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RGS13

Official Full Name

regulator of G-protein signaling 13
Overview

The protein encoded by this gene is a member of the regulator of G protein signaling (RGS) family. RGS family members share similarity with S. cerevisiae SST2 and C. elegans egl-10 proteins, which contain a characteristic conserved RGS domain. RGS proteins accelerate GTPase activity of G protein alpha-subunits, thereby driving G protein into their inactive GDP-bound form, thus negatively regulating G protein signaling. RGS proteins have been implicated in the fine tuning of a variety of cellular events in response to G protein-coupled receptor activation. The biological function of this gene, however, is unknown. Two transcript variants encoding the same isoform exist.
Synonyms

RGS13; regulator of G-protein signaling 13; regulator of G protein signalling 13; regulator of G-protein signalling 13; MGC17173;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	RGS13-2275H	Recombinant Human RGS13, GST-tagged	E.coli	GST	1-159aa	$319 / 25ug
Human	RGS13-688H	Recombinant Human RGS13 Protein, His-tagged	E.coli	His		Inquiry
Human	RGS13-2384HCL	Recombinant Human RGS13 293 Cell Lysate	HEK293	N/A		Inquiry
Mouse	Rgs13-5492M	Recombinant Mouse Rgs13 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Zebrafish	RGS13-5606Z	Recombinant Zebrafish RGS13	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
RGS13 Related Articles

RGS13 involved in several pathways and played different roles in them. We selected most pathways RGS13 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with RGS13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

RGS13 has several biochemical functions, for example, GTPase activator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RGS13 itself. We selected most functions RGS13 had, and list some proteins which have the same functions with RGS13. You can find most of the proteins on our site.

Function	Related Protein
GTPase activator activity	GIT2;ARHGAP10;LLGL2;SRGAP2;ALDH1A2;SIPA1L2;ACAP3B;PREX2;RGS13

RGS13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RGS13 here. Most of them are supplied by our site. Hope this information will be useful for your research of RGS13.

Wang, JH; New, JS; et al. Extension of the Germinal Center Stage of B Cell Development Promotes Autoantibodies in BXD2 Mice. ARTHRITIS AND RHEUMATISM 65:2703-2712(2013).

Pise-Masison, CA; Radonovich, M; et al. Gene expression profiling of ATL patients: compilation of disease-related genes and evidence for TCF4 involvement in BIRC5 gene expression and cell viability. BLOOD 113:4016-4026(2009).