ubn1
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  • Official Full Name
  • ubinuclein 1
  • Synonyms
  • UBN1; ubinuclein 1; ubinuclein-1; HIRA-binding protein; ubiquitously expressed nuclear protein; VT; VT4
Cat.#:UBN1-17751MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse UBN1 Protein
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Cat.#:UBN1-5078RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey UBN1 Protein, His-tagged
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Cat.#:UBN1-3551CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken UBN1
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Cat.#:UBN1-5993ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish UBN1
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Involved Pathway

UBN1 involved in several pathways and played different roles in them. We selected most pathways UBN1 participated on our site, such as Cellular Senescence, Cellular responses to stress, DNA Damage/Telomere Stress Induced Senescence, which may be useful for your reference. Also, other proteins which involved in the same pathway with UBN1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cellular Senescence
CDK4; AGO1; POT1A; CBX4; RBBP7; RNF2; LMNB1; BMI1A; EED; HIST1H1B
Cellular responses to stress
HMGA1B; CBX6; CDKN2D; MAPKAPK2B; CDKN2C; HSPA12B; EHMT2; TERF2; TXNRD2; CDKN2A
DNA Damage/Telomere Stress Induced Senescence
HMGA1B; TERF2IP; CABIN1; TERF2; HIST1H1A; TINF2; HMGA1-RS1; UBN1; RAD50; POT1
Formation of Senescence-Associated Heterochromatin Foci (SAHF)
HIST1H1C; EP400; ASF1A; UBN1; HMGA1B; HIST1H1A; HIST1H1E; HIRA; HIST1H1B; CABIN1

Protein Function

UBN1 has several biochemical functions, for example, DNA binding, transcription factor activity, sequence-specific DNA binding, transcription factor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by UBN1 itself. We selected most functions UBN1 had, and list some proteins which have the same functions with UBN1. You can find most of the proteins on our site.
Function
Related Protein
Function DNA binding
Related Protein DNA2; MYCL1; HDGF2; NR2F6B; ZNF18; HOXB8B; RUNX2B; JRKL; YBX2; PURG
Function transcription factor activity, sequence-specific DNA binding
Related Protein MAFGA; NR1H4; ZNF471; MYT1LA; TBX3A; TSC22D4; LHX8A; VDRB; EGR2A; DMRT1
Function transcription factor binding
Related Protein STK4; FIGLA; RBFOX2; TRIB2; PPP1R13BA; SMAD3; KCNA3; ATF7; FOXF2; GATA6

Interacting Protein

UBN1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UBN1 here. Most of them are supplied by our site. Hope this information will be useful for your research of UBN1.
Ywhae

UBN1 Related Articles

Pchelintsev, NA; McBryan, T; et al. Placing the HIRA Histone Chaperone Complex in the Chromatin Landscape. CELL REPORTS 3:1012-1019(2013).
Tang, Y; Puri, A; et al. Identification of an Ubinuclein 1 Region Required for Stability and Function of the Human HIRA/UBN1/CABIN1/ASF1a Histone H3.3 Chaperone Complex. BIOCHEMISTRY 51:2366-2377(2012).