btg1
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  • Official Full Name
  • B-cell translocation gene 1, anti-proliferative
  • Background
  • This gene is a member of an anti-proliferative gene family that regulates cell growth and differentiation. Expression of this gene is highest in the G0/G1 phases of the cell cycle and downregulated when cells progressed through G1. The encoded protein interacts with several nuclear receptors, and functions as a coactivator of cell differentiation. This locus has been shown to be involved in a t(8;12)(q24;q22) chromosomal translocation in a case of B-cell chronic lymphocytic leukemia.
  • Synonyms
  • BTG1; B-cell translocation gene 1, anti-proliferative; protein BTG1; B-cell translocation gene 1 protein
Cat.#:BTG1-067HTag:HIS
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human BTG1 Protein, HIS-tagged
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Cat.#:BTG1-10319HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human BTG1, GST-tagged
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Cat.#:BTG1-382HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human BTG1 Protein, GST-tagged
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Cat.#:BTG1-2531MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse BTG1 Protein
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Cat.#:BTG1-1029RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat BTG1 Protein
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Cat.#:BTG1-576RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey BTG1 Protein, His-tagged
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Cat.#:BTG1-6902CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken BTG1
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Cat.#:BTG1-10379ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish BTG1
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Cat.#:BTG1-8393HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human BTG1 293 Cell Lysate
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Involved Pathway

BTG1 involved in several pathways and played different roles in them. We selected most pathways BTG1 participated on our site, such as RNA degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with BTG1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
RNA degradation
PABPC1B; BTG4; DIS3L; PABPC1L2A; MPHOSPH6; DCP2; EDC4; LSM2; BTG3; PABPC3

Protein Function

BTG1 has several biochemical functions, for example, enzyme binding, kinase binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BTG1 itself. We selected most functions BTG1 had, and list some proteins which have the same functions with BTG1. You can find most of the proteins on our site.
Function
Related Protein
Function enzyme binding
Related Protein RPS19BP1; PTPLAD1; SLPI; PRKCD; THRB; ARRB2; BLZF1; KRT79; RXRA; TOP2B
Function kinase binding
Related Protein DLG4; BCL10; CEBPA; WWC1; TNFAIP3; PTPN22; CDC37; PIP5K1A; PFKL; RPS3
Function protein binding
Related Protein DLG1; CALR; CDC27; UBE2K; STX10; TBC1D10C; RABIF; ARMCX5-GPRASP2; ANKRD49; ATP6V1C1
Function transcription cofactor activity
Related Protein MED16; ZNF212; LPXN; MED1; TMF1; NFE2L1; MAP3K7; MED12; NMI; IRF3

Interacting Protein

BTG1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BTG1 here. Most of them are supplied by our site. Hope this information will be useful for your research of BTG1.
CNOT8; CNOT7; Cnot7; XRCC6; TUBA1A; RNF181