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GABRR1

  • Official Full Name

    gamma-aminobutyric acid (GABA) receptor, rho 1

  • Overview

    GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA receptors, which are ligand-gated chloride channels. GABRR1 is a member of the rho subunit family.
  • Synonyms

    GABRR1; gamma-aminobutyric acid (GABA) receptor, rho 1; gamma-aminobutyric acid receptor subunit rho-1; bA135P14.1 (gamma-aminobutyric acid (GABA) receptor rho 1); GABA(A) receptor subunit rho-1; gamma aminobutyric acid receptor rho 1; gamma-aminobutyric acid (GABA) A receptor rho-1; gamma-aminobutyric acid (GABA) receptor rho 1; MGC163216; GABA(C) receptor; OTTHUMP00000016849; OTTHUMP00000209035; gamma-aminobutyric acid (GABA) A receptor, rho-1; bA135P14.1 (gamma-aminobutyric acid (GABA) receptor, rho 1);

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • His
  • His (Fc)
  • Avi
  • N/A
  • N
  • GST
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GABRR1-4651H Recombinant Human GABRR1 Protein Wheat Germ N/A
Human GABRR1-1555H Recombinant Human GABRR1 Protein, His&GST-tagged E.coli N-His&GST Thr22-Ile281
Human GABRR1-5202HF Recombinant Full Length Human GABRR1 Protein In Vitro Cell Free System 217 amino acids
Mouse GABRR1-6159M Recombinant Mouse GABRR1 Protein Mammalian Cell His
Mouse GABRR1-3437M Recombinant Mouse GABRR1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse GABRR1-3437M-B Recombinant Mouse GABRR1 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish GABRR1-3165Z Recombinant Zebrafish GABRR1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • GABRR1 Related Articles
  • GABRR1 Related Research Area

GABRR1 involved in several pathways and played different roles in them. We selected most pathways GABRR1 participated on our site, such as Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, which may be useful for your reference. Also, other proteins which involved in the same pathway with GABRR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Neuroactive ligand-receptor interactionGRIA1B;F2RL1.2;PTH1RB;PTGER2B;APLNRB;GRM1;GRIN1B;S1PR4;TAAR7D
Retrograde endocannabinoid signalingGABRA2;GABRR2;GABRB2;GABRB3;GNAI1;GNG2;MAPK8;GNB3;MAPK10
GABAergic synapseGNGT1;GABARAPL1;GNGT2;GNG4;SLC12A5;GNG13;GABARAPL2;GABRG3;GABARAP
Nicotine addictionGABRR1;SLC17A7;GABRE;GRIA3;GABRA2;GABRA5;GABRA4;GRIN2A;GRIN2B

GABRR1 has several biochemical functions, for example, GABA receptor activity, GABA-A receptor activity, chloride channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GABRR1 itself. We selected most functions GABRR1 had, and list some proteins which have the same functions with GABRR1. You can find most of the proteins on our site.

Function Related Protein
GABA receptor activity
GABA-A receptor activityGABRA6A;GABRG2;GABRB1;GABRR1;GABRR3;GABRR2;GABRB2;GABRD;GABRB3
chloride channel activityGABRE;SLC26A11;FXYD3;CLIC6;CFTR;SLC26A6;SLC26A3.1;CLCC1;CLIC5B
extracellular ligand-gated ion channel activityGABRD;CHRNB3;GABRR3;CHRNB1L;GABRZ;SIX2A;GABRR3A;CHRNB3A;GLRA4B
protein domain specific bindingYWHAB;TWIST1;ST13;DBNL;XPA;STX1A;NEDD4;COX4I2;YWHAE1
protein heterodimerization activityCABYR;KCNH1;H3F3B.1;TIRAP;DLG4B;HIST1H2AA;PEF1;SYT16;HEXA
protein homodimerization activityGSS;NR0B1;TMEM173;ATPIF1;GOLGA5;TERT;TG;LRP4;HM13

GABRR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GABRR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GABRR1.

Santoro, ML; Ota, VK; et al. Effect of antipsychotic drugs on gene expression in the prefrontal cortex and nucleus accumbens in the spontaneously hypertensive rat (SHR). SCHIZOPHRENIA RESEARCH 157:163-168(2014).
Do, DN; Strathe, AB; et al. Genome-Wide Association Study Reveals Genetic Architecture of Eating Behavior in Pigs and Its Implications for Humans Obesity by Comparative Mapping. PLOS ONE 8:-(2013).
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