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UFL1

  • Official Full Name

    UFM1-specific ligase 1

  • Synonyms

    UFL1; UFM1-specific ligase 1; KIAA0776; E3 UFM1-protein ligase 1; Maxer; NLBP; novel LZAP binding protein; RCAD; Regulator of CDK5RAP3 and DDRGK1; LZAP-binding protein; novel LZAP-binding protein; RP3-393D12.1;

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • HEK293
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human UFL1-4969HCL Recombinant Human KIAA0776 293 Cell Lysate HEK293 N/A
Mouse UFL1-17795M Recombinant Mouse UFL1 Protein Mammalian Cell His
Mouse UFL1-9877M-B Recombinant Mouse UFL1 Protein Pre-coupled Magnetic Beads HEK293
Mouse UFL1-9877M Recombinant Mouse UFL1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat UFL1-6426R Recombinant Rat UFL1 Protein Mammalian Cell His
Rat UFL1-6082R Recombinant Rat UFL1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat UFL1-6082R-B Recombinant Rat UFL1 Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey UFL1-1077C Recombinant Cynomolgus UFL1 Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey UFL1-820C Recombinant Cynomolgus Monkey UFL1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus Monkey UFL1-820C-B Recombinant Cynomolgus Monkey UFL1 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque UFL1-5093R Recombinant Rhesus monkey UFL1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque UFL1-4906R Recombinant Rhesus Macaque UFL1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque UFL1-4906R-B Recombinant Rhesus Macaque UFL1 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish UFL1-10884Z Recombinant Zebrafish UFL1 Mammalian Cell His
Chicken UFL1-3743C Recombinant Chicken UFL1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • UFL1 Related Articles

UFL1 involved in several pathways and played different roles in them. We selected most pathways UFL1 participated on our site, such as Adaptive Immune System, Antigen processing: Ubiquitination &amp, Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with UFL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Adaptive Immune SystemPDPK1A;EGF;RASGRP2;LILRB5;SIGLEC8;IGLC2;CYBB;TPP2;RNF6
Antigen processing: Ubiquitination &ampATG7;UBE2E3;RNF111;SPSB2;RNF34;SPSB1;FBXO44;RNF41;ASB14
Proteasome degradationNPEPPS;KLHL21;ASB8;RNF138;ASB11;RNF111;TRIM41;ASB17;TRIM50
Class I MHC mediated antigen processing &ampASB14;CYBA;TRIM69;KLHL21;CD207;FBXO17;KLHL20;SPSB4;RNF6
presentationUBE2V2;ASB4;TRIM41;UBE2F;SPSB1;FBXO3;STUB1;RNF220;ASB3
Immune SystemOSCAR;CLEC4D;CD300LD;SOCS3A;KPNA4;CSH1;TXNIPB;B2ML;CD200R1

UFL1 has several biochemical functions, for example, UFM1 transferase activity, ligase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by UFL1 itself. We selected most functions UFL1 had, and list some proteins which have the same functions with UFL1. You can find most of the proteins on our site.

Function Related Protein
UFM1 transferase activityUFL1;UFC1
ligase activityRNF31;RNF114;RNF125;PIAS3;HECW2;RANBP2;RNF220;UBE2I;SMURF1
protein bindingRAB35;JAKMIP2;GALNT2;TRMT61B;SNRPN;MYOZ2;HNRPLL;SSH1;TTF2

UFL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UFL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of UFL1.

PTP4A3; CASP4; CDK5RAP3; GSTK1; PHLDA3; UBE2D1; UBE2E1; UBE2D3; UBE2D2; rpoB; UBE2E3; UBE2W; UBE2D4; ssrna_ug; P

Zhang, YH; Zhang, MS; et al. Transcriptional Regulation of the Ufm1 Conjugation System in Response to Disturbance of the Endoplasmic Reticulum Homeostasis and Inhibition of Vesicle Trafficking. PLOS ONE 7:-(2012).
Tatsumi, K; Sou, YS; et al. A Novel Type of E3 Ligase for the Ufm1 Conjugation System. JOURNAL OF BIOLOGICAL CHEMISTRY 285:5417-5427(2010).
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