lect2
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  • Official Full Name
  • leukocyte cell-derived chemotaxin 2
  • Background
  • This gene encodes a secreted, 16 kDa protein that acts as a chemotactic factor to neutrophils and stimulates the growth of chondrocytes and osteoblasts. This protein has high sequence similarity to the chondromodulin repeat regions of the chicken myb-induced myeloid 1 protein. A polymorphism in this gene may be associated with rheumatoid arthritis.
  • Synonyms
  • LECT2; leukocyte cell-derived chemotaxin 2; leukocyte cell-derived chemotaxin-2; chm II; chm2; Chondromodulin II; hLECT2; LECT 2; Leukocyte cell derived chemotaxin 2; MGC126628; chondromodulin-II; OTTHUMP00000159422; OTTHUMP00000223349; OTTHUMP00000228311; chm-II
Cat.#:Lect2-264MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Lect2 Protein, His-tagged
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Cat.#:Lect2-265RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Lect2 Protein, His-tagged
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Cat.#:LECT2-9032HTag:GST
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human LECT2 protein, GST-tagged
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Cat.#:LECT2-9033HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human LECT2 protein, MYC/DDK-tagged
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Cat.#:LECT2-9034MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse LECT2 Protein
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Cat.#:LECT2-9035MTag:His/T7
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Lect2 protein, His/T7-tagged
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Cat.#:Lect2-9035RTag:His/T7
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Lect2 protein, His/T7-tagged
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Cat.#:LECT2-2494RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey LECT2 Protein, His-tagged
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Cat.#:LECT2-7027CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken LECT2
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Cat.#:LECT2-4779HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human LECT2 293 Cell Lysate
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Involved Pathway

LECT2 involved in several pathways and played different roles in them. We selected most pathways LECT2 participated on our site, such as C-MYB transcription factor network, which may be useful for your reference. Also, other proteins which involved in the same pathway with LECT2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
C-MYB transcription factor network
PRTN3; MYB; TOM1; CSF1R; MYF6; GATA1; MYC; ADA; SLC25A3; LECT2

Protein Function

LECT2 has several biochemical functions, for example, identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LECT2 itself. We selected most functions LECT2 had, and list some proteins which have the same functions with LECT2. You can find most of the proteins on our site.
Function
Related Protein
Function identical protein binding
Related Protein DYNLT1A; CLDN11; PARK7; DRD2; HTT; RELA; FAS; EGFR; TOPBP1; BRAF

LECT2 Related Articles

Paueksakon, P; Fogo, AB; et al. Leukocyte chemotactic factor 2 amyloidosis cannot be reliably diagnosed by immunohistochemical staining. HUMAN PATHOLOGY 45:1445-1450(2014).
Murphy, CL; Wang, SC; et al. Leukocyte Chemotactic Factor 2 (LECT2)-Associated Renal Amyloidosis: A Case Series. AMERICAN JOURNAL OF KIDNEY DISEASES 56:1100-1107(2010).