As a leading biotechnology services supplier, Creative BioMart offers protein ubiquitinylation services. With our expertise as a leader in the field of ubiquitinylation services, Creative BioMart has created a set of new platform technologies.
Ubiquitin Screening Service
Creative BioMart provides compound screening and profiling against E3 ligase cascades. Each ubiquitination cascade consists of the three enzyme components (E1 activating enzyme, E2 conjugating enzyme and E3 ligase), plus a biologically-relevant substrate. The incorporation of ubiquitin into the substrate is quantitatively detected by electrochemiluminescence, which allows for the identification of compound inhibitors and activators.
Ubiquitin E3 Ligase Identification Service
Creative BioMart employs a high-content microarray and ubiquitin pathway expertise to identify candidate E3's that are capable of ubiquitylating your substrate
The service includes the following steps:
Creative BioMart can advise on the selection of the most appropriate scheme for the experiment. We have been performed successfully with protein ubiquitinylation services.
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