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GIPC1

  • Official Full Name

    GIPC PDZ domain containing family, member 1

  • Overview

    GIPC1 is a scaffolding protein that regulates cell surface receptor expression and trafficking (Lee et al., 2008;(PubMed 18775991)).
  • Synonyms

    GIPC1; GIPC PDZ domain containing family, member 1; C19orf3, chromosome 19 open reading frame 3 , regulator of G protein signalling 19 interacting protein 1 , RGS19IP1; PDZ domain-containing protein GIPC1; GIPC; GLUT1CBP; Hs.6454; NIP; SEMCAP; SYNECTIN; TIP 2; C19ORF3; Chromosome 19 open reading frame 3; GLUT1 C terminal binding protein; IGF 1 receptor interacting protein 1; IIP 1; IIP1; Regulator of G protein signalling 19 interacting protein 1; RGS19 interacting protein 1; RGS19IP1; SYNECTIIN; Tax interaction protein 2; RGS19-interacting protein 1; RGS-GAIP-interacting protein; GLUT1 C-terminal binding protein; GAIP C-terminus-interacting protein; IGF-1 receptor interacting protein 1; regulator of G-protein signalling 19 interacting protein 1; IIP-1; TIP-2;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • T7
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GIPC1-29065TH Recombinant Human GIPC1, His-tagged E.coli His 333 amino acids
Human GIPC1-2897H Recombinant Human GIPC1, T7-tagged E.coli T7
Human GIPC1-5928HCL Recombinant Human GIPC1 293 Cell Lysate HEK293 N/A
Human GIPC1-4913H Recombinant Human GIPC1 Protein, GST-tagged Wheat Germ GST
Human GIPC1-1359H Recombinant Human GIPC1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human GIPC1-005H Recombinant Human GIPC1 Protein, MYC/DDK-tagged HEK293T Myc/DDK
Human GIPC1-001H Recombinant Human GIPC1 Protein, His-tagged E.coli His
Human GIPC1-2651H Recombinant Human GIPC1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human GIPC1-002H Recombinant Human GIPC1 Protein, His-tagged E.coli His
Human GIPC1-4230H Recombinant Human GIPC1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human GIPC1-003H Recombinant Human GIPC1 Protein, MYC/DDK-tagged HEK293T Myc/DDK
Human GIPC1-5276HF Recombinant Full Length Human GIPC1 Protein, GST-tagged In Vitro Cell Free System GST 333 amino acids
Human GIPC1-004H Recombinant Human GIPC1 Protein, MYC/DDK-tagged HEK293T Myc/DDK
Mouse GIPC1-6363M Recombinant Mouse GIPC1 Protein Mammalian Cell His
Mouse GIPC1-3565M Recombinant Mouse GIPC1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse GIPC1-3565M-B Recombinant Mouse GIPC1 Protein Pre-coupled Magnetic Beads HEK293
Mouse Gipc1-3213M Recombinant Mouse Gipc1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat GIPC1-2541R Recombinant Rat GIPC1 Protein Mammalian Cell His
Rat GIPC1-2197R Recombinant Rat GIPC1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat GIPC1-2197R-B Recombinant Rat GIPC1 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish GIPC1-1216Z Recombinant Zebrafish GIPC1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • GIPC1 Related Articles

GIPC1 involved in several pathways and played different roles in them. We selected most pathways GIPC1 participated on our site, such as Neurotrophic factor-mediated Trk receptor signaling, Syndecan-4-mediated signaling events, TGF-beta Receptor Signaling Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with GIPC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Neurotrophic factor-mediated Trk receptor signalingDYNLT1;FAIM;RIT1;GIPC1;RIT2;RGS19;MCF2L
Syndecan-4-mediated signaling eventsGIPC1;MDK;ADAM12
TGF-beta Receptor Signaling PathwayENG;STAMBPL1;EID2;ZEB1B;JUNBA;DAB2;TGFBR3;NFYBB;COPS5

GIPC1 has several biochemical functions, for example, PDZ domain binding, actin binding, myosin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GIPC1 itself. We selected most functions GIPC1 had, and list some proteins which have the same functions with GIPC1. You can find most of the proteins on our site.

Function Related Protein
PDZ domain bindingDLG3;PLEKHA1;NLGN1;SNTB1;ATP2B3A;TGFBR3;NSF;PSEN1;SLC9A3R2
actin bindingMYO6;SLC4A1;FMN1;SNTB1;SPTBN2;LMOD1;PXK;GIPC1;GSN
myosin bindingCALD1;USH2A;ACTA1;KIRREL;SMYD1B;SLC6A4;ACTC1;CALM;DMD
protein bindingSNRPD1;USP12;APEX1;KDM2B;ITGB4;KLHL20;RAB7L1;KLK6;ARHGEF7
protein homodimerization activityRRAGA;G6PD;UXS1;DPY30;VOX;BHLHA15;RAP1GAP;MYH7;ZBTB4
receptor bindingCTNND1;LIF;NRG2B;DPP4;MATK;HAO2;NRXN1;PEX14;IL28A

GIPC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GIPC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GIPC1.

E6; TYRP1; TGFBR3; TPBG; 42734339; MYO1C; BCR; PRKCA; SDC4; MCM7; COPB2; SSR4

Sensoy, O; Weinstein, H; et al. A mechanistic role of Helix 8 in GPCRs: Computational modeling of the dopamine D2 receptor interaction with the GIPC1-PDZ-domain. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES 1848:976-983(2015).
Solomon, O; Bazak, L; et al. Characterizing of functional human coding RNA editing from evolutionary, structural, and dynamic perspectives. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS 82:3117-3131(2014).
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