helz2
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Cat.#:HELZ2-1047HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human HELZ2
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Involved Pathway

HELZ2 involved in several pathways and played different roles in them. We selected most pathways HELZ2 participated on our site, such as Activation of gene expression by SREBF (SREBP), BMAL1:CLOCK,NPAS2 activates circadian gene expression, Circadian Clock, which may be useful for your reference. Also, other proteins which involved in the same pathway with HELZ2 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Activation of gene expression by SREBF (SREBP)
MTF1; NFYAL; DHCR7; NFYBA; SREBF2; PMVK; CREBBP; HELZ2; CARM1; CYP51A1
BMAL1:CLOCK,NPAS2 activates circadian gene expression
CREBBP; NRIP1; NCOA2; NAMPT; DBP; HELZ2; CRY2; CARM1; CRY1
Circadian Clock
NAMPT; DBP; NRIP1; HELZ2; CPT1A; CRY1; RAI1; CSNK1E; CARM1; CRY2
Developmental Biology
PAK4; MYL12B; ACTR2B; COL6A3; SCN3B; JAK3; GDF1; SMAD3B; AP2A2; DOCK1
Fatty acid, triacylglycerol, and ketone body metabolism
MTF1; TIAM2; MED6; GLIPR1; G0S2; ACOT6; AGT; ACOT10; STIL; Agmo
Gene Expression
TNPO1; IGF2BP1; ZNF264; TSEN2; ZNF785; SMG8; ZFP1; ESRRGA; TYW1; COX7C
Generic Transcription Pathway
NR2F6; ZNF224; ZNF10; RRAGB; RRAGA; ZNF729; ZNF597; ZNF726; COX7C; ZNF213
Metabolism
ETFA; VAPB; NUDT5; IP6K3; NUDT3B; CTRC; NOSIP; CYP2K22; PLD6; CYP4T8

Protein Function

HELZ2 has several biochemical functions, for example, ATP binding, DNA binding, helicase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HELZ2 itself. We selected most functions HELZ2 had, and list some proteins which have the same functions with HELZ2. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein NOLC1; FGFR1A; CAMKK1A; CLCN4; STK38; ACSM2; CKBA; STRC; ATP1A3B; CARKD
Function DNA binding
Related Protein FOXD5; PPARGC1A; LYL1; FOXJ1; E2F5; SPHK1; ZNF3; NR6A1; ERCC3; FOXI3B
Function helicase activity
Related Protein DHX34; HELZ2; DHX36; SNRNP200; HLTF; PEO1; DDX19B; WRN; NAV2; DHX32A
Function ligand-dependent nuclear receptor transcription coactivator activity
Related Protein CARM1; CALCOCO1; PKN1; MED17; HMGA1; RBM14; ACTN4; ENY2; NCOA2; BUD31
Function metal ion binding
Related Protein ADAM1B; RASA4; ZNF75A; TET3; NME3; AGBL4; SEMG1; ZFP689; ZNF488; KLK1B4
Function poly(A) RNA binding
Related Protein YTHDC1; SR140; XRCC5; EZR; UCHL5; HMGB1; THRAP3; PWP2; RPL10A; MTIF2
Function protein binding
Related Protein FOXB1; EFCAB4A; IL7R; TAF6L; PYYA; RPP38; TRAF3; HLA-DRB3; BIN2; CDYL2

Interacting Protein

HELZ2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HELZ2 here. Most of them are supplied by our site. Hope this information will be useful for your research of HELZ2.
BCL6