brpf3
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  • Official Full Name
  • bromodomain and PHD finger containing, 3
  • Synonyms
  • BRPF3; bromodomain and PHD finger containing, 3; bromodomain and PHD finger-containing protein 3; KIAA1286; Bromodomain and PHD finger containing protein 3
Cat.#:BRPF3-160HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human BRPF3, GST-tagged
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Cat.#:BRPF3-26105THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human BRPF3, His-tagged
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Cat.#:BRPF3-60HTag:GST
Source (Host):E.coliSpecies:Human
Product nameRecombinant Human BRPF3 protein, GST-tagged
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Cat.#:BRPF3-61HTag:His
Source (Host):E.coliSpecies:Human
Product nameRecombinant Human BRPF3 protein, His-tagged
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Cat.#:BRPF3-182HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human BRPF3 cell lysate
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Cat.#:Kit-1703Tag:
Source (Host):Species:
Product nameBRPF3 Inhibitor Screening Assay Kit
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Cat.#:Kit-1704Tag:
Source (Host):Species:
Product nameBRPF3 TR-FRET Assay Kit
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Involved Pathway

BRPF3 involved in several pathways and played different roles in them. We selected most pathways BRPF3 participated on our site, such as Chromatin modifying enzymes, Chromatin organization, HATs acetylate histones, which may be useful for your reference. Also, other proteins which involved in the same pathway with BRPF3 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Chromatin modifying enzymes
PRMT6; KAT6A; ARID4A; ARID1A; USP22; MBD3; ING5B; ACTL6A; ZZZ3; ING5
Chromatin organization
KANSL3; MBD3B; MBD3; ATXN7L3; RBBP4; KANSL2; ELP3; SMARCD3; PBRM1L; MSL3
HATs acetylate histones
KAT7; ING5B; BRD8; TADA2B; TADA3; PHF17; EP400; MSL2; DR1; ELP4
Hemostasis
MERTK; MAFGA; IGF2B; MFN2; SH2B3; CD9B; HBD; SIRPA; CABLES1; HBB-Y
Platelet activation, signaling and aggregation
IGF2B; C6orf25; ABHD12; PDPN; SPARC; GAS6; RHOGA; AASS; STXBP3; WDR1
Platelet degranulation
PLEK; MMRN1; CALU; F13A1A.1; F13A1B; BRPF3; CLU; GAS6; CAP1; SRGN
Response to elevated platelet cytosolic Ca2+
MMRN2A; SRGN; SPARC; CAP1; STXBP3A; CD9B; MMRN1; STXBP3; SCG3; IGF2B

Protein Function

BRPF3 has several biochemical functions, for example, protein binding, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BRPF3 itself. We selected most functions BRPF3 had, and list some proteins which have the same functions with BRPF3. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein SHISA3; TOR1A; SCN5A; PARD3; DIRAS3; RARRES2; PYYA; CCDC25; COMMD6; CDT1
Function zinc ion binding
Related Protein CDA; PAPLNB; KAT7A; MMP30; RNF44; ZSWIM3; HE1B; TRIM50; AKT1S1; TADA2A

Interacting Protein

BRPF3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BRPF3 here. Most of them are supplied by our site. Hope this information will be useful for your research of BRPF3.
ABL1; FYN; NCK1; PIK3R1; GRB2; pdpC2; q7chb4_yerpe; opuD; WEE1; Mad2l1

BRPF3 Related Articles

Demont, EH; Bamborough, P; et al. 1,3-Dimethyl Benzimidazolones Are Potent, Selective Inhibitors of the BRPF1 Bromodomain. ACS MEDICINAL CHEMISTRY LETTERS 5:1190-1195(2014).
Lubula, MY; Poplawaski, A; et al. Crystallization and preliminary X-ray diffraction analysis of the BRPF1 bromodomain in complex with its H2AK5ac and H4K12ac histone-peptide ligands. ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS 70:1389-1393(2014).