lc3
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  • Official Full Name
  • Synonyms
Cat.#:LC3-518HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human LC3, His-tagged
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Involved Pathway

LC3 involved in several pathways and played different roles in them. We selected most pathways LC3 participated on our site, such as Cellular responses to stress, Macroautophagy, Mitophagy, which may be useful for your reference. Also, other proteins which involved in the same pathway with LC3 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cellular responses to stress
CDK6; KAT5; ATG9B; SCMH1; C11orf73; CDKN2D; UVRAG; RRAGA; ST13; TXN
Macroautophagy
LC3; WDR45L; ULK1A; WIPI1; ATG101; ATG4A; ATG7; GABARAP; WDR45; MAP1LC3B
Mitophagy
TOMM20B; MTERFD1; TOMM5; LC3; TOMM22; MFN1; TOMM70A; MAP1LC3B; TOMM40; TOMM20
Pink/Parkin Mediated Mitophagy
TOMM7; MFN2; TOMM40; MTERFD1; TOMM5; TOMM6; LC3; TOMM20; TOMM70A; MAP1LC3B
Senescence and Autophagy
IGFBP7; RB1CC1; ATG7; SLC39A1; CREG1; MAP1LC3B; ING1; ING2; GABARAPL2; GABARAP

Protein Function

LC3 has several biochemical functions, for example, microtubule binding, phosphatidylethanolamine binding, phospholipid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LC3 itself. We selected most functions LC3 had, and list some proteins which have the same functions with LC3. You can find most of the proteins on our site.
Function
Related Protein
Function microtubule binding
Related Protein CHD4A; MAP4; MTAP7D3; PSRC1; SYBU; WDR81; GAS2L3; KIAA1128; DCX; MTAP6
Function phosphatidylethanolamine binding
Related Protein CD300A; ESYT2; PEBP1; MFGE8; NF1; ANXA11; LC3; PEMT
Function phospholipid binding
Related Protein PICALMA; BPIFC; SPTB; Defa4; PTAFR; NBEA; APOEA; DGKA; SHC1; SEC14L2
Function protein binding
Related Protein EFTUD2; CINP; USP42; PHIP; SMO; THOC4; EP300; RAB4A; LUC7L2; TBC1D7
Function ubiquitin protein ligase binding
Related Protein HSPA1A; TRP53; PRKAR1A; KCNQ3; TUBB; CDC34A; UBE2S; PIAS2; KDM4A; MFN2

Interacting Protein

LC3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LC3 here. Most of them are supplied by our site. Hope this information will be useful for your research of LC3.
SQSTM1; NBR1; FUNDC1; Bnip3l