tmed2
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  • Official Full Name
  • transmembrane emp24 domain trafficking protein 2
  • Background
  • Transmembrane emp24 domain-containing protein 2 is a protein that in humans is encoded by the TMED2 gene.
  • Synonyms
  • TMED2; transmembrane emp24 domain trafficking protein 2; transmembrane emp24 domain-containing protein 2; P24A; RNP24; p24beta1; membrane protein p24A; p24 family protein beta-1; coated vesicle membrane protein; p24; FLJ21323
Cat.#:TMED2-3271HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TMED2, GST-tagged
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Cat.#:TMED2-6099RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat TMED2 Protein
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Cat.#:TMED2-1029CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus TMED2 Protein, His-tagged
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Cat.#:TMED2-1335CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken TMED2
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Cat.#:TMED2-9953ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish TMED2
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Cat.#:TMED2-1025HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human TMED2 293 Cell Lysate
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Involved Pathway

TMED2 involved in several pathways and played different roles in them. We selected most pathways TMED2 participated on our site, such as Asparagine N-linked glycosylation, COPII (Coat Protein 2) Mediated Vesicle Transport, Cargo concentration in the ER, which may be useful for your reference. Also, other proteins which involved in the same pathway with TMED2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Asparagine N-linked glycosylation
NEU4; MPDU1A; ALG2; TMED10; USO1; MAN1A2; LMAN2; GORASP1; GNE; ANKRD28
COPII (Coat Protein 2) Mediated Vesicle Transport
NAPB; TRAPPC6BL; TRAPPC2; BET1; AREG; SERPINA1L; SEC16B; TRAPPC1; SCFD1; PPP6C
Cargo concentration in the ER
SEC23A; CNIH; MCFD2; CTSC; LMAN2; MIA3; CNIH3; SEC24A; TMED10; CTSZ
ER to Golgi Anterograde Transport
TMED2; SEC23IP; NAPG; TRAPPC6BL; NAPB; TRAPPC5; TMED10; CNIH2; BET1; TRAPPC6A
Membrane Trafficking
MIA3; TRAPPC6A; CNIH3; AP4B1; NAPG; RALAB; TMED2; CPD; TRAPPC3; NSFA
Metabolism of proteins
PAPPA2; PIGK; ARSH; SPON1A; YY2; ALG2; TOMM20; ACE; NSFA; ASNA1
Post-translational protein modification
NAPAB; ST8SIA3; KCNA6; MUC5AC; MPDU1A; DPH5; MAN1B1; SCMH1; ADAMTS4; TRAPPC2L
Pre-NOTCH Expression and Processing
TMED2; RAB6A

Protein Function

TMED2 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TMED2 itself. We selected most functions TMED2 had, and list some proteins which have the same functions with TMED2. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein INCA1; MMP15; TMEM218; FAM124B; E4F1; CBL; AMY1B; DOCK10; FAM154A; NUDC

Interacting Protein

TMED2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TMED2 here. Most of them are supplied by our site. Hope this information will be useful for your research of TMED2.
TMED10; F2RL1; CD59; SURF4

TMED2 Related Articles

Sakakibara, M; Uenoyama, Y; et al. Microarray Analysis of Perinatal-Estrogen-Induced Changes in Gene Expression Related to Brain Sexual Differentiation in Mice. PLOS ONE 8:-(2013).
Hou, WY; Sarikaya, D; et al. IS TMED2 ESSENTIAL IN THE CHORION FOR NORMAL INTERACTION BETWEEN THE ALLANTOIS AND THE CHORION IN MICE?. PLACENTA 34:A84-A84(2013).