caspa
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Cat.#:CASPA-9054ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish CASPA
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Involved Pathway

CASPA involved in several pathways and played different roles in them. We selected most pathways CASPA participated on our site, such as NOD-like receptor signaling pathway, Cytosolic DNA-sensing pathway, Salmonella infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with CASPA were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
NOD-like receptor signaling pathway
CXCL8B.3; MAPK14A; BIRC3; TRIP6; MAP3K7; CARD9; MAPK8B; NLRP3; PSTPIP1A; IKBKB
Cytosolic DNA-sensing pathway
ZBP1; POLR3GLB; IKBKG; CASPA; POLR3E; IFNA4; POLR3GL; IFNPHI1; NFKBIA; IFNA17
Salmonella infection
CDC42L; ROCK2; TLR4BA; CCL3L1; CCL3L3; NOS2; IL8L2; FLNA; CCL3; TLR5

Protein Function

CASPA has several biochemical functions, for example, Pyrin domain binding, cysteine-type endopeptidase activity, NOT cysteine-type endopeptidase activity involved in execution phase of apoptosis. Some of the functions are cooperated with other proteins, some of the functions could acted by CASPA itself. We selected most functions CASPA had, and list some proteins which have the same functions with CASPA. You can find most of the proteins on our site.
Function
Related Protein
Function Pyrin domain binding
Related Protein PYCARD; CASPA; NLRP2
Function cysteine-type endopeptidase activity
Related Protein BLMH; CTSL.1; USP9; USP27X; CASP8L1; USP19; CTSM; USP34; CTSSA; USP37
Function NOT cysteine-type endopeptidase activity involved in execution phase of apoptosis
Related Protein CASP1; CASPA; CASP5; CASPB; PSD; CASP4; CASP12; CASPBL
Function cysteine-type peptidase activity
Related Protein OTUD4; CASP8L1; CTSW; SOLH; CLCA3; CTSL.1; OTUD7A; CTSZ; USPL1; CTSL2
Function hydrolase activity
Related Protein EXO5; PDE5AB; CTSLL; ABHD8; MEST; CAPN2A; PTPRUB; DDX39AA; PPP4CB; ZRANB3
Function peptidase activity
Related Protein USP25; PRSS44; KLK1B5; BMP1A; DHH; MMP23BB; CASP3A; ASTL; Ctsl; KLK1B9

Interacting Protein

CASPA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CASPA here. Most of them are supplied by our site. Hope this information will be useful for your research of CASPA.
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