ASCL4
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Official Full Name
achaete-scute complex homolog 4
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Overview
Basic helix-loop-helix transcription factors, such as ASCL4, are essential for the determination of cell fate and the;development and differentiation of numerous tissues (Jonsson et al., 2004 (PubMed 15475265)). -
Synonyms
ASCL4; achaete-scute complex homolog 4 (Drosophila); achaete scute complex like 4 (Drosophila); achaete-scute homolog 4; bHLHa44; HASH4; ASH-4; class II bHLH protein ASCL4; achaete-scute complex-like 4; achaete-scute-like protein 4; class A basic helix-lo;
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | ASCL4-9927H | Recombinant Human ASCL4, GST-tagged | E.coli | GST | 1-70a.a. |
- Involved Pathway
- Protein Function
- Interacting Protein
- ASCL4 Related Articles
ASCL4 involved in several pathways and played different roles in them. We selected most pathways ASCL4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ASCL4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
ASCL4 has several biochemical functions, for example, DNA binding, protein binding, protein dimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ASCL4 itself. We selected most functions ASCL4 had, and list some proteins which have the same functions with ASCL4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| DNA binding | HIST2H2L;ZNF615;PRIM2;HOXD3;ZNF225;SIX4A;PALB2;RREB1;BSX |
| protein binding | TTLL10;BEND3;EIF4EBP3L;OS9;KLC1;DAG1;LRRC4B;ITGA6;PRKCD |
| protein dimerization activity | GARS;MYCL1;CELSR1;HEY2;MGAA;SIM1;TAL2;PRDX5;SREBF1 |
ASCL4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ASCL4 here. Most of them are supplied by our site. Hope this information will be useful for your research of ASCL4.
TCF4; TCF12; CRK
- Q&As
- Reviews
Q&As (4)
Ask a questionYes, ASCL4 can interact with several other proteins to regulate its activity and downstream signaling pathways. Some known interacting proteins include Groucho/TLE family members and histone deacetylases.
While ASCL4 shows promise as a potential therapeutic target for neurological disorders, more research is needed to investigate its mechanisms of action and the potential consequences of manipulating its activity.
ASCL4 acts as a transcription factor, binding to specific DNA sequences in the genome and regulating the expression of target genes involved in neuronal development and differentiation.
Currently, there is limited knowledge about the involvement of ASCL4 in diseases. More research is needed to understand its potential role in neurological disorders.
Customer Reviews (3)
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The manufacturer's commitment to customer satisfaction is unmatched.
Their prompt and insightful responses to inquiries and troubleshooting requests enable me to tackle experimental obstacles with confidence and efficiency.
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