tkt
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  • Official Full Name
  • transketolase
  • Background
  • This gene encodes a thiamine-dependent enzyme which plays a role in the channeling of excess sugar phosphates to glycolysis in the pentose phosphate pathway. Multiple alternatively spliced variants, encoding the same protein, have been identified.
  • Synonyms
  • TKT; transketolase; Wernicke Korsakoff syndrome; EC 2.2.1.1; FLJ34765; MS799; TK; TKT 1; TKT_HUMAN; TKT1; Transketolase (Wernicke Korsakoff syndrome); OTTHUMP00000212664; OTTHUMP00000212667; OTTHUMP00000212668
Cat.#:TKT-644HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TKT Protein, His-tagged
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Cat.#:Tkt-645RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Tkt Protein, His-tagged
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Cat.#:TKT-30354THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TKT, His-tagged
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Cat.#:TKT-3248HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TKT, GST-tagged
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Cat.#:TKT-16809MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse TKT Protein
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Cat.#:TKT-6081RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat TKT Protein
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Cat.#:TKT-4143BTag:His
Source (Host):E. coli or YeastSpecies:Bacillus subtilis
Product nameRecombinant Bacillus subtilis TKT protein, His-tagged
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Cat.#:TKT-1054HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human TKT 293 Cell Lysate
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Involved Pathway

TKT involved in several pathways and played different roles in them. We selected most pathways TKT participated on our site, such as Pentose phosphate pathway, Metabolic pathways, Carbon metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with TKT were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Pentose phosphate pathway
ALDOB; PFKP; FBP1A; ALDOCB; TALDO1; GPI1; GPI; PRPS1A; TKTL2; RBKS
Metabolic pathways
BST1; DAK; DHODH; STT3A; AMY2A4; GBGT1; ALG6; PIGH; AOX1; ACSL5
Carbon metabolism
AGXTA; HADHAB; ENO3; ENO1; GLUD1A; PRPS1; PRPS2; H6PD; PKM; PGAM2
Biosynthesis of amino acids
GPT2L; GPT2; TKTB; IDH3G; TALDO1; CBSB; PRPS2; GOT2B; GLULC; GPT

Protein Function

TKT has several biochemical functions, for example, cofactor binding, metal ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TKT itself. We selected most functions TKT had, and list some proteins which have the same functions with TKT. You can find most of the proteins on our site.
Function
Related Protein
Function cofactor binding
Related Protein UROS; C3; BIRC5; WWOX; HACL1; ASNS; HIF1AN; PHYH; LMO2; PAH
Function metal ion binding
Related Protein OGDH; PLA2G4AA; PPM1LB; NR1D4B; HBA-X; LMO4A; ZFP14; KARS; FIBCD1; PRIM1
Function protein binding
Related Protein PCGF3; PRKD2; B2M; C4orf33; RPL14; C4orf19; HDHD3; GAB2; DNAJB11; LSM11
Function protein homodimerization activity
Related Protein EVLA; HSP90AA1; SHMT1; HMOX1; PDZD7; VAPB; PAH; PVRL3; CHEK2; IKBKB
Function transketolase activity
Related Protein TKTL1; TKT; TKTB; TKTL2

Interacting Protein

TKT has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TKT here. Most of them are supplied by our site. Hope this information will be useful for your research of TKT.
TERF1; EIF1B; GH1; MCC; HLA-B; VHL; GABARAPL2; YWHAZ; IKBKE; FBXO11; Bles03; ACTR6; ATG5; Csnk1e; TNFRSF10D; FTSJ1; accC1; bglA; smtA3

TKT Related Articles

Hartmannsberger, D; Mack, B; et al. Transketolase-like protein 1 confers resistance to serum withdrawal in vitro. CANCER LETTERS 300:20-29(2011).
Mayer, A; von Wallbrunn, A; et al. Evidence against a Major Role for TKTL-1 in Hypoxic and Normoxic Cancer Cells. OXYGEN TRANSPORT TO TISSUE XXXII 701:123-128(2011).