ifit3
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  • Official Full Name
  • interferon-induced protein with tetratricopeptide repeats 3
  • Background
  • Interferon-induced protein with tetratricopeptide repeats 3 is a protein that in humans is encoded by the IFIT3 gene.
  • Synonyms
  • IFIT3; interferon-induced protein with tetratricopeptide repeats 3; IFIT4, interferon induced protein with tetratricopeptide repeats 4; CIG 49; GARG 49; IFI60; IRG2; ISG60; RIG G; RP11-149I23.4; CIG49; IFI-60K; IFI60K; IFIT-3; IFIT-4; IFIT3_HUMAN; IFIT4; Interferon induced 60 kDa protein; Interferon induced protein with tetratricopeptide repeats 3; Interferon-induced 60 kDa protein; Interferon-induced protein with tetratricopeptide repeats 4; ISG-60; Retinoic acid induced gene G protein; Retinoic acid-induced gene G protein; RIG-G; RIGG; CIG-49; GARG-49
Cat.#:IFIT3-14069HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IFIT3, GST-tagged
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Cat.#:IFIT3-94HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IFIT3, His-tagged
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Cat.#:IFIT3-5285HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human IFIT3 293 Cell Lysate
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Cat.#:IFIT3-5286HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human IFIT3 293 Cell Lysate
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Involved Pathway

IFIT3 involved in several pathways and played different roles in them. We selected most pathways IFIT3 participated on our site, such as Cytokine Signaling in Immune system, Immune System, Interferon Signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with IFIT3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cytokine Signaling in Immune system
TNFSF13B; TNFRSF13C; FGF18B; EDAR; FRS2B; PTPRA; IL1RN; IFI35; PRLRB; DUSP9
Immune System
PANX1B; CLEC5A; ABI1; LILRB1; SH2D1B; UFL1; IGHM; LY86; ASB6; LRRC41
Interferon Signaling
TRIM22; TRIM46; ADAR; EIF4G2; TRIM2; XAF1; TRIM45; IFI35; IFIT12; MX2
Interferon alpha/beta signaling
SAMHD1; OASL; IRF2; ISG20; IFITM3; IRF9; BST2; IRF6; IFITM2; IFIT3

Protein Function

IFIT3 has several biochemical functions, for example, RNA binding, identical protein binding, molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by IFIT3 itself. We selected most functions IFIT3 had, and list some proteins which have the same functions with IFIT3. You can find most of the proteins on our site.
Function
Related Protein
Function RNA binding
Related Protein RNMTL1A; EIF4H; HNRPKL; RBM12B2; DPPA5A; TLR13; APOBEC3F; QKIA; RPL9; HNRNPUL1
Function identical protein binding
Related Protein ETNPPL; ATXN3; SERPINB1A; TRIP13; ZNF3; COL1A2; CLDN23; GLUL; VPS4B; CLDN11
Function molecular_function
Related Protein WFDC6A; DNALC1; NAT14; MARVELD2B; MRGPRA2A; PIGY; MAP9; TSPAN35; TMEM56B; GM4179
Function protein binding
Related Protein DUSP21; USP18; RRAGD; TUFM; GUCY1B3; LPP; MEX3C; HSD17B14; FAM118B; USP25

IFIT3 Related Articles

Schmeisser, H; Mejido, J; et al. Identification of Alpha Interferon-Induced Genes Associated with Antiviral Activity in Daudi Cells and Characterization of IFIT3 as a Novel Antiviral Gene. JOURNAL OF VIROLOGY 84:10671-10680(2010).
Serrano-Fernandez, P; Moller, S; et al. Time course transcriptomics of IFNB1b drug therapy in multiple sclerosis. AUTOIMMUNITY 43:172-178(2010).