-Ser288
Human FGF2-1488H Recombinant Human FGF2 Protein, His-tagged E.coli N-His Pro143-Ser288
Human FGF2-5403H Recombinant Human FGF2 protein, His-tagged Yeast His 143-288aa
Human FGF2-2910H Recombinant Human FGF2 protein, His-SUMO-tagged E.coli His-SUMO 143-288aa
Human FGF2-1487H Recombinant Human FGF2 Protein, His-tagged E.coli N-His Pro143-Ser288
Human FGF2-1380H Recombinant Human FGF2 protein, MBP&His-Avi-tagged, Biotinylated E.coli MBP&His-Avi 143-288aa
Human FGF2-2120H Recombinant Human FGF2 protein, Avi & His-tagged, Biotinylated E.coli Avi & His Pro 143 - Ser 288
Human FGF2-039H Recombinant Human FGF2 Protein E.coli 822
Human FGF2-10H Recombinant Human FGF2 Protein E.coli 154 aa
Human FGF2-178HG Active GMP Recombinant Human FGF2 protein CHO
Human FGF2-81H Active Recombinant Human FGF2 Protein E.coli
Human FGF2-18H Active Recombinant Human FGF2 Protein (143-288aa), Non-tagged E.coli Tag Free 143-288 aa
Human FGF2-16H Active Recombinant Human FGF2 Protein, Animal Free Human cells 154 aa
Human FGF2-77H Recombinant Active Human FGF2 Protein, His-tagged(N-ter) E.coli His(N-ter)
Human FGF2-82H Active Recombinant Human FGF2 Protein E.coli
Human FGF2-14H Active Recombinant Human FGF2 Protein E.coli 154 aa
Human FGF2-400F Active Recombinant Human FGF2 Protein (154 aa) E.coli 154
Human FGF2-09H Recombinant Human FGF2 Protein E.coli 145 aa
Human FGF2-01H Active Recombinant Heat Stable Human FGF2 Protein, Animal Free Human cells 154 aa
Human FGF2-133H Recombinant Human FGF2 Protein E.coli Pro143-Ser288
Human FGF2-25H Active Recombinant Human FGF2 Protein (Formulation I- Carrier Free-Lyophilized, 134-288, 154 amino acid) E.coli 134-288, 154 amino acid
Human FGF2-130H Recombinant Human FGF2 Protein E.coli
Human FGF2-122H Recombinant Human FGF2 Protein E.coli
Human FGF2-401F Active Recombinant Human FGF2 Protein (146 aa) E.coli 146
Human FGF2-24H Active Recombinant Human FGF2 Protein (Formulation II-Carrier-Lyophilized, 134-288, 154 amino acid) E.coli 134-288, 154 amino acid
Human FGF2-33HG Active Recombinant Human FGF2 Protein (Pro143-Ser288), GMP Grade, Animal-Free E.coli Pro143-Ser288
Human FGF2-123H Recombinant Human FGF2 Protein E.coli
Human FGF2-23H Active Recombinant Human FGF2 Protein (Formulation I- Carrier Free-Ready-to-Use, 134-288, 154 amino acid) E.coli 134-288, 154 amino acid
Human FGF2-3018H Recombinant Human FGF2 Protein (Pro143-Ser288), C-His tagged E.coli C-His Pro143-Ser288
Human FGF2-17H Active Recombinant Human FGF2 Protein (Formulation II-Carrier-Ready-to-Use, 134-288, 154 amino acid) E.coli 134-288, 154 amino acid
Human FGF2-402F Active Recombinant Human FGF2 Protein (145 aa) E.coli 145
Human FGF2-28HG Recombinant Human FGF2 Protein, GMP Grade, Animal-Free E.coli
Human FGF2-20H Active Recombinant Human FGF2 Protein (Formulation I- Animal Free-Lyophilized, 134-288, 154 amino acid) E.coli 134-288, 154 amino acid
Human FGF2-543H Active Recombinant Human FGF2 Protein E.coli Tag Free
Human FGF2-21H Active Recombinant Human FGF2 Protein (Formulation I- Animal Free-Ready-to-Use, 134-288, 154 amino acid) E.coli 134-288, 154 amino acid
Human FGF2-3017H Recombinant Human FGF2 Protein (Pro143-Ser288, Cys211Ser, Cys229Ser), N-SUMO tagged E.coli N-SUMO Pro143-Ser288, Cys211Ser, Cys229Ser
Human FGF2-94H Active Recombinant Human FGF2 Protein (Ala135-Ser288), N-His tagged, Animal-free, Carrier-free E.coli N-His Ala135-Ser288
Mouse Fgf2-829M Active Recombinant Mouse Fgf2 protein(Ala11-Ser154), His-tagged E.coli N-His Ala11-Ser154
Mouse Fgf2-01M Active GMP Recombinant Mouse Fgf2 Protein, His-Tagged E.coli His
Mouse Fgf2-664M Recombinant Mouse Fibroblast Growth Factor 2 Mouse N/A
Mouse Fgf2-680M Recombinant Mouse Fibroblast Growth Factor 2 E.coli N/A
Mouse Fgf2-199M Recombinant Mouse Fgf2 protein, His/S-tagged E.coli His/S
Mouse Fgf2-12M Recombinant Mouse Fgf2 protein E.coli N/A 146
Mouse FGF2-5847M Recombinant Mouse FGF2 Protein Mammalian Cell His
Mouse Fgf2-5230M Recombinant Mouse Fgf2 protein, His-tagged E.coli His 10-154aa
Mouse Fgf2-544M Active Recombinant Mouse Fgf2 Protein E.coli Tag Free
Mouse Fgf2-060M Active Recombinant Mouse Fgf2 Protein E.coli
Mouse Fgf2-061M Active Recombinant Mouse Fgf2 Protein E.coli
Mouse Fgf2-79M Recombinant Active Mouse FGF2 Protein, His-tagged(N-ter) E.coli His(N-ter)
Mouse FGF2-1968M Recombinant Mouse FGF2 Protein E.coli N/A
Mouse Fgf2-062M Recombinant Mouse Fgf2 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse Fgf2-4025M Recombinant Mouse Fgf2 Protein (Pro143-Ser288), C-His tagged E.coli C-His Pro143-Ser288
Mouse Fgf2-13M Recombinant Mouse Fgf2 Protein E.coli
Mouse Fgf2-25M Active Recombinant Mouse Fgf2 Protein (Ala11-Ser154), N-His tagged, Animal-free, Carrier-free E.coli N-His Ala11-Ser154
Mouse Fgf2-7206M Active Recombinant Mouse Fgf2 Protein E.coli
Mouse Fgf2-5419M Recombinant Mouse Fgf2 Protein (Met1-Ser154) E.coli Tag Free Met1-Ser154
Mouse Fgf2-059M Recombinant Mouse Fgf2 Protein E.coli
Mouse FGF2-3232M-B Recombinant Mouse FGF2 Protein Pre-coupled Magnetic Beads HEK293
Mouse FGF2-3232M Recombinant Mouse FGF2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Fgf2-398F Active Recombinant Mouse Fgf2 Protein (146 aa) E.coli 146
Mouse FGF2-83M Active Recombinant Mouse FGF2 Protein E.coli
Rat Fgf2-40R Recombinant Rat Fgf2 protein E.coli N/A 146
Rat Fgf2-200R Recombinant Rat Fgf2 protein, His/S-tagged E.coli His/S
Rat FGF2-2331R Recombinant Rat FGF2 Protein Mammalian Cell His
Rat FGF2-1988R Recombinant Rat FGF2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat Fgf2-397F Active Recombinant Rat Fgf2 Protein (146 aa) E.coli 146
Rat Fgf2-595R Active Recombinant Rat Fgf2 Protein E.coli Tag Free
Rat FGF2-1967R Recombinant Rat FGF2 Protein E.coli N/A
Rat Fgf2-1489R Recombinant Rat Fgf2 Protein, His-tagged E.coli N-His Pro10-Ser154
Rat Fgf2-6841R Recombinant Rat Fgf2 Protein (Ala11-Ser154) E.coli Tag Free Ala11-Ser154
Rat FGF2-84R Active Recombinant Rat FGF2 Protein E.coli
Rat FGF2-1988R-B Recombinant Rat FGF2 Protein Pre-coupled Magnetic Beads HEK293
Rabbit FGF2-2785R Recombinant Rabbit FGF2 protein, His-tagged E.coli His Phe26~Ala153
Rabbit FGF2-6755R Recombinant Rabbit FGF2 protein, His-SUMO-tagged E.coli N-His-SUMO 1-137aa
Rabbit FGF2-4387R Recombinant Rabbit FGF2 Protein Yeast N/A 145aa
Bovine FGF2-40B Active Native Bovine FGF2 Protein Bovine brain N/A
Bovine FGF2-019B Active Recombinant Bovine FGF2 protein, His-tagged E.coli His Pro10~Ser155
Bovine FGF2-34B Active Native Bovine bFGF Bovine Pituitary N/A
Bovine FGF2-650B Recombinant Bovine Fibroblast Growth Factor 2 Bovine N/A
Bovine FGF2-018E Recombinant Bovine FGF2 protein E.coli N/A 147
Bovine FGF2-1182B Recombinant Bovine Fibroblast Growth Factor 2 (basic) E.coli N/A
Bovine FGF2-4381B Recombinant Bovine FGF2 Protein Yeast N/A 145aa
Bovine FGF2-12B Recombinant Bovine FGF2 Protein E.coli N/A
Bovine FGF2-4422B Recombinant Bovine FGF2 protein, His-tagged Yeast N-His 10-155aa
Bovine FGF2-399F Active Recombinant Bovine FGF2 Protein (146 aa) E.coli 146
Bovine/Porcine FGF2-06B Recombinant Bovine/Porcine FGF2 Protein E.coli 145 aa
Bovine/Porcine FGF2-07B Recombinant Bovine/Porcine FGF2 Protein E.coli 154 aa
Cattle FGF2-2185C Recombinant Cattle FGF2 Protein, His-tagged E.coli N-His Pro10-Ser155
Cattle FGF2-2186C Recombinant Cattle FGF2 Protein, His-tagged E.coli N-His Phe26-Ser155 (Accession # P03969)
Porcine FGF2-01P Active GMP Recombinant Porcine FGF2 Protein, His-Tagged E.coli His
Zebrafish FGF2-12089Z Recombinant Zebrafish FGF2 Mammalian Cell His
Zebrafish fgf2-08Z Recombinant Zebrafish fgf2 Protein E.coli
Pig FGF2-78P Recombinant Active Pig FGF2 Protein, His-tagged(N-ter) E.coli His(N-ter)
Pig FGF2-929P Recombinant Pig FGF2 Protein, His-tagged E.coli N-His Pro10-Ser154
Chicken FGF2-6983C Recombinant Chicken FGF2 Mammalian Cell His
Chicken FGF2-6739C Recombinant Chicken FGF2 protein, His-tagged E.coli His Phe29~Gly143
Chicken FGF2-7575C Recombinant Chicken FGF2 protein, His&Myc-tagged E.coli N-His&C-Myc 13-158aa
bFGF-10A Recombinant bFGF agarose fast flow N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource
  • FGF2 Related Signal Pathway

FGF2 involved in several pathways and played different roles in them. We selected most pathways FGF2 participated on our site, such as MAPK signaling pathway, Ras signaling pathway, Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with FGF2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
MAPK signaling pathwayAKT3A;CACNA1H;MAPK8A;MECOM;TGFBR1;MAP3K3;MAPKAPK3;CACNA2D4;AKT1
Ras signaling pathwayFGF13;GNG10;PIK3R1;PTPN11;GRIN2A;GAB1;Kitl;KSR1;MAPK10
Rap signaling pathwayMAPK13;APBB1IP;TLN1;PIK3R5;FGF4;SKAP1;ITGB2L;RAP1B;BRAF
PIK-Akt signaling pathwayPRKCA;INS;IL4R;Fasl;TSC2;LAMB2;LAMA3;PPP2R2C;LAMB3
Signaling pathways regulating pluripotency of stem cellsFGFR4;FZD1;MAP2K2;PCGF6;PIK3CD;POU5F1;WNT7A;WNT3;KLF4
Regulation of actin cytoskeletonGNA12A;HRAS;PPP1CB;ARHGEF4;SOS1;RAC3A;ITGA8;ACTN4;Pdgfa&Pdgfb
Pathways in cancerGNG12;PRKACG;PIAS2;ITGA6;FGF7;WNT9A;F2R;WNT9B;PLCG1
Proteoglycans in cancerPIK3R2;WNT7B;FN1;IGF1R;PDPK1;HPSE2;FZD5;WNT3;WNT3A
MelanomaMITF;CCND1;PDGFD;PIK3R1;AKT1;KRAS;PDGFRA;HGF;PDGFB

FGF2 has several biochemical functions, for example, chemoattractant activity, cytokine activity, fibroblast growth factor receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FGF2 itself. We selected most functions FGF2 had, and list some proteins which have the same functions with FGF2. You can find most of the proteins on our site.

Function Related Protein
chemoattractant activityFGF10;PDGFB;SAA2;FGF8;CXCL12A;CXCL12B;MIF;VEGFA;SAA4
cytokine activityGDF15;NODAL;IFNA2;GM13289;TNFSF14;OSM;CD70;C1QTNF4;GDF2
fibroblast growth factor receptor bindingFGF20;FRS2;FGF6A;FGF10A;FGF1A;FGF6B;FGF22;FGF4;FGF21
growth factor activityFGF12B;PDGFAB;GPI;IL11;MIA1;FGF11A;BMP7B;GDF3;PDGFAA
heparin bindingNRP2;FGF1;Itgam&Itgb2;PCOLCE2;AAMP;PCOLCE;ANG;COMP;ZNF146
ligand-dependent nuclear receptor transcription coactivator activityPRKCB;PUS1;USP22;CCAR1;THRAP3;KDM1A;SLC30A9;WDR77;CALCOCO1
protein bindingTOM1L1;PAK3;GRHL3;PUS7L;GIPC1;OLIG1;SELE;IL4R;RNF149

FGF2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FGF2 here. Most of them are supplied by our site. Hope this information will be useful for your research of FGF2.

FGFR1; FGFR2; FGFBP1; chondroitin sulfate; ssr; DCN; FGFR1; FGFR2; q6dtl8_bovin; ANOS1

Research Area

Related articles

Correa, D; Somoza, RA; et al. Sequential exposure to fibroblast growth factors (FGF) 2, 9 and 18 enhances hMSC chondrogenic differentiation. OSTEOARTHRITIS AND CARTILAGE 23:443-453(2015).
Bohnsack, RN; Warejcka, DJ; et al. Expression of Insulin-Like Growth Factor 2 Receptor in Corneal Keratocytes During Differentiation and in Response to Wound Healing. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 55:7697-7708(2014).
  • Q&As
  • Reviews

Q&As (6)

Ask a question
What is the biological function of FGF2? 11/10/2022

FGF2 promotes cell migration and angiogenesis and regulates bone homeostatic balance.

Where is FGF2 mainly expressed? 10/22/2022

FGF2 is widely expressed in the nervous system.

In which tissues of sheep is FGF2 primarily expressed? 01/01/2022

FGF2 is mainly expressed in tissues such as mammary glands and ovaries of sheep.

What protein does FGF2 share high homology with? 03/08/2021

FGF1 has a high degree of homology with FGF2.

What diseases is FGF2 involved in? 02/12/2021

FGF2 is involved in diseases such as cardiovascular disease, breast disease and bone homeostasis.

How does FGF2 regulate bone homeostasis? 11/21/2020

FGF2 negatively regulates bone homeostasis.

Customer Reviews (2)

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Reviews
07/14/2022

    The technical expert communicated with me in time to understand the progress of my experiment and gave me suggestions for improvement.

    02/04/2022

      The purchased protein is suitable for WB experiments and I am satisfied with the results.

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