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CHSY1

Official Full Name

chondroitin sulfate synthase 1
Overview

CHSY1 synthesizes chondroitin sulfate, a glycosaminoglycan expressed on the surface of most cells and in extracellular matrices. Glycosaminoglycan chains are covalently linked to a wide range of core protein families and regulate many biologic processes, including cell proliferation and recognition, extracellular matrix deposition, and morphogenesis.
Synonyms

CHSY1; chondroitin sulfate synthase 1; Chondroitin glucuronyltransferase 1; Chondroitin synthase 1; CHSS1_HUMAN; ChSy-1; Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase 1; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 1; N-acetylgalactosaminyltransferase 1; OTTHUMP00000194839; N-acetylgalactosaminyltransferase II; chondroitin glucuronyltransferase II; CHSY; CSS1; TPBS;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Zebrafish

Source

E.coli
HEK293
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
N

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	CHSY1-11235H	Recombinant Human CHSY1, GST-tagged	E.coli	GST	449-802a.a.	$319 / 25ug
Human	CHSY1-1348H	Recombinant Human CHSY1 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Mouse	CHSY1-3458M	Recombinant Mouse CHSY1 Protein	Mammalian Cell	His		Inquiry
Mouse	CHSY1-1679M	Recombinant Mouse CHSY1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	Chsy1-784M	Recombinant Mouse Chsy1 Protein, His&GST-tagged	E.coli	N-His&GST	Leu601-Ala800	Inquiry
Mouse	CHSY1-1679M-B	Recombinant Mouse CHSY1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	CHSY1-11954Z	Recombinant Zebrafish CHSY1	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

CHSY1 involved in several pathways and played different roles in them. We selected most pathways CHSY1 participated on our site, such as Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with CHSY1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	CSGALNACT1;B3GALT6;CHST3B;CHST3;CHST7;B4GALT7;CHSY1;UST;CHST15
Metabolic pathways	NNMT;HSD3B4;AGPHD1;CYP27A1;LPIN1;HSD17B6;ATP6V1F;SAT2B;PCK2

CHSY1 has several biochemical functions, for example, N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity, glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CHSY1 itself. We selected most functions CHSY1 had, and list some proteins which have the same functions with CHSY1. You can find most of the proteins on our site.

Function	Related Protein
N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity	CHPF;CHSY1;CHPF2;CHSY3
glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity	CSGALNACT1;CHPF;CHSY1;CHSY3
metal ion binding	KLF10;ERI1;NRXN3A;RPS27.2;KLF6;NRXN1B;ZNF526;MKRN4;ZFP580

CHSY1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHSY1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CHSY1.

dedA3; GOLT1B