OPN5
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Official Full Name
opsin 5
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Overview
Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. This opsin gene is expressed in the eye, brain, testes, and spinal cord. This gene belongs to the seven-exon subfamily of mammalian opsin genes that includes peropsin (RRH) and retinal G protein coupled receptor (RGR). Like these other seven-exon opsin genes, this family member may encode a protein with photoisomerase activity. Alternative splicing results in multiple transcript variants. -
Synonyms
OPN5; opsin 5; TMEM13, transmembrane protein 13; opsin-5; dJ402H5.1; neuropsin; Gpr136; G protein-coupled receptor 136; G-protein coupled receptor PGR12; HGNC:21318; PGR12; TMEM13; Transmembrane protein 13; G-protein coupled receptor 136;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Assay Kits
- Chicken
- Homo sapiens (Human)
- Human
- Mouse
- Mus musculus (Mouse)
- Zebrafish
- E.coli
- E.coli expression system
- HEK293
- Mammalian Cell
- His
- His (Fc)
- Avi
- N/A
- N
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Human | OPN5-919H | Recombinant Human OPN5 | Mammalian Cell | His | ||
Human | OPN5-2531H | Recombinant Human OPN5 Protein, His-tagged | E.coli | N-His | Met1-Thr181 | |
Human | OPN5-3733H-B | Recombinant Human OPN5 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Human | OPN5-3733H | Recombinant Human OPN5 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Mouse | OPN5-12172M | Recombinant Mouse OPN5 Protein | Mammalian Cell | His | ||
Mouse | OPN5-6400M | Recombinant Mouse OPN5 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Mouse | OPN5-6400M-B | Recombinant Mouse OPN5 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Homo sapiens (Human) | RFL22543HF | Recombinant Full Length Human Opsin-5(Opn5) Protein, His-Tagged | E.coli expression system | His | Full Length (1-354) | |
Mus musculus (Mouse) | RFL35382MF | Recombinant Full Length Mouse Opsin-5(Opn5) Protein, His-Tagged | E.coli expression system | His | Full Length (1-377) | |
Zebrafish | OPN5-7908Z | Recombinant Zebrafish OPN5 | Mammalian Cell | His | ||
Chicken | OPN5-3861C | Recombinant Chicken OPN5 | Mammalian Cell | His | ||
Kit-1449 | OPN5 CHO-K1 β-Arrestin Orphan GPCR Assay Kit | N/A |
- Involved Pathway
- Protein Function
- Interacting Protein
OPN5 involved in several pathways and played different roles in them. We selected most pathways OPN5 participated on our site, such as Class A/1 (Rhodopsin-like receptors), G alpha (i) signalling events, GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with OPN5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
Class A/1 (Rhodopsin-like receptors) | CNR2;EDN1;OPN4.1;XK;RGR;TAC3;AGTR1;CCL19A.2;UTS2 |
G alpha (i) signalling events | RGS10;SSTR5;ADRA2C;OPN1LW;CCR9;CXCR7B;SOUL4;NMS;NPB |
GPCR downstream signaling | NPS;CCR9;OR56A1;CASR;PTH;CCL27;ARHGEF17;CNR2;DCLRE1B |
GPCR ligand binding | CRHB;CHRM1;GPR37B;GPR18;GPR55;OXGR1;GPR31;OXER1;HCAR1-2 |
Opsins | OPN4;RGR;OPN4A;RGS1;OPN1LW2;OPN1LW1;OPN4.1;OPN1SW1;OPN4B |
Signal Transduction | CD97;GMIP;GPR31B;PTPRUB;RLBP1A;ABI1B;CDC42EP2;USP2;RSPO2 |
Signaling by GPCR | CCL19A.2;UTS2D;OPN5;PRKCHB;CRHB;PTHLHA;GPRC6A;RXFP2B;OXER1 |
OPN5 has several biochemical functions, for example, 11-cis retinal binding, G-protein coupled receptor activity, photoreceptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by OPN5 itself. We selected most functions OPN5 had, and list some proteins which have the same functions with OPN5. You can find most of the proteins on our site.
Function | Related Protein |
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11-cis retinal binding | RLBP1;OPN5;OPN4 |
G-protein coupled receptor activity | OLFCD2;OLFR480;AGTR1B;OLFCS1;GPR20;LPAR5;TAS2R123;LPHN1;OR5V1 |
photoreceptor activity | RHO;VALOPA;RGS1;TMTOPS3A;OPN1SW2;OPN1MW2;EXORH;OPN4.1;GRK7A |
OPN5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with OPN5 here. Most of them are supplied by our site. Hope this information will be useful for your research of OPN5.
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