depdc6
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  • Official Full Name
  • DEP domain containing MTOR-interacting protein
  • Background
  • DEP domain-containing mTOR-interacting protein (DEPTOR) also known as DEP domain-containing protein 6 (DEPDC6) is a protein that in humans is encoded by the DEPTOR gene.
  • Synonyms
  • DEP.6; DEPDC6; FLJ12341; FLJ12428; FLJ13854; DKFZp564B1778; DEP domain-containing mTOR-interacting protein; OTTHUMP00000228295; OTTHUMP00000228296; DEP domain containing 6; DEP domain-containing protein 6; DEP domain containing mTOR interacting protein
Cat.#:DEPDC6-4348CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken DEPDC6
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Cat.#:DEPDC6-6973HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human DEPDC6 293 Cell Lysate
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Involved Pathway

DEPDC6 involved in several pathways and played different roles in them. We selected most pathways DEPDC6 participated on our site, such as Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met), mTOR signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with DEPDC6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
MUC20; DEPDC6
mTOR signaling pathway
PIK3CB; INS; EIF4BB; CAB39; PTENB; RPS6KB1; RPS6KA3B; PRKCBA; RRAGCB; CAB39L

Protein Function

DEPDC6 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DEPDC6 itself. We selected most functions DEPDC6 had, and list some proteins which have the same functions with DEPDC6. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein ASF1B; SPTSSA; CYTH3; PTGFRN; POLR2E; SET; RGP1; PIK3C3; MRFAP1; RPS27

Interacting Protein

DEPDC6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DEPDC6 here. Most of them are supplied by our site. Hope this information will be useful for your research of DEPDC6.
RICTOR; RPTOR; TRAF1; CCDC110; MTOR; Mtor

DEPDC6 Related Articles

Caron, A; Baraboi, ED; et al. DEP Domain-Containing mTOR-Interacting Protein in the Rat Brain: Distribution of Expression and Potential Implication. JOURNAL OF COMPARATIVE NEUROLOGY 523:93-107(2015).
Davies, J; Zachariades, E; et al. Elucidating the role of DEPTOR in Alzheimer's disease. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 34:1195-1200(2014).