imp4
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  • Official Full Name
  • IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)
  • Background
  • IMP4 forms a ternary complex with IMP3 (MIM 612980) and MPP10 (MPHOSPHO10; MIM 605503) that interacts with U3 small;nucleolar RNA (snoRNA), which is required for the early cleavage steps in pre-rRNA processing (Granneman et al., 2003;(PubMed 12655004)).
  • Synonyms
  • IMP4; IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast); U3 small nucleolar ribonucleoprotein protein IMP4; BXDC4; MGC19606; D1Wsu40e; U3 snoRNP protein 4 homolog; U3 snoRNP protein IMP4; Brix domain containing protein 4; Brix domain-containing protein 4; IMP4_HUMAN; LRRGT00017
Cat.#:IMP4-5146HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human IMP4 Protein, GST-tagged
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Cat.#:IMP4-104HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IMP4, His-tagged
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Cat.#:IMP4-8193MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse IMP4 Protein
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Cat.#:IMP4-3055RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat IMP4 Protein
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Cat.#:IMP4-2263RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey IMP4 Protein, His-tagged
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Cat.#:IMP4-5087CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken IMP4
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Cat.#:IMP4-819ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish IMP4
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Cat.#:IMP4-5215HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human IMP4 293 Cell Lysate
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Involved Pathway

IMP4 involved in several pathways and played different roles in them. We selected most pathways IMP4 participated on our site, such as Ribosome biogenesis in eukaryotes, which may be useful for your reference. Also, other proteins which involved in the same pathway with IMP4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Ribosome biogenesis in eukaryotes
POP1; ACK2; DROSHA; RPP38; XPO1; WDR3; GNL3; RNASEN; UTP14A; RPP40

Protein Function

IMP4 has several biochemical functions, for example, protein binding, rRNA primary transcript binding, snoRNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IMP4 itself. We selected most functions IMP4 had, and list some proteins which have the same functions with IMP4. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein DAB1; IL12A; RELA; HACE1; DIAPH1; NHP2; VRK1; ABCD3; CTSD; RBM44
Function rRNA primary transcript binding
Related Protein PTRF; RPF1; NCL; IMP4
Function snoRNA binding
Related Protein NUDT7; HEATR1; DDX21; IMP3; UTP6; NHP2; NUDT16; NOP10; PWP2H; UTP15

Interacting Protein

IMP4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IMP4 here. Most of them are supplied by our site. Hope this information will be useful for your research of IMP4.
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IMP4 Related Articles

Granneman, S; Gallagher, JEG; et al. The human Imp3 and Imp4 proteins form a ternary complex with hMpp10, which only interacts with the U3 snoRNA in 60-80S ribonucleoprotein complexes. NUCLEIC ACIDS RESEARCH 31:1877-1887(2003).