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NDOR1

Official Full Name

NADPH dependent diflavin oxidoreductase 1
Overview

This gene encodes an NADPH-dependent diflavin reductase that contains both flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) binding domains. The encoded protein is an enzyme that catalyzes the transfers electrons from NADPH through FAD and FMN cofactors to potential redox partners. Alternative splicing results in multiple transcript variants.
Synonyms

NDOR1; NADPH dependent diflavin oxidoreductase 1; NADPH-dependent diflavin oxidoreductase 1; bA350O14.9; NADPH dependent FMN and FAD containing oxidoreductase; NR1; MGC138148; NADPH-dependent FMN and FAD-containing oxidoreductase; NDOR 1; NDOR1_HUMAN; Novel reductase 1; NR 1; OTTHUMP00000064742; RP11 350O14.11; OTTHUMP00000022695; OTTHUMP00000162579; NADPH-dependent FMN and FAD containing oxidoreductase; NADPH-dependent FMN and FAD-containing oxidoreduc;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Zebrafish

Source

E.coli
HEK293
HEK293T
Mammalian Cell

Tag

GST
His
His (Fc)
Avi
Myc
DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	NDOR1-1220H	Recombinant Human NDOR1, GST-tagged	E.coli	GST	C-term-350aa	$319 / 25ug
Human	NDOR1-3933HCL	Recombinant Human NDOR1 293 Cell Lysate	HEK293	N/A		Inquiry
Human	NDOR1-1856H	Recombinant Human NDOR1 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry
Mouse	NDOR1-10501M	Recombinant Mouse NDOR1 Protein	Mammalian Cell	His		Inquiry
Mouse	NDOR1-5956M-B	Recombinant Mouse NDOR1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	Ndor1-4323M	Recombinant Mouse Ndor1 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Mouse	NDOR1-5956M	Recombinant Mouse NDOR1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Zebrafish	NDOR1-10919Z	Recombinant Zebrafish NDOR1	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

NDOR1 involved in several pathways and played different roles in them. We selected most pathways NDOR1 participated on our site, such as Cytosolic iron-sulfur cluster assembly, Metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with NDOR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Cytosolic iron-sulfur cluster assembly	MMS19;CIAPIN1;NUBP2;NUBP1;FAM96B;CIAO1;NDOR1
Metabolism	CYP3A5;MED9;BCHE;GLYATL2;NDUFAF7;ADAL;CEPT1A;CYP2K8;CYP4F11

NDOR1 has several biochemical functions, for example, FMN binding, NADP binding, NADPH-hemoprotein reductase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NDOR1 itself. We selected most functions NDOR1 had, and list some proteins which have the same functions with NDOR1. You can find most of the proteins on our site.

Function	Related Protein
FMN binding	PNPO;NDOR1;POR;NOS2A;NOS3;DHODH;NOS1;NOS2;TYW1
NADP binding	NNT;NOS3;FMO3;HMGCRB;HMGCRA;NOS1;MIOX;ME1;DPYD
NADPH-hemoprotein reductase activity	NDOR1;NOS3;MTRR;NOS1;NOS2B;POR;NOS2;CYP2J6;NOS2A
flavin adenine dinucleotide binding	MTHFR;ACAD9;NDOR1;PPOX;NOS3;SQLEA;GSR;FOXRED2;MTO1
iron ion binding	CYP4F11;HBB-BH1;XDH;CYP2K17;OGFOD2;IRGM1;CYP2S1;CYP2A12;CYP4V2
oxidoreductase activity	ADOB;DHRS13;JMJD5;PDPR;LEPREL1;ETFA;CHML;SCCPDHB;AKR1C6
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	CYP11B1;MTRR;CYP11A1;CYP4F11;MICAL2;CYP4F2;CYP11B2;POR;COQ6
protein binding	MIER1;WNT3;PRNP;MYLIP;SLC9A1;NSUN4;SULT2A1;COL23A1;OPRK1

NDOR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NDOR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NDOR1.

TCF4; MTUS2; EFHC2; CIAPIN1; TCHP