wbp11
Share
  • Official Full Name
  • WW domain binding protein 11
  • Background
  • This gene encodes a nuclear protein, which colocalizes with mRNA splicing factors and intermediate filament-containing perinuclear networks. This protein has 95% amino acid sequence identity to the mouse Wbp11 protein. It contains two proline-rich regions that bind to the WW domain of Npw38, a nuclear protein, and thus this protein is also called Npw38-binding protein NpwBP. The Npw38-NpwBP complex may function as a component of an mRNA factory in the nucleus.
  • Synonyms
  • WBP11; WW domain binding protein 11; WW domain-binding protein 11; NPWBP; SIPP1; splicing factor; PQBP1 and PP1 interacting; DKFZp779M1063; MGC94547; Npw38 binding protein; Npw38 binding protein NpwBP; SH3 domain binding protein SNP70; SNP70; Splicing factor PQBP1 and PP1 interacting; WBP 11; Npw38-binding protein NpwBP; SH3 domain-binding protein SNP70; splicing factor, PQBP1 and PP1 interacting; splicing factor that interacts with PQBP-1 and PP1; WBP-11
Cat.#:WBP11-18432MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse WBP11 Protein
+Inquiry
Cat.#:WBP11-6560RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat WBP11 Protein
+Inquiry
Cat.#:WBP11-5186RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey WBP11 Protein, His-tagged
+Inquiry
Cat.#:WBP11-11680ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish WBP11
+Inquiry
Cat.#:WBP11-1920HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human WBP11 cell lysate
+Inquiry

Involved Pathway

WBP11 involved in several pathways and played different roles in them. We selected most pathways WBP11 participated on our site, such as Spliceosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with WBP11 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Spliceosome
RBM25; SRSF3; PPIE; BUD31; PHF5A; SNRNP40; PRPF4; SNRPA; HNRNPA3; PRPF6

Protein Function

WBP11 has several biochemical functions, for example, WW domain binding, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by WBP11 itself. We selected most functions WBP11 had, and list some proteins which have the same functions with WBP11. You can find most of the proteins on our site.
Function
Related Protein
Function WW domain binding
Related Protein CDC25C; NDFIP2; TNK2; ATCAY; WBP5; WBP1; TCEAL3; PMEPA1; TMEM128; TRAF4
Function poly(A) RNA binding
Related Protein RPP25L; CORO1A; NOL11; NOC2L; H2-Q10; APOBEC3B; EIF3C; CDKN2A; EXOSC8; MTERF
Function protein binding
Related Protein RPL28; LRP5; NAT8; CDCP1; SMG5; MED31; GLMN; MESDC1; CMTM2A; KAT8
Function protein phosphatase type 1 regulator activity
Related Protein UBXN2A; PPP1R7; PHACTR3B; PHACTR3; KCNS1; PPP1R15A; UBXN2B; PPP1R8; PHACTR4B; PHACTR1
Function single-stranded DNA binding
Related Protein MCM4; CNBPA; CTC1; LONP1; TSN; TSNAX; ERCC5; RAD51AP1; SSBP3; POLR2G

Interacting Protein

WBP11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with WBP11 here. Most of them are supplied by our site. Hope this information will be useful for your research of WBP11.
GRB2; PQBP1; q99ib8-pro_0000045603; FYN; TESC; TRAF4; PPP1CA