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Gabra2

  • Official Full Name

    gamma-aminobutyric acid (GABA) A receptor, alpha 2

  • Synonyms

    GABRA2; gamma-aminobutyric acid (GABA) A receptor, alpha 2; gamma-aminobutyric acid receptor subunit alpha-2; GABA(A) receptor; alpha 2; GABA(A) receptor, alpha 2; GABA(A) receptor subunit alpha-2; FLJ97076;

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • His
  • His (Fc)
  • Avi
  • His|GST
  • N/A
  • N
  • GST
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GABRA2-6066HCL Recombinant Human GABRA2 293 Cell Lysate HEK293 N/A
Human GABRA2-4636H Recombinant Human GABRA2 Protein Wheat Germ N/A
Human GABRA2-388H Recombinant Human GABRA2 Protein, His/GST-tagged E.coli His/GST Phe42~Ile250
Human GABRA2-5183HF Recombinant Full Length Human GABRA2 Protein In Vitro Cell Free System 190 amino acids
Human GABRA2-2535H Recombinant Human GABRA2 Protein (Phe42-Ile250), N-GST tagged E.coli N-GST Phe42-Ile250
Mouse GABRA2-6145M Recombinant Mouse GABRA2 Protein Mammalian Cell His
Mouse GABRA2-3428M-B Recombinant Mouse GABRA2 Protein Pre-coupled Magnetic Beads HEK293
Mouse GABRA2-3428M Recombinant Mouse GABRA2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque GABRA2-1793R Recombinant Rhesus monkey GABRA2 Protein, His-tagged Mammalian Cell His
Rhesus Macaque GABRA2-1614R Recombinant Rhesus Macaque GABRA2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque GABRA2-1614R-B Recombinant Rhesus Macaque GABRA2 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Gabra2 Related Articles
  • Gabra2 Related Research Area

Gabra2 involved in several pathways and played different roles in them. We selected most pathways Gabra2 participated on our site, such as Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, which may be useful for your reference. Also, other proteins which involved in the same pathway with Gabra2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Neuroactive ligand-receptor interactionTAAR14H;MLNR;CHRNE;GNRHR;P2RY11;ADRB2B;AVPR2;TAAR10A;GRIN2A
Retrograde endocannabinoid signalingGABRG2;GNG10;GABRR3;GABRP;GRM1;GNB2;NAPEPLD;DAGLB;GABRA5
GABAergic synapseGNGT2;GNG11;PLCL1;GNG2;GABRQ;GNG13;GABRA4;GABRG3;GNG12
Nicotine addictionGRIA1;GABRG3;GRIN3B;SLC17A7;GRIN2D;GABRA1;GABRD;GABRE;GABRA6

Gabra2 has several biochemical functions, for example, contributes_to GABA-A receptor activity, benzodiazepine receptor activity, chloride channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Gabra2 itself. We selected most functions Gabra2 had, and list some proteins which have the same functions with Gabra2. You can find most of the proteins on our site.

Function Related Protein
contributes_to GABA-A receptor activityGABRZ;GABRR2A;GABRP;GABRG2;GABRR3A;GABRA5;GABRA4;GABRQ;GABRG1
benzodiazepine receptor activityGABRA4;GABRA2;GABRA3;TSPO;GABRA6;GABRG2
chloride channel activityGABRG1;TTYH2;CLCC1;GABRA1;CLIC1;SLC26A3.2;CLIC5;CFTR;CLCA1
inhibitory extracellular ligand-gated ion channel activityGABRA6A;GABRG2;GABRA5;GABRG1;GABRE;GABRG3;GABRA3;GABRA2;GABRA1

Gabra2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Gabra2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Gabra2.

MDM2

Jin, HB; Chiou, TT; et al. Ring Finger Protein 34 (RNF34) Interacts with and Promotes gamma-Aminobutyric Acid Type-A Receptor Degradation via Ubiquitination of the gamma 2 Subunit. JOURNAL OF BIOLOGICAL CHEMISTRY 289:29420-29436(2014).
Takano, K; Yatabe, MS; et al. Characteristic Expressions of GABA Receptors and GABA Producing/Transporting Molecules in Rat Kidney. PLOS ONE 9:-(2014).
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