LC3
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | LC3-518H | Recombinant Human LC3, His-tagged | E.coli | His | 1-125aa |
- Involved Pathway
- Protein Function
- Interacting Protein
LC3 involved in several pathways and played different roles in them. We selected most pathways LC3 participated on our site, such as Cellular responses to stress, Macroautophagy, Mitophagy, which may be useful for your reference. Also, other proteins which involved in the same pathway with LC3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cellular responses to stress | DPF1;RING1;BMI1A;RPS19BP1;ERF;SUZ12;HSBP1B;ASF1A;EGLN2 |
| Macroautophagy | UVRAG;WDR45;DYNLL2B;GABARAPL2;GABARAP;ATG9A;WIPI2;AMBRA1;WIPI1 |
| Mitophagy | TOMM20;TOMM20B;MFN1;TOMM22;MAP1LC3B;MFN2;TOMM40;MTERFD1;TOMM70A |
| Pink/Parkin Mediated Mitophagy | TOMM7;MTERFD1;TOMM40;TOMM20;TOMM20B;TOMM22;MFN1;MFN2;LC3 |
| Senescence and Autophagy | IFI16;SLC39A2;RB1CC1;GABARAP;UVRAG;MAP1LC3B;GABARAPL2;IL24;SLC39A1 |
LC3 has several biochemical functions, for example, microtubule binding, phosphatidylethanolamine binding, phospholipid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LC3 itself. We selected most functions LC3 had, and list some proteins which have the same functions with LC3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| microtubule binding | CAMSAP1A;CAMSAP1B;JAKMIP2;PAFAH1B1;DPYSL2B;TRPV4;MTAP6;FAM154A;WDR81 |
| phosphatidylethanolamine binding | MFGE8;ANXA11;ESYT2;LC3;PEBP1;NF1;CD300A;PEMT |
| phospholipid binding | PICALMA;ANXA5;LPAR3;PSD4;SDPR;OSBPL1A;STAP1;SNCA;APOA1 |
| protein binding | ERCC2;CWC15;FAM32A;MASP2;DIS3;ACAA2;NAA35;IGF1;LBX1 |
| ubiquitin protein ligase binding | PER1;MAGEC2;PRKACA;UBE2K;TRIB2;UBE2G1B;UBE2KA;HERC2;UBE2W |
LC3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LC3 here. Most of them are supplied by our site. Hope this information will be useful for your research of LC3.
SQSTM1; NBR1; FUNDC1; Bnip3l
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