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Official Full Name GIPC PDZ domain containing family, member 1
Background GIPC1 is a scaffolding protein that regulates cell surface receptor expression and trafficking (Lee et al., 2008;(PubMed 18775991)).
Synonyms GIPC1; GIPC PDZ domain containing family, member 1; C19orf3, chromosome 19 open reading frame 3 , regulator of G protein signalling 19 interacting protein 1 , RGS19IP1; PDZ domain-containing protein GIPC1; GIPC; GLUT1CBP; Hs.6454; NIP; SEMCAP; SYNECTIN; TIP 2; C19ORF3; Chromosome 19 open reading frame 3; GLUT1 C terminal binding protein; IGF 1 receptor interacting protein 1; IIP 1; IIP1; Regulator of G protein signalling 19 interacting protein 1; RGS19 interacting protein 1; RGS19IP1; SYNECTIIN; Tax interaction protein 2; RGS19-interacting protein 1; RGS-GAIP-interacting protein; GLUT1 C-terminal binding protein; GAIP C-terminus-interacting protein; IGF-1 receptor interacting protein 1; regulator of G-protein signalling 19 interacting protein 1; IIP-1; TIP-2
    • Species :
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc
    • DDK
    • N/A
    • T7
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human GIPC1-001H Recombinant Human GIPC1 Protein, His-tagged E.coli His
    Human GIPC1-002H Recombinant Human GIPC1 Protein, His-tagged E.coli His
    Human GIPC1-003H Recombinant Human GIPC1 Protein, MYC/DDK-tagged HEK293T Myc/DDK
    Human GIPC1-004H Recombinant Human GIPC1 Protein, MYC/DDK-tagged HEK293T Myc/DDK
    Human GIPC1-005H Recombinant Human GIPC1 Protein, MYC/DDK-tagged HEK293T Myc/DDK
    Human GIPC1-2897H Recombinant Human GIPC1, T7-tagged E.coli T7
    Human GIPC1-29065TH Recombinant Human GIPC1, His-tagged E.coli His
    Human GIPC1-4913H Recombinant Human GIPC1 Protein, GST-tagged Wheat Germ GST
    Human GIPC1-5928HCL Recombinant Human GIPC1 293 Cell Lysate HEK293 N/A
    Mouse GIPC1-6363M Recombinant Mouse GIPC1 Protein Mammalian Cell His
    Rat GIPC1-2541R Recombinant Rat GIPC1 Protein Mammalian Cell His
    Zebrafish GIPC1-1216Z Recombinant Zebrafish GIPC1 Mammalian Cell His

    GIPC1 involved in several pathways and played different roles in them. We selected most pathways GIPC1 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with GIPC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Neurotrophic factor-mediated Trk receptor signaling RGS19; DYNLT1; RIT1; MCF2L; FAIM; GIPC1; RIT2
    Syndecan-4-mediated signaling events ADAM12; GIPC1; MDK
    TGF-beta Receptor Signaling Pathway ZEB2A; EID2; SKIA; ZEB1B; ACVRL1; NFYBB; FOXH1; RUNX2A; JUNBA; TRAP1

    GIPC1 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by GIPC1 itself. We selected most functions GIPC1 had, and list some proteins which have the same functions with GIPC1. You can find most of the proteins on our site.

    Function Related Protein
    PDZ domain binding Apba1; SRR; TBC1D10A; SNTB1; ERC1; PLEKHA2; PTENB; ARHGAP29; MAP2K2; CXXC4
    actin binding PTK2; KLHL20; MYH1E; RUSC1; MYH1; MYO19; CNN2; NCALD; ANTXR2A; INPPL1A
    myosin binding KIRREL; GIPC1; CALD1B; FXYD1; STX4A; RHOA; SLC6A4; ACTC1; NPHS1; VAMP2
    protein binding PTGIS; MTSS1; MED17; STATH; BNIP1; ACVR2A; KLF11; TAF9B; TRIM27; C11orf65
    protein homodimerization activity JUP; FZD1; STUB1; PITX2; CHMP4A; SLC14A2; ADH5; ABAT; PAFAH1B1; SOD1
    receptor binding FASLG; EDN3; GUSB; CRAT; APOF; CADM1B; NRG3; PVRL2; PLA2G1B; F2R

    GIPC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GIPC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GIPC1.

    E6; TYRP1; TGFBR3; TPBG; 42734339; MYO1C; BCR; PRKCA; SDC4; MCM7; COPB2; SSR4

    Sensoy, O; Weinstein, H; et al. A mechanistic role of Helix 8 in GPCRs: Computational modeling of the dopamine D2 receptor interaction with the GIPC1-PDZ-domain. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES 1848:976-983(2015).
    Solomon, O; Bazak, L; et al. Characterizing of functional human coding RNA editing from evolutionary, structural, and dynamic perspectives. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS 82:3117-3131(2014).

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