helz2
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  • Synonyms
Cat.#:HELZ2-1047HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human HELZ2
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Involved Pathway

HELZ2 involved in several pathways and played different roles in them. We selected most pathways HELZ2 participated on our site, such as Activation of gene expression by SREBF (SREBP), BMAL1:CLOCK,NPAS2 activates circadian gene expression, Circadian Clock, which may be useful for your reference. Also, other proteins which involved in the same pathway with HELZ2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Activation of gene expression by SREBF (SREBP)
HELZ2; NFYBA; CARM1; MTF1; SREBF2; PMVK; NFYBB; NFYAL; CYP51A1; DHCR7
BMAL1:CLOCK,NPAS2 activates circadian gene expression
CARM1; NRIP1; NCOA2; DBP; CRY2; CREBBP; NAMPT; CRY1; HELZ2
Circadian Clock
HELZ2; CSNK1E; NAMPT; CRY1; DBP; NRIP1; CARM1; CRY2; RAI1; CPT1A
Developmental Biology
CAP2; CNKSR1; PAQR3A; SIAH2; KCNQ2; ARPC3; SREBF2; CARM1; MED20; MED26
Fatty acid, triacylglycerol, and ketone body metabolism
CTGF; ACOT12; MED6; GRHL1; MED8; ACOT9; AGPAT1; SREBF2; YAP1; ACSF2
Gene Expression
ZNF615; ASZ1; ZNF706; ANP32A; ZNF227; NT5C3B; EED; COX6A1; TAF1D; ZNF567
Generic Transcription Pathway
ZNF583; ZIK1; SKILB; RORAA; MED31; ZNF79; ZNF483; ZNF543; ZNF566; LRPPRC
Metabolism
AS3MT; GPAT2; ARL2BP; SLC25A15; AQP1A.1; PMVK; SLC52A3; COX11; SLC25A2; GGTLC1

Protein Function

HELZ2 has several biochemical functions, for example, ATP binding, DNA binding, helicase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HELZ2 itself. We selected most functions HELZ2 had, and list some proteins which have the same functions with HELZ2. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein NTRK3A; SPO11; CKM; CSNK2A1; DYRK1A; BMPR2A; PSMC1A; AURKB; CHD1; RAD54B
Function DNA binding
Related Protein HIST1H2BJ; RUNX1T1; ZFP513; ZNF596; MGMT; ETS2; STAT2; HOXC13B; PRDM2; ARNTL
Function helicase activity
Related Protein DDX6; HELQ; DHX37; MCM3L; HELZ; DDX11; RAD54L; GTF2F2A; CHD1L; SMARCAD1
Function ligand-dependent nuclear receptor transcription coactivator activity
Related Protein PPARG; MED4; TSG101; KDM1A; SS18; LRP2BP; CARM1; PSMC3IP; PUS1; SFR1
Function metal ion binding
Related Protein BCL11BA; KCND3; GM9524; Reln; OVOL3; ARSG; ZNF830; ALPL; ZC3H10; TATDN1
Function poly(A) RNA binding
Related Protein CEBPZ; ADAR; ZC3HAV1; RBM8A; ZC3H10; CSTF2T; CDC40; RBM15; FCF1; HIST1H4B
Function protein binding
Related Protein RBBP5; KLRB1F; NMI; IRF7; PABPC1; CCKBR; Fert2; C11orf49; GHRL; MUTED

Interacting Protein

HELZ2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HELZ2 here. Most of them are supplied by our site. Hope this information will be useful for your research of HELZ2.
BCL6