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  • Official Full Name


  • Overview

    Thyroid-stimulating hormone (also known as thyrotropin, TSH, or hTSH for human TSH) is a hormone that stimulates the thyroid gland to produce thyroxine (T4), and then triiodothyronine (T3) which stimulates the metabolism of almost every tissue in the body. It is a glycoprotein hormone synthesized and secreted by thyrotrope cells in the anterior pituitary gland, which regulates the endocrine function of the thyroid gland.
  • Synonyms

    TSH; thyrotropin; TSH; hTSH; human TSH; Thyroid-stimulating hormone;

  • Native Proteins
  • Recombinant Proteins
  • Transfected Stable Cell Lines
  • Therapeutic Proteins
  • Bovine
  • Human
  • Bovine
  • Bovine Pituitary Gland
  • CHO
  • E.coli
  • Human Pituitary Gland
  • Yeast
  • His
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human TSH-108H Active Native Human Thyroid Stimulating Hormone Human Pituitary Gland N/A
Human TSH-25H Active Native Human Thyroid Stimulating Hormone protein Human Pituitary Gland N/A
Human TSH-42H Recombinant Human Thyroid Stimulating Hormone Yeast N/A
Human TSH-192H Human Thyroid Stimulating Hormone Reference standard N/A
Human TSH-40H Recombinant Human TSH protein E.coli N/A
Human TSH-16H Recombinant Human Thyroid Stimulating Hormone Reference standard CHO N/A
Human TSH-198H Recombinant Human Thyroid Stimulating Hormone Reference standard N/A
Human TSH-P036H Recombinant Human TSH therapeutic protein N/A
Human TSH-01H Recombinant Human Thyroid Stimulating Hormone(TSH) Protein, His-tagged CHO His
Bovine TSH-1315B Active Native Bovine TSH Protein Bovine Pituitary Gland N/A
Bovine TSH-1312B Active Native Bovine TSH Protein Bovine N/A
Bovine TSH-10B Active Native Bovine TSH Protein Bovine Pituitary Gland N/A

TSH involved in several pathways and played different roles in them. We selected most pathways TSH participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TSH were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

TSH has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by TSH itself. We selected most functions TSH had, and list some proteins which have the same functions with TSH. You can find most of the proteins on our site.

Function Related Protein

TSH has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TSH here. Most of them are supplied by our site. Hope this information will be useful for your research of TSH.

  • Q&As
  • Reviews

Q&As (16)

Ask a question
What the TSHR signal transduction, regulation, and maturation? 04/14/2023

The TSHR, long known to signal via cAMP, can induce both the phospholipase C (PLC) and the protein kinase A signal transduction systems. Intracellular Ca2+ and PLC regulate iodide efflux, H2O2 production, and thyroglobulin iodination, while adenylate cyclase and cAMP regulate iodide uptake and transcription of thyroglobulin (Tg), thyroid peroxidase (TPO), and the sodium-iodide symporter.

Why the puzzling size diversity of TSHRs detected by western blotting? 04/14/2023

Presumably by protein disulfide isomerase leading to release of the α subunit from the membrane-bound receptor.

What is associated with a high TSH value? 04/14/2023

High-normal TSH-values are associated with an adverse lipid profile, high blood pressure, high body mass index (BMI), metabolic syndrome and fatal coronary heart disease.

How is TSH level regulated in brain? 04/14/2023

It is known that the majority of the metabolically active T3 in the brain is not derived from the circulation, but produced locally by the effect of D2 on T4. Locally produced T3 largely acts on the hypothalamus and pituitary glands to control TSH levels.

Are TSH receptors expressed in places other than the thyroid gland? 04/14/2023

Thyroid stimulating hormone receptors have been identified in mammalian heart, bone, kidneys, brain, skin, adipose, hair follicles, thymus, lymphocytes, astrocyte cultures and in fish testes.

How can thyroid cancer be treated by inhibiting thyrotropin? 04/14/2023

Levothyroxine is recommended for long-term TSH suppression.

What cells or organs does TSH work on? 04/14/2023

Including thyroid,lymphocytes, the pituitary, thymus, testes, kidney, brain, adipose tissue, and fibroblasts.

What is the biological function of thyroid stimulating hormone (TSH)? 04/14/2023

The only established biologic function of thyroid stimulating hormone (TSH) is to regulate the synthesis and secretion of thyroid hormone from thyroid follicular cells.

How to achieve TSH transcription? 04/14/2023

In response to low circulating thyroid hormone levels, the basal medial hypothalamus releases thyrotropin-releasing hormone (TRH) which then stimulates production of thyroid-stimulating hormone (TSH) from the thyrotropes of the anterior pituitary gland.

Besides TSH, what other substances can stimulate the release of prolactin? 04/14/2023

Other substances like serotonin, gonadotropin-releasing hormone, and estrogen can also stimulate prolactin release.

What is the role of TSH protein in thyroid cancer? 12/24/2019

In thyroid cancer, the TSH protein may have a role in promoting the proliferation and growth of cancer cells. Therefore, for some high-risk groups, such as patients with postoperative thyroidectomy, inhibition of TSH protein production and activity can reduce the risk of cancer recurrence.

What factors regulate the secretion of TSH protein? 11/12/2019

The secretion of TSH protein is regulated by a variety of factors, including negative feedback regulation of the hypothalamic-pituitary-thyroid axis, thyroxine levels, and the regulatory mechanism of anterior pituitary cells.

Does the TSH protein have polymorphisms? 10/03/2019

The polymorphisms of the TSH protein are partly related to the genetic variation of individuals. TSH proteins of different genotypes may affect an individual's sensitivity to TSH and regulation of thyroid function.

How does TSH protein regulate thyroid function? 07/30/2019

TSH protein activates intracellular signaling pathways by binding to TSH receptors on the surface of thyroid cells, promoting thyroxine synthesis and secretion. It enhances the production of thyroxine by positively regulating iodine uptake, thyroglobulin synthesis, and thyroid peroxidase activity.

What are the applications of TSH protein in clinical diagnosis? 06/05/2019

The TSH protein plays a key role in clinical diagnosis. By measuring serum TSH levels, it is possible to assess whether the thyroid gland is functioning normally for diagnosis and follow-up of thyroid-related diseases.

Does the TSH protein interact with other proteins? 04/26/2019

Yes, the TSH protein can interact with TSH receptors on the surface of thyroid cells, triggering a series of signaling. In addition, TSH protein interacts with other cytokines and regulators to regulate thyroid function.

Customer Reviews (8)

Write a review

    Good for Bimo-lecular fluorescence complementation control.


      TSH manufacturer's products are consistently of the highest quality, with a strong commitment to purity, potency, and consistency.


        Work great in Western blot analysis.


          The purity is truly exceptional, with no visible impurities or contaminants.


            TSH is ideal for Western-blot analysis, with strong bands and clear specificity.


              Can save materials and shorten the experiment time in luci-ferase complementation assay.


                It was accurately quantified in expression analysis.


                  It is appropriate for T cell killing analysis.

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