fgf2
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  • Official Full Name
  • Fibroblast Growth Factor 2 (basic)
  • Background
  • roblast growth factors, or FGFs, are a family of growth factors involved in angiogenesis, wound healing, and embryonic development. The FGFs are heparin-binding proteins and interactions with cell-surface associated heparan sulfate proteoglycans have been shown to be essential for FGF signal transduction. FGFs are key players in the processes of proliferation and differentiation of wide variety of cells and tissues.
  • Synonyms
  • FGF2; fibroblast growth factor 2 (basic); BFGF; FGFB; HBGF-2; heparin-binding growth factor 2; prostatropin; OTTHUMP00000037513; basic fibroblast growth factor bFGF; Fgf-2
Cat.#:FGF2-022HTag:
Source (Host):E.coliSpecies:Human
Product nameRecombinant Human FGF2 Protein
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Cat.#:FGF2-13HTag:
Source (Host):E.coliSpecies:Human
Product nameRecombinant Human FGF2 Protein, non-tagged, Biotinylated
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Cat.#:FGF2-40BTag:
Source (Host):Bovine brainSpecies:Bovine
Product nameNative Bovine FGF2 Protein
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Cat.#:FGF2-12BTag:
Source (Host):E. coliSpecies:Bovine
Product nameRecombinant Bovine FGF2 Protein
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Cat.#:FGF2-1968MTag:
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse FGF2 Protein
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Cat.#:FGF2-1967RTag:
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat FGF2 Protein
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Cat.#:FGF2-4381BTag:
Source (Host):YeastSpecies:Bovine
Product nameRecombinant Bovine FGF2 Protein
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Cat.#:FGF2-4387RTag:
Source (Host):YeastSpecies:Rabbit
Product nameRecombinant Rabbit FGF2 Protein
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Cat.#:FGF2-567HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Fibroblast Growth Factor 2 (basic)
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Cat.#:FGF2-11HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Fibroblast Growth Factor-basic
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Cat.#:FGF2-12HTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human FGF2
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Cat.#:FGF2-169HTag:N/A
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human FGF2
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Cat.#:FGF2-198HTag:His/S
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human FGF2 protein, His/S-tagged
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Cat.#:FGF2-19HTag:ERHV-His
Source (Host):Barley grainSpecies:Human
Product nameRecombinant Human FGF2 protein, ERHV-His-tagged
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Cat.#:FGF2-1HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human FGF basic protein
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Cat.#:FGF2-22HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human FGF2 protein, GST-tagged
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Cat.#:FGF2-27258THTag:His
Source (Host):Species:Human
Product nameRecombinant Human FGF2, His-tagged
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Cat.#:FGF2-27596THTag:
Source (Host):Species:Human
Product nameRecombinant Human FGF2
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Cat.#:FGF2-2784HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human FGF2 protein, His-tagged
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Cat.#:FGF2-293HTag:Strep II
Source (Host):HEK293Species:Human
Product nameRecombinant Human FGF2, StrepII-tagged
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Cat.#:FGF2-41HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human FGF2 protein, MYC/DDK-tagged
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Cat.#:FGF2-482HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human FGF2, None tagged
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Cat.#:FGF2-5HTag:N/A
Source (Host):YeastSpecies:Human
Product nameRecombinant Human Basic Fibroblast Growth Factor
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Cat.#:FGF2-730HTag:Ala
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human FGF2, Ala-tagged
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Cat.#:FGF2-8499HTag:His
Source (Host):Sf 21 Insect cellsSpecies:Human
Product nameRecombinant Human FGF2, His-tagged
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Cat.#:FGF2-8856HTag:
Source (Host):Hordeum vulgareSpecies:Human
Product nameRecombinant Human Fibroblast Growth Factor 2 (basic)
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Cat.#:FGF2-91HTag:HIS
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human FGF2,His-tagged
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Cat.#:Fgf2-12MTag:N/A
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Fibroblast Growth Factor-basic
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Cat.#:Fgf2-199MTag:His/S
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Fgf2 protein, His/S-tagged
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Cat.#:FGF2-5847MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse FGF2 Protein
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Cat.#:Fgf2-829MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Fgf2 Protein, His-tagged
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Cat.#:Fgf2-200RTag:His/S
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Fgf2 protein, His/S-tagged
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Cat.#:FGF2-2331RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat FGF2 Protein
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Cat.#:Fgf2-40RTag:N/A
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Fibroblast Growth Factor(basic)
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Cat.#:FGF2-2785RTag:His
Source (Host):E. coliSpecies:Rabbit
Product nameRecombinant Rabbit FGF2 protein, His-tagged
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Cat.#:FGF2-6983CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken FGF2
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Cat.#:FGF2-12089ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish FGF2
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Cat.#:FGF2-018ETag:N/A
Source (Host):E. coliSpecies:Bovine
Product nameRecombinant Bovine FGF2 (10-155aa), Ala tagged
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Cat.#:FGF2-678HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Fibroblast Growth Factor 2 (basic) (aa 146)
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Cat.#:Fgf2-664MTag:N/A
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Fibroblast Growth Factor 2
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Cat.#:Fgf2-680MTag:N/A
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Fibroblast Growth Factor 2
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Cat.#:FGF2-650BTag:N/A
Source (Host):E. coliSpecies:Bovine
Product nameRecombinant Bovine Fibroblast Growth Factor 2
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Cat.#:FGF2-1182BTag:N/A
Source (Host):E. coliSpecies:Bovine
Product nameRecombinant Bovine Fibroblast Growth Factor 2 (basic)
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Cat.#:FGF2-014OTag:N/A
Source (Host):RiceSpecies:Human
Product nameRecombinant Human FGF2
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Cat.#:FGF2-022ETag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human FGF2 (143-288aa), Ala tagged
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Cat.#:FGF2-26551THTag:
Source (Host):E. coliSpecies:Human
Product nameNative Human FGF2
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Cat.#:FGF2-34BTag:
Source (Host):Species:Bovine
Product nameNative Bovine bFGF
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Cat.#:FGF2-638HCLTag:
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human FGF2 cell lysate
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Cat.#:bFGF-10ATag:
Source (Host):Species:
Product nameRecombinant bFGF agarose fast flow
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Cat.#:FGF2-108HGTag:
Source (Host):E. coliSpecies:Human
Product nameGMP Recombinant Human FGF2 Protein
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Cat.#:FGF2-4345HGTag:
Source (Host):E. coliSpecies:Human
Product nameGMP Recombinant Human FGF2 protein
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Cat.#:FGF2-105HTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Basic Fibroblast Growth Factor (rDNA derived) Reference standard
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Involved Pathway

FGF2 involved in several pathways and played different roles in them. We selected most pathways FGF2 participated on our site, such as MAPK signaling pathway, Ras signaling pathway, Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with FGF2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
MAPK signaling pathway
TNFRSF1A; STMN1; PDGFRB; MAP3K5; PRKACBB; CACNG2A; PLA2G4F; NFATC1; MAPK8A; RASA2
Ras signaling pathway
FLT4; RELA; CALM1; PLA2G4C; LOC608458; RASGRP3; NF1; MAPK1; GNB3; FLT1
Rap signaling pathway
FGF12; IGF1; KRIT1; SRC; FGF19; LCP2; MAP2K6; ITGB3; RAPGEF5; PIK3CG
PIK-Akt signaling pathway
CREB3L1; GH2; LAMA5; EIF4E1B; IKBKB; RELA; GNB3; SGK1; TEK; PPP2R5A
Signaling pathways regulating pluripotency of stem cells
NEUROG1; FZD5; WNT16; ONECUT1; ID1; DLX5; SMAD2; Fzd4; PCGF6; PIK3CG
Regulation of actin cytoskeleton
WASL; FGF22; VAV3B; PIP5KL1; PFN2L; WAS; FGF16; BRAF; FGF19; ACTB2
Pathways in cancer
STK4; GNGT1; HIF1A; CCDC6; LAMA5; MAPK9; IL-8; DAPK1; DAPK2; PLCG1
Proteoglycans in cancer
PAK1; PIK3CA; AKT1; ITGA5; PTPN6; HIF1A; CAMK2B; ROCK2; RPS6; MMP9
Melanoma
ARAF; PIK3R5; MAPK1; FGF12; FGF21; FGF8; FGF10; PTEN; PDGFRB; Fgf15

Protein Function

FGF2 has several biochemical functions, for example, chemoattractant activity, cytokine activity, fibroblast growth factor receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FGF2 itself. We selected most functions FGF2 had, and list some proteins which have the same functions with FGF2. You can find most of the proteins on our site.
Function
Related Protein
Function chemoattractant activity
Related Protein SAA3; CCL15; CCL3; CXCL12; FIGF; VEGFA; SAA1; VHL; SAA2; BMP4
Function cytokine activity
Related Protein TNF; CCL38A.5; TGFB2; BMP1; FGF2; CCL38A.4; SECTM1; IFNPHI1; CLCF1; WNT5A
Function fibroblast growth factor receptor binding
Related Protein FGF3; FGF5; FGF20B; FGF20; FRS2; FGF4; FGF16; FGF6; FGF10B; KLB
Function growth factor activity
Related Protein EREG; HDGF; IGF3; THBS4B; FGF13A; AMH; FGF14; PDGFA; TGFB2; EGF
Function heparin binding
Related Protein ADAMTS3; RSPO3; FGFBP3; FBLN7; SLIT1A; KAL1; PCOLCE2; FGF9; WISP1A; CHRD
Function ligand-dependent nuclear receptor transcription coactivator activity
Related Protein SMARCD3; FGF2; SLC30A9; KDM1A; PUS1; ZCCHC12; ENY2; USP22; LRP2BP; NCOA3
Function protein binding
Related Protein ZCCHC11; TIMP3; KISS1; ORC2L; IRF7; LINGO1B; TOPORS; PLD2; ZNF16; FOXP2

Interacting Protein

FGF2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FGF2 here. Most of them are supplied by our site. Hope this information will be useful for your research of FGF2.
FGFR1; FGFR2; FGFBP1; chondroitin sulfate; ssr; DCN; FGFR1; FGFR2; q6dtl8_bovin; ANOS1

FGF2 Related Articles

Correa, D; Somoza, RA; et al. Sequential exposure to fibroblast growth factors (FGF) 2, 9 and 18 enhances hMSC chondrogenic differentiation. OSTEOARTHRITIS AND CARTILAGE 23:443-453(2015).
Bohnsack, RN; Warejcka, DJ; et al. Expression of Insulin-Like Growth Factor 2 Receptor in Corneal Keratocytes During Differentiation and in Response to Wound Healing. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 55:7697-7708(2014).