inpp5f
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  • Official Full Name
  • inositol polyphosphate-5-phosphatase F
  • Background
  • The protein encoded by this gene is an inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase and contains a Sac domain. The activity of this protein is specific for phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
  • Synonyms
  • INPP5F; inositol polyphosphate-5-phosphatase F; phosphatidylinositide phosphatase SAC2; hSac2; KIAA0966; SAC2; cI-27; Inositol polyphosphate 5 phosphatase F; MSTP007; MSTP047; Sac domain containing inositol phosphatase 2; Sac domain-containing phosphoinositide 5-phosphatase 2; Sac domain-containing inositol phosphatase 2; MSTPO47
Cat.#:INPP5F-2398HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human INPP5F Protein, MYC/DDK-tagged
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Cat.#:INPP5F-6735ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish INPP5F
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Cat.#:INPP5F-863HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human INPP5F cell lysate
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Involved Pathway

INPP5F involved in several pathways and played different roles in them. We selected most pathways INPP5F participated on our site, such as 3-phosphoinositide degradation, D-myo-inositol (1,4,5)-trisphosphate degradation, superpathway of D-myo-inositol (1,4,5)-trisphosphate metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with INPP5F were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
3-phosphoinositide degradation
INPP5F; PTPMT1
D-myo-inositol (1,4,5)-trisphosphate degradation
INPP5F
superpathway of D-myo-inositol (1,4,5)-trisphosphate metabolism
INPP5F

Protein Function

INPP5F has several biochemical functions, for example, phosphoric ester hydrolase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by INPP5F itself. We selected most functions INPP5F had, and list some proteins which have the same functions with INPP5F. You can find most of the proteins on our site.
Function
Related Protein
Function phosphoric ester hydrolase activity
Related Protein INPP5F; TMPPE; EXO5; SYNJ1; ZRANB3; REXO4; SACM1LA; MEIOB; RAG1; RNASEKA

Interacting Protein

INPP5F has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with INPP5F here. Most of them are supplied by our site. Hope this information will be useful for your research of INPP5F.
YWHAB

INPP5F Related Articles

Montjean, R; Aoidi, R; et al. OCRL-mutated fibroblasts from patients with Dent-2 disease exhibit INPP5B-independent phenotypic variability relatively to Lowe syndrome cells. HUMAN MOLECULAR GENETICS 24:994-1006(2015).
Kim, HS; Li, AG; et al. Inositol Polyphosphate-5-Phosphatase F (INPP5F) inhibits STAT3 activity and suppresses gliomas tumorigenicity. SCIENTIFIC REPORTS 4:-(2014).