Akp3
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Official Full Name
alkaline phosphatase 3, intestine, not Mn requiring
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Mouse | Akp3-565M | Recombinant Mouse Akp3 Protein, MYC/DDK-tagged | HEK293T | MYC/DDK |
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Akp3 involved in several pathways and played different roles in them. We selected most pathways Akp3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with Akp3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Akp3 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by Akp3 itself. We selected most functions Akp3 had, and list some proteins which have the same functions with Akp3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Akp3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Akp3 here. Most of them are supplied by our site. Hope this information will be useful for your research of Akp3.
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Q&As (15)
Ask a questionAlkaline phosphatase 3 (Akp3) is also widely used in bioscience research, such as as a marker or a catalyst for enzyme Catalysis reaction processes in cell or molecular biology research.
There are several methods for the determination of Akp3, such as biochemical detection, GC-MS detection, HPLC detection
The decrease of Akp3 may be caused by anemia, immunosuppressive therapy, acidosis and other factors.
In the field of drug development, Akp3 often plays an important role. In clinical drug safety evaluation, inhibition of Akp3 is regarded as an important indicator to identify drug toxicity. Therefore, the detection and analysis of Akp3 is of great significance in the evaluation of drug toxicity and side effects.
The results of Akp3 testing need to be analyzed in combination with clinical symptoms and other test results, such as the magnitude and duration of the increase or decrease.
Focusing on Akp3 during pregnancy can help clinicians detect liver damage and hepatitis in pregnant women and avoid potential complications and severe pregnancy reactions. In addition, Akp3 is also used in the study and diagnosis of rheumatoid arthritis, autoimmune diseases, anemia and kidney diseases.
In the field of genetics, using Akp3 to compare the genomes of different species can lay the foundation for biological and evolutionary studies, such as the study of Akp3 differences in mice and humans. Analysis of Akp3 in different animal species can also provide useful insights into the origin of human gene flow, population migration, and lineage structure.
Yes, Akp3 detection can help doctors judge the diagnosis and treatment effect of liver, lung, bone, intestinal and other diseases, and help to monitor and predict the development and prognosis of diseases such as liver and gallbladder diseases, abnormal bone metabolism and malignant tumors.
Akp3 is more specific than other isoenzymes in the bones, liver and placenta of adults and is therefore commonly used to detect disease in these tissues. Intestinal and hepatic ALP1 and ALP2, however, are less specific because they are present in a variety of tissues.
Akp3 is mainly found in bone and liver tissue and is often used in the diagnosis of bone metabolism and hepatobiliary diseases. Intestinal ALP1 mainly existed in intestinal mucosal epithelial cells. Hepatic ALP2 was distributed in liver, biliary tract, placenta and lung tissue. In addition, fetal ALP (fALP) is present only during pregnancy.
The role of Akp3 is to participate in the metabolic process of human bone, in which phosphatase is mainly produced by bone cells. Bone cells are divided into ossified cells and bone resorption cells, which are the main part of bone mineralization and regeneration. In the process of bone mineralization, alkaline phosphatase excreted by bone cells preferentially converts calcium dihydrogen phosphate into calcium trihydrogen phosphate. During bone resorption, bone cells release alkaline phosphatase, which encourages osteolytic cells to engulf bone tissue for use in bone mineralization and regeneration.
The detection of ALP has a wide range of applications in the diagnosis and monitoring of liver and gallbladder diseases, bone metabolism abnormalities, intestinal diseases and pregnancy-related diseases. Usually facial redness, nausea, vomiting and other symptoms in the body may indicate that the ALP content in our body is too high, and timely medical examination is needed
The test for Akp3 requires a blood test, and the collection and storage of blood requires care to avoid sample contamination.
Due to bone injury or disease, high concentration of Akp3 contained in osteoblasts is released into the blood, resulting in increased serum Akp3 activity. Such as fibrous osteitis, osteogenesis imperfecta, rickets, osteomalacia, bone metastasis cancer and fracture repair and healing period.
Alkaline phosphatase 3 (Akp3) is mainly used in the medical and biological sciences. In clinical tests, ALP is a very important biochemical index, which is widely used in the diagnosis and monitoring of liver and gallbladder diseases, bone metabolism abnormalities, intestinal diseases and pregnancy-related diseases.
Customer Reviews (3)
Write a reviewHigh purity and no significant impurities.
Relatively active and able to efficiently perform the required biological activity experiments.
The expression level was high enough to meet the experimental requirements.
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