lc3
Share
  • Official Full Name
  • Synonyms
Cat.#:LC3-518HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human LC3, His-tagged
+Inquiry

Involved Pathway

LC3 involved in several pathways and played different roles in them. We selected most pathways LC3 participated on our site, such as Cellular responses to stress, Macroautophagy, Mitophagy, which may be useful for your reference. Also, other proteins which involved in the same pathway with LC3 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cellular responses to stress
KDM6B; AGO3; HSPH1; NUPL2; HIST1H1C; TINF2; NUP35; ACD; PHC1; WDR45
Macroautophagy
ATG4A; GABARAPL2; ATG7; ATG9B; ULK1A; MAP1LC3B; WDR45L; UVRAG; AMBRA1A; WDR45
Mitophagy
TOMM70A; TOMM20; MFN1; TOMM22; TOMM20B; LC3; TOMM7; TOMM5; MTERFD1; TOMM6
Pink/Parkin Mediated Mitophagy
TOMM5; TOMM7; TOMM70A; MTERFD1; TOMM20B; MFN2; TOMM6; TOMM40; TOMM20; MFN1
Senescence and Autophagy
LC3; COL10A1; ATG7; ING1; IGFBP7; RSL1D1; ING2; MAP1LC3C; GABARAPL2; RB1CC1

Protein Function

LC3 has several biochemical functions, for example, microtubule binding, phosphatidylethanolamine binding, phospholipid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LC3 itself. We selected most functions LC3 had, and list some proteins which have the same functions with LC3. You can find most of the proteins on our site.
Function
Related Protein
Function microtubule binding
Related Protein MACF1; CCDC87; MAP1B; CKAP5; MAP4; CLIP1; PPP5C; PEX14; SGIP1; VAPB
Function phosphatidylethanolamine binding
Related Protein LC3; ESYT2; PEMT; CD300A; ANXA11; PEBP1; NF1; MFGE8
Function phospholipid binding
Related Protein SNCA; Defa4; ANXA5; TEC; APOA1; F10; AMPH; CPS1; SPTB; SGIP1
Function protein binding
Related Protein SPINK2; MYCBP2; MTMR7; PIBF1; PRKCB; ASCL4; FAM46B; P4HA2; NETO2; IGBP1
Function ubiquitin protein ligase binding
Related Protein EGR2; BAG4; BECN1; BCL2; DBT; SCAMP3; AURKA; ACTG1; AMBRA1; UBE2C

Interacting Protein

LC3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LC3 here. Most of them are supplied by our site. Hope this information will be useful for your research of LC3.
SQSTM1; NBR1; FUNDC1; Bnip3l