ufl1
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  • Official Full Name
  • UFM1-specific ligase 1
  • Synonyms
  • UFL1; UFM1-specific ligase 1; KIAA0776; E3 UFM1-protein ligase 1; Maxer; NLBP; novel LZAP binding protein; RCAD; Regulator of CDK5RAP3 and DDRGK1; LZAP-binding protein; novel LZAP-binding protein; RP3-393D12.1
Cat.#:UFL1-17795MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse UFL1 Protein
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Cat.#:UFL1-6426RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat UFL1 Protein
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Cat.#:UFL1-1077CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus UFL1 Protein, His-tagged
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Cat.#:UFL1-5093RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey UFL1 Protein, His-tagged
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Cat.#:UFL1-3743CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken UFL1
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Cat.#:UFL1-10884ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish UFL1
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Cat.#:UFL1-4969HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human KIAA0776 293 Cell Lysate
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Involved Pathway

UFL1 involved in several pathways and played different roles in them. We selected most pathways UFL1 participated on our site, such as Adaptive Immune System, Antigen processing: Ubiquitination &, Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with UFL1 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Adaptive Immune System
RAP1GAP2; CTSB; GAN; UBE2F; PTBP3; HUWE1; KLRB1B; FGF18B; TREML1; LILRA1
Antigen processing: Ubiquitination &
ASB3; LRR1; ARIH2; ASB17; LRSAM1; RNF25; BLMH; TRIM63; UBE2V1; SPSB2
Proteasome degradation
TPP2; TRIM50; STUB1; RNF4; ASB18; GAN; ASB11; FBXO17; ASB9; IWS1
Class I MHC mediated antigen processing &
FBXO27; UBE2E3; ASB6; CMTM2A; ERAP2; ASB3; UBA5; SPSB4; ASB8; RNF19B
presentation
TRIM39; UBR1; RNF25; CTSL1; NPEPPS; SH3RF1; ASB13; ASB17; LTN1; KLHL20
Immune System
KIF15; TREML1; POLR3F; IL1RN; DZIP3; BTR02; DEFB4A; MYO1C; GZMM; CASPB

Protein Function

UFL1 has several biochemical functions, for example, UFM1 transferase activity, ligase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by UFL1 itself. We selected most functions UFL1 had, and list some proteins which have the same functions with UFL1. You can find most of the proteins on our site.
Function
Related Protein
Function UFM1 transferase activity
Related Protein UFL1; UFC1
Function ligase activity
Related Protein IRF2BP1; LRSAM1; RNF125; ACSL1; RNF114; RNF126; RNF213; RTCB; ITCHA; TRIP12
Function protein binding
Related Protein AMBP; VEGFAB; FAM195A; IGBP1; IL1RN; TUBGCP2; PRH1; SALL4; ESYT2; MAT2A

Interacting Protein

UFL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UFL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of UFL1.
PTP4A3; CASP4; CDK5RAP3; GSTK1; PHLDA3; UBE2D1; UBE2E1; UBE2D3; UBE2D2; rpoB; UBE2E3; UBE2W; UBE2D4; ssrna_ug; P

UFL1 Related Articles

Zhang, YH; Zhang, MS; et al. Transcriptional Regulation of the Ufm1 Conjugation System in Response to Disturbance of the Endoplasmic Reticulum Homeostasis and Inhibition of Vesicle Trafficking. PLOS ONE 7:-(2012).
Tatsumi, K; Sou, YS; et al. A Novel Type of E3 Ligase for the Ufm1 Conjugation System. JOURNAL OF BIOLOGICAL CHEMISTRY 285:5417-5427(2010).