lc3
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  • Official Full Name
  • Synonyms
Cat.#:LC3-518HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human LC3, His-tagged
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Involved Pathway

LC3 involved in several pathways and played different roles in them. We selected most pathways LC3 participated on our site, such as Cellular responses to stress, Macroautophagy, Mitophagy, which may be useful for your reference. Also, other proteins which involved in the same pathway with LC3 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cellular responses to stress
MOV10; LC3; DNAJC7; DPF1; EGLN2; WDR45L; HIST1H1E; RPS19BP1; RBBP7; HSPA13
Macroautophagy
ULK1A; AMBRA1A; ATG9A; ATG4A; WDR45; ATG9B; WDR45L; ATG7; MAP1LC3C; DYNLL2A
Mitophagy
MAP1LC3B; TOMM7; TOMM70A; MFN1; TOMM6; MTERFD1; TOMM22; TOMM20; MFN2; LC3
Pink/Parkin Mediated Mitophagy
MAP1LC3B; TOMM70A; TOMM5; TOMM40; TOMM6; TOMM7; TOMM20B; MTERFD1; TOMM20; LC3
Senescence and Autophagy
COL10A1; GABARAPL2; ING1; FKBP8; SLC39A2; IGFBP5; MAP1LC3C; MAP1LC3B; CREG1; RB1CC1

Protein Function

LC3 has several biochemical functions, for example, microtubule binding, phosphatidylethanolamine binding, phospholipid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LC3 itself. We selected most functions LC3 had, and list some proteins which have the same functions with LC3. You can find most of the proteins on our site.
Function
Related Protein
Function microtubule binding
Related Protein ARHGEF2; KIF22; S100A8; FAM83D; CHP1; CAMSAP1A; EZR; APC; MAST2; UXT
Function phosphatidylethanolamine binding
Related Protein CD300A; PEBP1; PEMT; ESYT2; LC3; ANXA11; NF1; MFGE8
Function phospholipid binding
Related Protein APOB; APOE; PLA2G2A; ANXA5; PACSIN1A; SEC14L2; PREX1; RASAL1; AMPH; APOA1
Function protein binding
Related Protein RAB4A; LONRF3; MYO15; LPXN; DAPP1; C14orf93; SSU72; MAT2B; NBL1; AOC3
Function ubiquitin protein ligase binding
Related Protein CUL3B; RALB; UBE2L3; BCL10; TMEM189; NKD2; PRR5L; BLZF1; USP2; XBP1

Interacting Protein

LC3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LC3 here. Most of them are supplied by our site. Hope this information will be useful for your research of LC3.
SQSTM1; NBR1; FUNDC1; Bnip3l