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KCNK10

  • Official Full Name

    potassium channel, subfamily K, member 10

  • Overview

    The protein encoded by this gene belongs to the family of potassium channel proteins containing two pore-forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations, and is stimulated strongly by arachidonic acid and to a lesser degree by membrane stretching, intracellular acidification, and general anaesthetics. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
  • Synonyms

    KCNK10; potassium channel, subfamily K, member 10; potassium channel subfamily K member 10; K2p10.1; TREK 2; TREK2; Outward rectifying potassium channel protein TREK 2; Potassium channel TREK 2; TREK 2 K; TWIK related K+ channel 2; OTTHUMP00000244287; OTTHUMP00000244288; OTTHUMP00000244289; potassium channel TREK-2; TWIK-related K+ channel 2; TREK-2 K(+) channel subunit; 2P domain potassium channel TREK2; outward rectifying potassium channel protein; TREK-2;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Homo sapiens (Human)
  • Human
  • Rat
  • Rattus norvegicus (Rat)
  • Rhesus Macaque
  • E.coli
  • E.coli expression system
  • HEK293
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human KCNK10-261H Recombinant Human KCNK10, His-tagged E.coli His 325-543aa
Human KCNK10-5038HCL Recombinant Human KCNK10 293 Cell Lysate HEK293 N/A
Human KCNK10-5039HCL Recombinant Human KCNK10 293 Cell Lysate HEK293 N/A
Human KCNK10-5040HCL Recombinant Human KCNK10 293 Cell Lysate HEK293 N/A
Human KCNK10-646HCL Recombinant Human KCNK10 Lysate HEK293 Myc/DDK
Rat KCNK10-3207R Recombinant Rat KCNK10 Protein Mammalian Cell His
Rat KCNK10-2863R Recombinant Rat KCNK10 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat KCNK10-2863R-B Recombinant Rat KCNK10 Protein Pre-coupled Magnetic Beads HEK293
Homo sapiens (Human) RFL26893HF Recombinant Full Length Human Potassium Channel Subfamily K Member 10(Kcnk10) Protein, His-Tagged E.coli expression system His Full Length (1-538)
Rattus norvegicus (Rat) RFL7908RF Recombinant Full Length Rat Potassium Channel Subfamily K Member 10(Kcnk10) Protein, His-Tagged E.coli expression system His Full Length (1-538)
Rhesus Macaque KCNK10-2362R Recombinant Rhesus monkey KCNK10 Protein, His-tagged Mammalian Cell His
Rhesus Macaque KCNK10-2183R-B Recombinant Rhesus Macaque KCNK10 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque KCNK10-2183R Recombinant Rhesus Macaque KCNK10 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein

KCNK10 involved in several pathways and played different roles in them. We selected most pathways KCNK10 participated on our site, such as Gastric acid secretion, which may be useful for your reference. Also, other proteins which involved in the same pathway with KCNK10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Gastric acid secretionPRKACB;ATP1A2;ATP4B;KCNQ1;MYLK3;PRKCA;PRKCB;KCNK2;ITPR1

KCNK10 has several biochemical functions, for example, potassium channel activity, potassium ion leak channel activity, voltage-gated ion channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KCNK10 itself. We selected most functions KCNK10 had, and list some proteins which have the same functions with KCNK10. You can find most of the proteins on our site.

Function Related Protein
potassium channel activityKCNK9;KCNK16;KCNIP3;KCNK5B;KCNC3A;KCNC1A;KCNK1B;KCNK1;KCNK1A
potassium ion leak channel activityKCNK15;KCNK6;KCNK9;KCNK3;KCNK1;KCNK3A;KCNK2B;KCNK5A;KCNK7
voltage-gated ion channel activityCLIC2;TRPM5;TPCN1;CACNA1SB;CACNG2B;KCNS3B;KCNA6A;KCNJ1A.5;CLIC6

KCNK10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KCNK10 here. Most of them are supplied by our site. Hope this information will be useful for your research of KCNK10.

PPP1CA; Akap5

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