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GRWD1

Official Full Name

glutamate-rich WD repeat containing 1
Overview

This gene encodes a glutamate-rich protein that contains five WD-repeat motifs. The encoded protein may play a critical;role in ribosome biogenesis and may also play a role in histone methylation through interactions with CUL4-DDB1;ubiquitin E3 ligase.
Synonyms

GRWD1; glutamate-rich WD repeat containing 1; glutamate-rich WD repeat-containing protein 1; GRWD; regulator of ribosome biogenesis 1 homolog (S. cerevisiae); RRB1; WDR28; Glutamate rich WD repeat containing 1; Glutamate rich WD repeat containing protein 1; Glutamate rich WD repeat protein GRWD; GRWD 1; KIAA1942; Regulator of ribosome biogenesis 1 homolog; RRB 1; WD repeat domain 28; WDR 28; CUL4- and DDB1-associated WDR protein 4; CDW4;

Type

Cell & Tissue Lysates
Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Rat
Zebrafish

Source

HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	GRWD1-5729HCL	Recombinant Human GRWD1 293 Cell Lysate	HEK293	N/A		Inquiry
Human	GRWD1-5615HF	Recombinant Full Length Human GRWD1 Protein, GST-tagged	In Vitro Cell Free System	GST	446 amino acids	Inquiry
Human	GRWD1-5386H	Recombinant Human GRWD1 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Rat	GRWD1-2725R	Recombinant Rat GRWD1 Protein	Mammalian Cell	His		Inquiry
Rat	GRWD1-2379R-B	Recombinant Rat GRWD1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	GRWD1-2379R	Recombinant Rat GRWD1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Zebrafish	GRWD1-950Z	Recombinant Zebrafish GRWD1	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
GRWD1 Related Articles

GRWD1 involved in several pathways and played different roles in them. We selected most pathways GRWD1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with GRWD1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

GRWD1 has several biochemical functions, for example, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GRWD1 itself. We selected most functions GRWD1 had, and list some proteins which have the same functions with GRWD1. You can find most of the proteins on our site.

Function	Related Protein
poly(A) RNA binding	MYO5A;ZFP36;SYNCRIP;DSP;PURB;ALDOA;UBE2N;UBAP2L;RPS27A

GRWD1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GRWD1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GRWD1.

CUL4B; MAP3K14; midostaurin; ssrna_ug; GABARAP; MNDA; HDGF; GABARAPL2; WDR5; GRB2; CUL4A; WDR5B; RFWD2; SNRNP40; GABARAPL1

Gratenstein, K; Heggestad, AD; et al. The WD-repeat protein GRWD1: Potential roles in myeloid differentiation and ribosome biogenesis. GENOMICS 85:762-773(2005).