|Official Full Name||Fibroblast Growth Factor 2 (basic)|
|Background||roblast growth factors, or FGFs, are a family of growth factors involved in angiogenesis, wound healing, and embryonic development. The FGFs are heparin-binding proteins and interactions with cell-surface associated heparan sulfate proteoglycans have been shown to be essential for FGF signal transduction. FGFs are key players in the processes of proliferation and differentiation of wide variety of cells and tissues.|
|Synonyms||FGF2; fibroblast growth factor 2 (basic); BFGF; FGFB; HBGF-2; heparin-binding growth factor 2; prostatropin; OTTHUMP00000037513; basic fibroblast growth factor bFGF; Fgf-2|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
FGF2 involved in several pathways and played different roles in them. We selected most pathways FGF2 participated on our site, such as MAPK signaling pathway, Ras signaling pathway, Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with FGF2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|MAPK signaling pathway||NLK; JIP1; TGFBR1A; TAOK1; MAPK8; DUSP16; MAX; ATF4B1; PRKACG; PPP5C|
|Ras signaling pathway||ZAP70; GNB4; PLA2G4F; PLD1; GRIN2A; EFNA4; MLLT4; VEGFC; REL; PIK3CD|
|Rap signaling pathway||RAC1; PRKD3; GNAI2; FGF17; ANGPT2; FGF9; PIK3R3; INS2; PIK3CA; Pdgfa&Pdgfb|
|PIK-Akt signaling pathway||Fasl; HSP90AA1; KLK1B4; TCL1B4; LAMA5; ANGPT2; FGF5; CCNE2; GNB1; ITGA2B|
|Signaling pathways regulating pluripotency of stem cells||PIK3CG; LEFTY2; SETDB1; WNT7B; ACVR1; ZIC3; ESRRB; WNT3A; ID3; BMI1|
|Regulation of actin cytoskeleton||PIK3R1; FGF14; FGF7; RHOAB; FGF3; ITGB7; ARAF; MYLK; RAC1; ABI2|
|Pathways in cancer||PTGER2; WNT9B; FGF11; GRB2; RASSF1; LAMA5; AGTR1A; FGF17; NFKB1; PTGER1|
|Proteoglycans in cancer||BRAF; MAPK12; FZD1; ACTG1; GPC3; PLCG2; MMP2; WNT1; RPS6KB2; WNT4|
|Melanoma||FGF19; AKT1; FGF3; BRAF; MITF; PDGFRB; FGF2; PDGFB; Fgf15; PIK3CG|
FGF2 has several biochemical functions, for example, chemoattractant activity, cytokine activity, fibroblast growth factor receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FGF2 itself. We selected most functions FGF2 had, and list some proteins which have the same functions with FGF2. You can find most of the proteins on our site.
|chemoattractant activity||VEGFC; CCL16; HMGB2; SAA2; FGF10; HMGB1; SCG2; VEGFA; CCL15; SAA3|
|cytokine activity||IFNPHI2; IL6; IL34; IFNG; TGFB1; CSF3; GPI1; IL33; IL22; IL16|
|fibroblast growth factor receptor binding||FGF6; FGF1; FGF20; FGF16; FRS3; FGF1A; KLB; FGF8B; FGF2; FGF3|
|growth factor activity||IL9; IGF2; KLK1B3; PDGFA; FGF9; INHBAB; TDGF1; CTGF; VEGFAB; INHBB|
|heparin binding||OGN; PLA2G2D; CYR61L1; CCL5; THBS4; VEGFB; PF4V1; CXCL13; HRG; CTSG|
|ligand-dependent nuclear receptor transcription coactivator activity||WDR77; FGF2; LRP2BP; SLC30A9; PPRC1; ENY2; AASS; CCAR1; ZMIZ2; HMGA1|
|protein binding||HIST1H1C; MED25; VASNA; PABPC1; CD93; LRP1; SENP5; BMP7; USH1C; TMEM106B|
FGF2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FGF2 here. Most of them are supplied by our site. Hope this information will be useful for your research of FGF2.
FGFR1; FGFR2; FGFBP1; chondroitin sulfate; ssr; DCN; FGFR1; FGFR2; q6dtl8_bovin; ANOS1
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