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TKT

  • Official Full Name

    transketolase

  • Overview

    This gene encodes a thiamine-dependent enzyme which plays a role in the channeling of excess sugar phosphates to glycolysis in the pentose phosphate pathway. Multiple alternatively spliced variants, encoding the same protein, have been identified.
  • Synonyms

    TKT; transketolase; Wernicke Korsakoff syndrome; EC 2.2.1.1; FLJ34765; MS799; TK; TKT 1; TKT_HUMAN; TKT1; Transketolase (Wernicke Korsakoff syndrome); OTTHUMP00000212664; OTTHUMP00000212667; OTTHUMP00000212668;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Bacillus subtilis
  • Durum wheat
  • Human
  • Mouse
  • Rat
  • E. coli or Yeast
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Mammalian cells
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
  • N
  • No tag
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human TKT-30354TH Recombinant Human TKT, His-tagged E.coli His
Human TKT-3248H Recombinant Human TKT, GST-tagged E.coli GST C-term-350aa
Human TKT-1054HCL Recombinant Human TKT 293 Cell Lysate HEK293 N/A
Human TKT-2124HFL Recombinant Full Length Human TKT Protein, C-Flag-tagged Mammalian cells Flag
Human TKT-644H Recombinant Human TKT Protein, His-tagged E.coli His Met1~Pro294
Human TKT-2200H Recombinant Human TKT Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human TKT-2499H Recombinant Human TKT protein, His-tagged E.coli His 274-623 aa
Human TKT-2200H-B Recombinant Human TKT Protein Pre-coupled Magnetic Beads HEK293
Human TKT-5784H Recombinant Human TKT Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human TKT-6462H Recombinant Human TKT Protein (Met1-Pro294), His tagged E.coli His Met1-Pro294
Human TKT-3587H Recombinant Human TKT protein E.coli N/A 1-623aa
Human TKT-0284H Recombinant Human TKT Protein (E2-A623), His tagged E.coli His E2-A623
Human TKT-1322H Recombinant Human TKT Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human TKT-0285H Recombinant Human TKT Protein (E2-A623), Tag Free E.coli No tag E2-A623
Mouse TKT-16809M Recombinant Mouse TKT Protein Mammalian Cell His
Mouse Tkt-6444M Recombinant Mouse Tkt Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse TKT-9229M-B Recombinant Mouse TKT Protein Pre-coupled Magnetic Beads HEK293
Mouse TKT-9229M Recombinant Mouse TKT Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat TKT-6081R Recombinant Rat TKT Protein Mammalian Cell His
Rat TKT-5738R Recombinant Rat TKT Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat Tkt-645R Recombinant Rat Tkt Protein, His-tagged E.coli His Met1~Lys286
Rat TKT-5738R-B Recombinant Rat TKT Protein Pre-coupled Magnetic Beads HEK293
Bacillus subtilis TKT-4143B Recombinant Bacillus subtilis TKT protein, His-tagged E. coli or Yeast His
Durum wheat TKT-1475D Recombinant Durum wheat TKT Protein (Ser29-Ser586), N-His tagged E.coli N-His Ser29-Ser586
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • TKT Related Articles

TKT involved in several pathways and played different roles in them. We selected most pathways TKT participated on our site, such as Pentose phosphate pathway, Metabolic pathways, Carbon metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with TKT were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Pentose phosphate pathwayFBP1A;H6PD;ALDOCB;GPIA;ALDOAB;TALDO1;PGD;RPE;G6PD
Metabolic pathwaysSUCLG2;PMM1;CYP2P10;MTHFD1L;HYAL2;ATP6V1E1B;IMPDH2;PCYT1A;AK4
Carbon metabolismPDHB;DLST;ALDOA;MDH1AA;HK3;FH1;PGD;MDH2;PC
Biosynthesis of amino acidsARG2;BCAT1;CPS1;IDH1;ALDOCB;PFKMB;TKT;MTR;GPT2L

TKT has several biochemical functions, for example, cofactor binding, metal ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TKT itself. We selected most functions TKT had, and list some proteins which have the same functions with TKT. You can find most of the proteins on our site.

Function Related Protein
cofactor bindingPGAM2;DAO;ME3;ACLY;BIRC5;ACLYA;TKT;TYMS;LMO2
metal ion bindingITGAL;MBTD1;COL1A2;ACAN;AGFG1B;PSMD14;HSPG2;GNPTAB;ZFP326
protein bindingKIAA0368;HAX1;CCL28;VGLL4;RPS6;CENPA;ATG4A;DCX;COMMD6
protein homodimerization activityMUC13;WWTR1;PCYT1A;KLRB1B;TYRP1;IL17F;ENO3;TENM3;GPD1
transketolase activityTKTL2;TKT;TKTL1;TKTB

TKT has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TKT here. Most of them are supplied by our site. Hope this information will be useful for your research of TKT.

TERF1; EIF1B; GH1; MCC; HLA-B; VHL; GABARAPL2; YWHAZ; IKBKE; FBXO11; Bles03; ACTR6; ATG5; Csnk1e; TNFRSF10D; FTSJ1; accC1; bglA; smtA3

Hartmannsberger, D; Mack, B; et al. Transketolase-like protein 1 confers resistance to serum withdrawal in vitro. CANCER LETTERS 300:20-29(2011).
Mayer, A; von Wallbrunn, A; et al. Evidence against a Major Role for TKTL-1 in Hypoxic and Normoxic Cancer Cells. OXYGEN TRANSPORT TO TISSUE XXXII 701:123-128(2011).
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