p2rx2
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  • Official Full Name
  • purinergic receptor P2X, ligand-gated ion channel, 2
  • Background
  • The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Aug 2013]
  • Synonyms
  • P2RX2; purinergic receptor P2X, ligand-gated ion channel, 2; P2X2; DFNA41; P2X purinoceptor 2; ATP receptor; P2X Receptor, subunit 2;
Cat.#:P2RX2-142HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human P2RX2 Protein, MYC/DDK-tagged
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Cat.#:P2RX2-143HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human P2RX2 Protein, MYC/DDK-tagged
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Cat.#:P2RX2-144HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human P2RX2 Protein, MYC/DDK-tagged
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Cat.#:P2RX2-492HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human P2RX2
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Cat.#:P2RX2-4228RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat P2RX2 Protein
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Cat.#:P2RX2-9887ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish P2RX2
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Cat.#:P2RX2-3501HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human P2RX2 293 Cell Lysate
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Cat.#:CSC-RI0182Tag:
Source (Host):Species:Human
Product nameHuman P2RX2 Stable Cell Line-HEK293
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Cat.#:CSC-RI0183Tag:
Source (Host):Species:Human
Product nameHuman P2RX2 Stable Cell Line-HEK293
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Cat.#:CSC-RI0184Tag:
Source (Host):Species:Human
Product nameHuman P2RX2/P2RX3 Stable Cell Line-HEK293
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Cat.#:CSC-RI0185Tag:
Source (Host):Species:Human
Product nameHuman P2RX2/P2RX3 Stable Cell Line-HEK293
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Involved Pathway

P2RX2 involved in several pathways and played different roles in them. We selected most pathways P2RX2 participated on our site, such as Calcium signaling pathway, Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with P2RX2 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Calcium signaling pathway
ATP2B2; ITPR1; CAMK2G; ADRB3A; PPP3CA; CACNA1SA; CAMK4; PDGFRB; CACNA1H; ERBB3B
Neuroactive ligand-receptor interaction
LOC100328615; CHRNB3B; TBXA2R; NPFFR2.1; CHRM2A; NMUR2; PTH2R; TAAR6; P2RX4B; TSHB

Protein Function

P2RX2 has several biochemical functions, for example, ATP binding, cadmium ion binding, cobalt ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by P2RX2 itself. We selected most functions P2RX2 had, and list some proteins which have the same functions with P2RX2. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein STK16; UBE2T; PIP5K1A; HSPE1; ATP2A2A; UBE2Q1; CCT3; PRKD2; RUNX2; P2RX3
Function cadmium ion binding
Related Protein NOS1; MT3; P2RX2; SLC11A2; NOS3
Function cobalt ion binding
Related Protein NUDT16; PML; P2RX2; SLC11A2; BIRC5
Function copper ion binding
Related Protein RNF7; F5; P2RX2; SCO2; LOX; PAM; S100A13; SCO1; CCS; LOXL3
Function drug binding
Related Protein ADH1; TYMS; PYGL; PPP3CB; NR1I2; MTOR; HTR2A; FABP1; CNR1; DRD3
Function extracellular ATP-gated cation channel activity
Related Protein P2RX4; P2RX8; P2RX7; P2RX2; P2RX3A; NNR; P2RX3; P2RX6; P2RX5; P2RX4B
Function identical protein binding
Related Protein P2RX6; STK4; APLP1; ALK; PRDX1; C1QTNF9; TRIM21; TNF; INS2; PIP4K2C
Function ligand-gated ion channel activity
Related Protein CHRNA3; CHRNB2; CHRNB4; TRPA1A; CNGA3; CLCA2; ANXA6; GABRB1; P2RX2; ZACN
Function mercury ion binding
Related Protein PARK7; P2RX2
Function nickel cation binding
Related Protein P2RX2; CAR3; SLC11A2; CA3
Function phosphatidylinositol binding
Related Protein ARHGAP33; PIK3C2B; NISCH; MITD1; PASK; MTM1; SNX31; SNX18A; ING2; SNX12
Function purinergic nucleotide receptor activity
Related Protein P2RX4; NNR; P2RX3A; P2RX5; P2RX8; P2RX1; P2RX3; P2RX2; P2RX4A; P2RX7
Function zinc ion binding
Related Protein ZNF385D; GLO1; TRIM26; CDA; RBM4B; SERPINB1A; TOP3A; RERE; WBP2NL; KDM1B