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WASF3

Official Full Name

WAS protein family, member 3
Overview

This gene encodes a member of the Wiskott-Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all family members. The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function.
Synonyms

WASF3; WAS protein family, member 3; wiskott-Aldrich syndrome protein family member 3; KIAA0900; SCAR3; WAVE3; Protein WAVE-3; Protein WAVE3; Verprolin homology domain containing protein 3; Verprolin homology domain-containing protein 3; WASF3_HUMAN; WASP family protein member 3; Wiskott Aldrich syndrome protein family member 3; OTTHUMP00000018160; WASP family Verprolin-homologous protein 3; Brush-1;

Type

Cell & Tissue Lysates
Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rhesus Macaque

Source

HEK293
Mammalian Cell

Tag

His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	WASF3-1919HCL	Recombinant Human WASF3 cell lysate		N/A	Inquiry
Mouse	WASF3-18428M	Recombinant Mouse WASF3 Protein	Mammalian Cell	His	Inquiry
Mouse	WASF3-10107M	Recombinant Mouse WASF3 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Mouse	WASF3-10107M-B	Recombinant Mouse WASF3 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Rhesus Macaque	WASF3-5184R	Recombinant Rhesus monkey WASF3 Protein, His-tagged	Mammalian Cell	His	Inquiry
Rhesus Macaque	WASF3-4997R	Recombinant Rhesus Macaque WASF3 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Rhesus Macaque	WASF3-4997R-B	Recombinant Rhesus Macaque WASF3 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry

Involved Pathway
Protein Function
Interacting Protein

WASF3 involved in several pathways and played different roles in them. We selected most pathways WASF3 participated on our site, such as Adherens junction, Choline metabolism in cancer, Fc gamma R-mediated phagocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with WASF3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Adherens junction	RAC1;CDC42L2;FER;TJP1;CTNND1;CTNNA2;BAIAP2A;ACTG1;ACP1
Choline metabolism in cancer	DGKB;PDGFB;PIP5K1B;HIF1A;SOS1;SP1;SLC22A1;SLC22A3;PIK3CA
Fc gamma R-mediated phagocytosis	PIK3CG;FCGR3A;LIMK1;WASF3;PIK3R3;INPPL1;MARCKSL1;SPHK2;WASF1
Fcgamma receptor (FCGR) dependent phagocytosis	DOCK1;ACTR2B;PPAPDC1A;MYO1C;ACTR3;IgG3;ARPC1A;WASF3;PLD4
Immune System	CD300LG;EDAR;UBE2U;KIF15;KIF3C;IFIT2;PRLRB;TRIM48;DEFB104A
Innate Immune System	LAT2;PELI3;WIPF2;PANX1A;CTSK;DEFB4B;IRF2;SIGIRR;NLRP4C
RHO GTPase Effectors	KTN1;PRC1B;RHPN2;ABI1;KLC3;CDCA8;WIPF2;RTKN;IQGAP3
RHO GTPases Activate WASPs and WAVEs	ABI2;WIPF2;WASF3;ABI1B;WIPF3;NCKIPSD;ABI1A

WASF3 has several biochemical functions, for example, actin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by WASF3 itself. We selected most functions WASF3 had, and list some proteins which have the same functions with WASF3. You can find most of the proteins on our site.

Function	Related Protein
actin binding	FMNL2;GC;NCALD;MTSS1L;INPPL1A;CCDC88A;WASF3;EPS8L2;ABLIM1A

WASF3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with WASF3 here. Most of them are supplied by our site. Hope this information will be useful for your research of WASF3.

EGFR; CAMK2D