btd
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  • Official Full Name
  • biotinidase
  • Background
  • Biotinidase functions to recycle biotin in the body by cleaving biocytin (biotin-epsilon-lysine), a normal product of carboxylase degradation, resulting in regeneration of free biotin. Biotinidase has also been shown to have biotinyl-transferase activity. Defects in the biotinidase gene cause multiple carboxylase deficiency.
  • Synonyms
  • BTD; biotinidase; EC 3.5.1.12; Biotinase; BTD_HUMAN; OTTHUMP00000160300; OTTHUMP00000209134; OTTHUMP00000209135; OTTHUMP00000209138
Cat.#:BTD-1681HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human BTD protein, His-tagged
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Cat.#:BTD-355HTag:FC/His
Source (Host):HEK293Species:Human
Product nameRecombinant Human BTD, His tagged
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Cat.#:BTD-379HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human BTD Protein, GST-tagged
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Cat.#:BTD-46HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human BTD, His-tagged
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Cat.#:BTD-8392HTag:His
Source (Host):CHOSpecies:Human
Product nameRecombinant Human BTD, His-tagged
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Cat.#:BTD-8393HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human BTD, MYC/DDK-tagged
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Cat.#:BTD-2528MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse BTD Protein
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Cat.#:BTD-1028RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat BTD Protein
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Cat.#:BTD-4428CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken BTD
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Cat.#:BTD-4424ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish BTD
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Cat.#:BTD-8395HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human BTD 293 Cell Lysate
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Involved Pathway

BTD involved in several pathways and played different roles in them. We selected most pathways BTD participated on our site, such as Biotin metabolism, Metabolic pathways, Vitamin digestion and absorption, which may be useful for your reference. Also, other proteins which involved in the same pathway with BTD were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Biotin metabolism
BTD; OXSM; HLCS
Metabolic pathways
POLR2K; ASL2; EPHX2; HPSE2; CMPK1; QDPR; GALNT6; GUK1A; HSD3B6; DGAT2
Vitamin digestion and absorption
SLC19A3; SCARB1; APOA4; CUBN; FOLH1; MMACHC; ABCC1; LMBRD1; SLC5A6; GIF

Protein Function

BTD has several biochemical functions, for example, biotinidase activity, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds. Some of the functions are cooperated with other proteins, some of the functions could acted by BTD itself. We selected most functions BTD had, and list some proteins which have the same functions with BTD. You can find most of the proteins on our site.
Function
Related Protein
Function biotinidase activity
Related Protein BTD; SIRT4
Function hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
Related Protein NAAA; DPYSL5B; DPYSL3; BTD; DPYSL5; DPYSL2B; DPYSL5A; YDJC; DPYSL4; CRMP1

Interacting Protein

BTD has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BTD here. Most of them are supplied by our site. Hope this information will be useful for your research of BTD.
KIF21B; cona_canen; CCND1; CDCA5; SIKE1

BTD Related Articles

Winkens, T; Pachmann, K; et al. Circulating epithelial cells in patients with thyroid carcinoma Can they be identified in the blood?. NUKLEARMEDIZIN-NUCLEAR MEDICINE 52:7-13(2013).
Kang, UB; Ahn, Y; et al. Differential profiling of breast cancer plasma proteome by isotope-coded affinity tagging method reveals biotinidase as a breast cancer biomarker. BMC CANCER 10:-(2010).