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HOMER2

  • Official Full Name

    homer homolog 2 (Drosophila)

  • Overview

    This gene encodes a member of the homer family of dendritic proteins. Members of this family regulate group 1 metabotrophic glutamate receptor function. The encoded protein is a postsynaptic density scaffolding protein. Alternative splicing results in multiple transcript variants. Two related pseudogenes have been identified on chromosome 14.
  • Synonyms

    HOMER2; homer homolog 2 (Drosophila); homer protein homolog 2; CPD; Cupidin; HOMER 2; HOMER 2A; HOMER 2B; Vesl 2; ACPD; HOME2_HUMAN; Homer homolog 3; Homer neuronal immediate early gene 2; Homer-2; HOMER2A; HOMER2B; Vesl2; homer, neuronal immediate early gene, 2; VESL-2;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • C
  • Myc
  • DDK
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HOMER2-13880H Recombinant Human HOMER2, GST-tagged E.coli GST C-term-300a.a.
Human HOMER2-4925H Recombinant Human HOMER2 Protein, GST-tagged Wheat Germ GST
Human HOMER2-5437HCL Recombinant Human HOMER2 293 Cell Lysate HEK293 N/A
Human HOMER2-1697H Recombinant Human HOMER2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human HOMER2-440H Recombinant Human HOMER2 Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
Human HOMER2-2252H Recombinant Human HOMER2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human HOMER2-5768H Recombinant Human HOMER2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human HOMER2-3689HF Recombinant Full Length Human HOMER2 Protein, GST-tagged In Vitro Cell Free System GST 343 amino acids
Mouse HOMER2-7776M Recombinant Mouse HOMER2 Protein Mammalian Cell His
Mouse Homer2-3426M Recombinant Mouse Homer2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse HOMER2-4269M-B Recombinant Mouse HOMER2 Protein Pre-coupled Magnetic Beads HEK293
Mouse HOMER2-4269M Recombinant Mouse HOMER2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat HOMER2-2888R Recombinant Rat HOMER2 Protein Mammalian Cell His
Rat HOMER2-2543R Recombinant Rat HOMER2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat HOMER2-2543R-B Recombinant Rat HOMER2 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish HOMER2-2809Z Recombinant Zebrafish HOMER2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • HOMER2 Related Articles
  • HOMER2 Related Research Area

HOMER2 involved in several pathways and played different roles in them. We selected most pathways HOMER2 participated on our site, such as FoxO signaling pathway, Glutamatergic synapse, which may be useful for your reference. Also, other proteins which involved in the same pathway with HOMER2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
FoxO signaling pathwayTGFB3;PIK3CD;PTENB;G6PCA.1;HRASA;SOS1;SOD2;IRS2;NLK
Glutamatergic synapseGRM3;GNG3;GNG13;GNG12;SLC1A7;GNG10;GNAO1;PLA2G4A;PLA2G4F

HOMER2 has several biochemical functions, for example, G-protein coupled glutamate receptor binding, GKAP/Homer scaffold activity, actin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HOMER2 itself. We selected most functions HOMER2 had, and list some proteins which have the same functions with HOMER2. You can find most of the proteins on our site.

Function Related Protein
G-protein coupled glutamate receptor bindingHOMER3;HOMER1;HOMER2;HOMER1B
GKAP/Homer scaffold activitySHANK3;HOMER2;SHANK1
actin bindingNF2;SMTNL;XIRP2;ABLIM2;MSRB2;HIP1R;PARVAA;TMSB;DMTN
protein bindingLRRC4C;PKN1;ILKAP;ITPKB;HDAC2;ADPRH;C16orf79;CACNG2;TPM1
protein domain specific bindingATN1;PICK1;UNC13A;ODF1;STRN4;PRKCI;ICA1L;Akap2;ATP1A1
protein heterodimerization activityPEF1;Itgam&Itgb2;HEXB;BDKRB2;HIST2H2BE;HNF1B;CENPW;H3F3B;CLCF1
protein homodimerization activityBMPR1A;IRAK1;ADD2;GAMT;MECOM;ZHX2;BST2;GLIPR2;PON1

HOMER2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HOMER2 here. Most of them are supplied by our site. Hope this information will be useful for your research of HOMER2.

LZTS2; RNF41; APP; KPNA2

Jing, X; Chen, SS; et al. Diagnostic Potential of Differentially Expressed Homer1, IL-1 beta, and TNF-alpha in Coronary Artery Disease. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 16:535-546(2015).
Gould, AT; Sacramento, AD; et al. Cocaine-elicited imbalances in ventromedial prefrontal cortex Homer1 versus Homer2 expression: implications for relapse. ADDICTION BIOLOGY 20:148-157(2015).
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