IL11 Protein


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Official Full Name interleukin 11
Background The protein encoded by this gene is a member of the gp130 family of cytokines. These cytokines drive the assembly of multisubunit receptor complexes, all of which contain at least one molecule of the transmembrane signaling receptor IL6ST (gp130). This cytokine is shown to stimulate the T-cell-dependent development of immunoglobulin-producing B cells. It is also found to support the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2012]
Synonyms IL11; interleukin 11; AGIF; IL-11; interleukin-11; oprelvekin; adipogenesis inhibitory factor;
    • Species :
    • Cynomogus
    • Cynomolgus monkey
    • Human
    • Mouse
    • Rat
    • Source :
    • E. coli
    • E.coli
    • HEK293
    • HEK293F
    • Human
    • Human Cells
    • Insect Cell
    • Mouse
    • P.pastoris
    • Sf21 Insect Cell
    • Yeast
    • Tag :
    • Fc
    • His
    • His&Myc
    • His(N-ter)
    • T7
    • MBP&His-Avi
    • Met
    • N/A
    • N-His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human IL11-325H Recombinant Human IL11 Human N/A
    Human IL11-416H Recombinant Human Interleukin-11 Human N/A
    Human IL11-953H Recombinant Human IL11 Protein P.pastoris N/A
    Mouse Il11-01M Recombinant Mouse Il11 Protein, His-Tagged E.coli His
    Human IL11-123H Recombinant Human IL11 protein E.coli N/A
    Human IL11-19H Recombinant Human Interleukin-11 Yeast N/A
    Human IL11-218H Recombinant Human Interleukin 11 Sf21 Insect Cell N/A
    Human IL11-29630TH Recombinant Human IL11 E.coli N/A
    Human IL11-464H Recombinant Human IL11, None tagged E.coli Fc
    Human IL11-503H Recombinant Human IL11 protein, His-tagged HEK293F His
    Human IL11-551H Recombinant Human Interleukin 11 Human N/A
    Human IL11-842H Recombinant Human IL11 protein, His & T7-tagged E.coli His/T7
    Mouse Il11-161M Recombinant Mouse Il11 protein E.coli N/A
    Mouse Il11-586M Recombinant Mouse interleukin 11 Mouse N/A
    Mouse Il11-842M Recombinant Mouse Il11 Protein E.coli N/A
    Mouse Il11-843M Recombinant Mouse Il11 protein, His-tagged E.coli His
    Human IL11-5249HCL Recombinant Human IL11 293 Cell Lysate HEK293 N/A
    Human IL11-061H Recombinant Human IL11 Protein E. coli
    Mouse Il11-1373M Recombinant Mouse Il11 protein, MBP&His-Avi-tagged, Biotinylated E.coli MBP&His-Avi
    Cynomolgus monkey Il11-1374C Recombinant Cynomolgus monkey Il11 protein, MBP&His-Avi-tagged, Biotinylated E.coli MBP&His-Avi
    Rat Il11-1375R Recombinant Rat Il11 protein, MBP&His-Avi-tagged, Biotinylated E.coli MBP&His-Avi
    Human IL11-137H Recombinant Active Human IL11 Protein, His-tagged(N-ter) E.coli His(N-ter)
    Mouse Il11-138M Recombinant Active Mouse IL11 Protein, His-tagged(N-ter) E.coli His(N-ter)
    Human IL11-151H Recombinant Human IL11 Protein, His-tagged Human Cells His
    Rat Il11-1659R Recombinant Rat Il11 Protein, His-tagged E.coli N-His
    Human IL11-2289H Recombinant Human IL11 Protein, His-tagged E.coli N-His
    Rat Il11-4756R Recombinant Rat Il11 protein, His&Myc-tagged E.coli His&Myc
    Human IL11-101HG GMP Recombinant Human IL11 Protein Insect Cell N/A
    Human IL11-121HG GMP Recombinant Human IL11 protein, His-tagged HEK293 His
    Human IL11-124H Human Interleukin-11 (rDNA derived) Reference standard N/A
    Human IL11-2016H Recombinant Human IL11 Protein, Met-tagged E.coli Met
    Human IL11-4326HG GMP Recombinant Human IL11 protein E.coli N/A
    Human IL11-P012H Recombinant Human IL11 therapeutic protein E.coli N/A
    Mouse Il11-085M Recombinant Mouse Il11 Protein E.coli
    Cynomogus IL11-938C Recombinant Cynomogus IL11 Protein E. coli
    Cynomogus IL11-939C Recombinant Cynomogus IL11 Protein, His-tagged E. coli His

    IL11 involved in several pathways and played different roles in them. We selected most pathways IL11 participated on our site, such as Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Integrated Pancreatic Cancer Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with IL11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine-cytokine receptor interaction IL4; IL22; CCL2; TNFSF13; KITLGB; TNFRSF19; CD27; IL23; TNFSF4; CCR6A
    Hematopoietic cell lineage CSF3R; CD1E; CD59A; CR1; CD24; CSF1R; CD38; Flt3l; IL7; CD1D
    Integrated Pancreatic Cancer Pathway RB1CC1; GPRC5A; TOP1; FKBP1B; TFF1; TOP2A; JUND; NOXA1; AGA; RAPGEF3
    Interleukin-11 Signaling Pathway BGLAP; IL11
    Jak-STAT signaling pathway IFNA21; IFNW1; STAT5B; IL2RGB; SOS1; SOCS3; IFNA1; BCL2A; Il6ra; CRLF2
    Rheumatoid arthritis Il23a; Il12b; Il23a; HLA-DOA; CXCL5; TEK; HLA-DRA; ATP6V1D; CTLA4; CCL3L3; IL1A

    IL11 has several biochemical functions, for example, cytokine activity, growth factor activity, interleukin-11 receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IL11 itself. We selected most functions IL11 had, and list some proteins which have the same functions with IL11. You can find most of the proteins on our site.

    Function Related Protein
    cytokine activity WNT5A; IFNK; BMP4; FLT3LG; IL37; GDF10B; BMP2; IL5; IL20; CD40LG
    growth factor activity BMP8A; KITLG; FGF13B; IL5; GDF6; IGF2; FGF9; CXCL1; GDF6B; RABEP1
    interleukin-11 receptor binding IL11
    protein binding CKMT1; CCDC59; JAG1; COL6A2; HLA-DRB3; ZBTB7A; MTERFD2; COBRA1; SAC3D1; MASP1

    IL11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL11 here. Most of them are supplied by our site. Hope this information will be useful for your research of IL11.

    MAGEA11; MAGEA11

    Mannam, VKR; Lewis, RE; et al. The fate of renal allografts hinges on responses of the microvascular endothelium. EXPERIMENTAL AND MOLECULAR PATHOLOGY 94:398-411(2013).
    Dams-Kozlowska, H; Gryska, K; et al. A designer hyper interleukin 11 (H11) is a biologically active cytokine. BMC BIOTECHNOLOGY 12:-(2012).


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