Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at IMMUNOLOGY2024™|May 3-7, 2024|Booth #512

F3

  • Official Full Name

    coagulation factor III (thromboplastin, tissue factor)

  • Overview

    This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
  • Synonyms

    F3; coagulation factor III (thromboplastin, tissue factor); TF; TFA; CD142; tissue factor;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Transfected Stable Cell Lines
  • Protein Pre-coupled Magnetic Beads
  • Antibody
  • Bos taurus (Bovine)
  • Cattle
  • Cynomolgus
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Oryctolagus cuniculus (Rabbit)
  • Rabbit
  • Rat
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293T
  • Human Cell
  • Human Cells
  • In Vitro Cell Free System
  • Insect Cell
  • Mammalian cells
  • Rabbit
  • T7 cell
  • Wheat Germ
  • Yeast
  • C
  • His
  • Fc
  • Flag
  • GST
  • His (Fc)
  • Avi
  • His|S
  • His|T7
  • SUMO
  • Myc
  • DDK
  • MYC
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human F3-22H Active Recombinant Human F3 protein Insect Cell N/A 263 amino acids
Human F3-20H Active Recombinant Human F3 protein, His-tagged Mammalian cells His
Human F3-28H Recombinant Human Soluble Tissue Factor E.coli N/A
Human F3-6924H Active Recombinant Human F3 protein, Fc-tagged HEK293 Fc Ser 33 - Glu 251
Human F3-18H Recombinant Human Tissue Factor, Non-Lipidated N/A
Human F3-99H Recombinant Human F3, His-tagged E.coli His
Human F3-3619H Recombinant Human F3 Protein Wheat Germ N/A
Human F3-6925H Recombinant Human F3 protein(Met1-Glu251), His-tagged HEK293 C-His Met1-Glu251
Human F3-3620H Recombinant Human F3 Protein, GST-tagged Wheat Germ GST
Human F3-19H Recombinant Human Tissue Factor, Lipidated N/A
Human F3-463H Recombinant Human Coagulation Factor III (Thromboplastin, Tissue Factor) Insect Cell N/A
Human F3-1691HCL Recombinant Human F3 cell lysate Human Cell N/A
Human F3-2046H Recombinant Human F3 Protein, His-tagged HEK293 His Gly34-Glu251
Human F3-172H Recombinant Human Thromboplastin, Plain Reference standard N/A
Human F3-883H Recombinant Human F3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human F3-958H Recombinant Human F3 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human F3-565H Recombinant Human F3 Protein (Met1-Ser295), His-tagged Insect Cell His Met1-Ser295
Human F3-847H Recombinant Human F3 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human F3-2878H Recombinant Human F3 protein, His-SUMO-tagged E.coli His-SUMO 33-251aa
Human F3-151H Recombinant Human F3 Protein, His-tagged Human Cells His
Human F3-2109HFL Recombinant Full Length Human F3 Protein, C-Flag-tagged Mammalian cells Flag
Human F3-4499HF Recombinant Full Length Human F3 Protein In Vitro Cell Free System 144 amino acids
Human F3-883H-B Recombinant Human F3 Protein Pre-coupled Magnetic Beads HEK293
Human F3-029H Recombinant Human F3 Protein, C-His-tagged E.coli C-His
Human F3-1474H Recombinant Human F3 Protein (Met1-Glu251), N-His tagged E.coli N-His Met1-Glu251
Human F3-2056H Recombinant Human F3 Protein (Gly34-Glu251), C-His tagged Mammalian cells C-His Gly34-Glu251
Human F3-2643H Active Recombinant Human F3 protein, His-tagged HEK293 His Gly34-Glu251
Human F3-4096H Recombinant Human F3 Protein (Met1-Glu251), C-His tagged Mammalian cells C-His Met1-Glu251
Mouse F3-32M Active Recombinant Mouse F3 protein, His-tagged Mammalian cells His
Mouse F3-459M Active Recombinant Mouse Coagulation Factor III E.coli N/A
Mouse F3-426M Active Recombinant Mouse F3 protein, His-tagged HEK293 His Met1-Glu251
Mouse F3-47M Recombinant Mouse F3 Protein, His-tagged Insect Cell His
Mouse F3-2734M Recombinant Mouse F3 protein, His-tagged E.coli His Gly30~Glu251 (Accession # P20352)
Mouse F3-2503MCL Recombinant Mouse F3 cell lysate Human Cell N/A
Mouse CAB11537RM Rabbit Anti-Mouse Coagulation Factor III / Tissue Factor / CD142 Monoclonal Antibody Rabbit N/A
Mouse F3-7203M Recombinant Mouse F3 Protein, His-tagged His 29-251
Mouse F3-2921M Recombinant Mouse F3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse F3-2921M-B Recombinant Mouse F3 Protein Pre-coupled Magnetic Beads HEK293
Mouse F3-999M Recombinant Mouse F3 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Rat F3-8752R Recombinant Rat F3, His tagged Human Cell His
Rat F3-29R Recombinant Rat F3, His-tagged Human Cell His
Rat F3-2735R Recombinant Rat F3 protein, His-tagged E.coli His Gly30~Glu252
Rat F3-1256RCL Recombinant Rat F3 cell lysate Human Cell N/A
Rabbit F3-1029R Recombinant Rabbit F3 Protein, His-tagged HEK293 His
Rabbit F3-455R Recombinant Rabbit Coagulation Factor III (Thromboplastin, Tissue Factor) T7 cell N/A
Rabbit F3-2736R Recombinant Rabbit F3 protein, His & S-tagged E.coli His/S Ala33~Ala292 (Accession # P24055)
Rabbit F3-368R Recombinant Rabbit F3 Protein, His-tagged Yeast His Ala33-Met250
Rabbit F3-15R Rabbit Thromboplastin Reference Standard N/A
Bos taurus (Bovine) RFL7914BF Recombinant Full Length Bovine Tissue Factor(F3) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (36-292)
Cattle F3-2733C Recombinant Cattle F3 protein, His & T7-tagged E.coli His/T7 Thr36~Ala292 (Accession # P30931)
Cynomolgus F3-1023C Recombinant Cynomolgus F3 Protein (Met1-Glu252), His-tagged HEK293 His Met1-Glu252
Homo sapiens (Human) RFL14895HF Recombinant Full Length Human Tissue Factor(F3) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (33-295)
Mus musculus (Mouse) RFL521MF Recombinant Full Length Mouse Tissue Factor(F3) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (29-294)
Oryctolagus cuniculus (Rabbit) RFL1640OF Recombinant Full Length Rabbit Tissue Factor(F3) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (33-292)
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

F3 involved in several pathways and played different roles in them. We selected most pathways F3 participated on our site, such as Complement and coagulation cascades, which may be useful for your reference. Also, other proteins which involved in the same pathway with F3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Complement and coagulation cascadesC4BPA;CD46;C1QA;MBL1;FGG;PROC;FGB;C3AR1;SERPINA1D

F3 has several biochemical functions, for example, cytokine receptor activity, phospholipid binding, protease binding. Some of the functions are cooperated with other proteins, some of the functions could acted by F3 itself. We selected most functions F3 had, and list some proteins which have the same functions with F3. You can find most of the proteins on our site.

Function Related Protein
cytokine receptor activityIL31RA;IL1RL1;IL13RA2;CRFB12;IL20RA;IL2RGB;CRFB17;IL21R.2;IRX1
phospholipid bindingPSD4;SEC14L2;NBEA;VAMP2;PON1;PICALMA;APOB;PLA2G4C;NUP35
protease bindingSERPINA1;INSL3;CNTNAP2;ADRM1;FLOT2;CFLAR;INS1;MBP;RYR1
protein bindingADAMTSL5;HPGDS;PSMD7;TXNRD3;FKBP3;DNAJC28;TRPV6;IL1RL1;LIPT2

F3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with F3 here. Most of them are supplied by our site. Hope this information will be useful for your research of F3.

F7

Gene Family

TGF Cytokines

Research Area

Related articles

Bet, A; Maze, EA; et al. The HIV-1 Antisense Protein (ASP) induces CD8 T cell responses during chronic infection. RETROVIROLOGY 12:-(2015).
Sritharan, N; Choudhury, M; et al. Highly immunoreactive antibodies against the rHup-F2 fragment (aa 63-161) of the iron-regulated HupB protein of Mycobacterium tuberculosis and its potential for the serodiagnosis of extrapulmonary and recurrent tuberculosis. EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES 34:33-40(2015).
  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All F3 Products

Required fields are marked with *

My Review for All F3 Products

Required fields are marked with *

logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends