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EFHC2

Official Full Name

EF-hand domain (C-terminal) containing 2
Overview

This gene encodes a protein which contains three DM10 domains and three calcium-binding EF-hand motifs. A related protein is encoded by a gene on chromosome 6. It has been suggested that both proteins are involved in the development of epilepsy (PMID: 15258581, 16112844) and that this gene may be associated with fear recognition in individuals with Turner syndrome.
Synonyms

EFHC2; EF-hand domain (C-terminal) containing 2; EF-hand domain-containing family member C2; FLJ22843; dJ1158H2.1; DKFZp686G08235; EF hand domain (C terminal) containing 2; EF hand domain containing family member C2; FLJ22601;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	EFHC2-3092H	Recombinant Human EFHC2 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	EFHC2-535HCL	Recombinant Human EFHC2 cell lysate		N/A		Inquiry
Human	EFHC2-4212HF	Recombinant Full Length Human EFHC2 Protein, GST-tagged	In Vitro Cell Free System	GST	749 amino acids	Inquiry
Zebrafish	EFHC2-3520Z	Recombinant Zebrafish EFHC2	Mammalian Cell	His		Inquiry
Chicken	EFHC2-3298C	Recombinant Chicken EFHC2	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
EFHC2 Related Articles

EFHC2 involved in several pathways and played different roles in them. We selected most pathways EFHC2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with EFHC2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

EFHC2 has several biochemical functions, for example, calcium ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EFHC2 itself. We selected most functions EFHC2 had, and list some proteins which have the same functions with EFHC2. You can find most of the proteins on our site.

Function	Related Protein
calcium ion binding	PLA2G2E;RCN1;SULF2;CDH10A;CDH19;PCDHB14;GM5077;EHD4;S100V2
protein binding	TBL1XR1;HHLA3;ERRFI1;MT2A;CBX4;NCL;SUB1;LSM2;C1orf187

EFHC2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EFHC2 here. Most of them are supplied by our site. Hope this information will be useful for your research of EFHC2.

TRIM42; a8k932_human; COPE; NCK2; PLOD3; STK16; CLIC3

Castagne, R; Zeller, T; et al. Influence of sex and genetic variability on expression of X-linked genes in human monocytes. GENOMICS 98:320-326(2011).

Bajo, IM; Bodi, LRR; et al. Study protocol of genetic mental retardation. SALUD I CIENCIA 17:449-452(2010).