mcrs1
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  • Official Full Name
  • microspherule protein 1
  • Background
  • Microspherule protein 1 is a protein that in humans is encoded by the MCRS1 gene.
  • Synonyms
  • MCRS1; microspherule protein 1; ICP22BP; INO80 complex subunit Q; INO80Q; MCRS2; MSP58; P78; INO80 complex subunit J; 58 kDa microspherule protein; cell cycle-regulated factor p78; cell cycle-regulated factor (78 kDa)
Cat.#:MCRS1-4510HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human MCRS1 Protein, GST-tagged
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Cat.#:MCRS1-30186THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MCRS1, His-tagged
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Cat.#:MCRS1-12466ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish MCRS1
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Cat.#:MCRS1-4411HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human MCRS1 293 Cell Lysate
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Involved Pathway

MCRS1 involved in several pathways and played different roles in them. We selected most pathways MCRS1 participated on our site, such as Chromatin modifying enzymes, Chromatin organization, DNA Damage Recognition in GG-NER, which may be useful for your reference. Also, other proteins which involved in the same pathway with MCRS1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Chromatin modifying enzymes
SMARCB1A; NCOA2; MTA3; SMARCC2; MORF4L2; KDM7AB; KAT6B; SMYD3; SMARCA4; KDM5B
Chromatin organization
KDM1A; ING4; TADA1; MTA3; MCRS1; EP400; CARM1; SMARCD3; SMARCB1; KDM5BB
DNA Damage Recognition in GG-NER
COPS7A; COPS3; ACTR5; YY1A; YY1; COPS2; NFRKB; INO80B; PARP2; DDB2
DNA Repair
PPP4CB; UBE2V2; CHEK1; RAD9A; INO80E; USP45; INO80; KDM4B; EYA3; COPS4
Global Genome Nucleotide Excision Repair (GG-NER)
COPS7A; ACTR5; INO80C; COPS7B; COPS2; DDB2; YY1A; COPS8; ACTL6A; PARP2
HATs acetylate histones
ING3; MCRS1; ING5B; ACTL6A; RUVBL2; KANSL2; C20orf20; ATXN7; JADE1; KAT6B
Herpes simplex infection
SFRS9; Ccl12; TBPL1; TAB2; HLA-DRB5; NFKBIA; PVRL1; NXF3; MYD88; SRSF2A
Nucleotide Excision Repair
XPC; RFC4; INO80; GTF2H1; TFPT; RAD23AA; ERCC6; MNAT1; COPS4; ERCC1

Protein Function

MCRS1 has several biochemical functions, for example, contributes_to histone acetyltransferase activity (H4-K16 specific), contributes_to histone acetyltransferase activity (H4-K5 specific), contributes_to histone acetyltransferase activity (H4-K8 specific). Some of the functions are cooperated with other proteins, some of the functions could acted by MCRS1 itself. We selected most functions MCRS1 had, and list some proteins which have the same functions with MCRS1. You can find most of the proteins on our site.
Function
Related Protein
Function contributes_to histone acetyltransferase activity (H4-K16 specific)
Related Protein KAT8; HCFC1; KANSL2; OGT; MCRS1; KANSL3; KIAA1267; PHF20B
Function contributes_to histone acetyltransferase activity (H4-K5 specific)
Related Protein PHF20B; KANSL2; KIAA1267; OGT; KAT8; MCRS1; KANSL3; HCFC1
Function contributes_to histone acetyltransferase activity (H4-K8 specific)
Related Protein KANSL2; OGT; KAT8; KANSL3; PHF20B; HCFC1; MCRS1; KIAA1267
Function protein binding
Related Protein AQP5; SGIP1; CARTPT; DAPP1; MANBAL; NIPSNAP1; NRCAM; OTUB2; GSDMA2; NELL1
Function telomerase inhibitor activity
Related Protein POT1; PINX1; POT1A; MCRS1

Interacting Protein

MCRS1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MCRS1 here. Most of them are supplied by our site. Hope this information will be useful for your research of MCRS1.
CCDC53; DAXX; TRIM37; INO80E

MCRS1 Related Articles

Bader, AG; Schneider, ML; et al. TOJ3, a target of the v-jun transcription factor, encodes a protein with transforming activity related to human microspherule protein 1 (MCRS1). ONCOGENE 20:7524-7535(2001).