Biotech Industry News And Bioscience News
European Found New Coronavirus and Infection
The picture shows images of coronavirus According to Reuters report, the Centers for Disease Control and Prevention (CDC) on Thursday (Mar. 7, 2013) warned U.S.A. and the local health officials about potential infections from a fatal virus that has affected fourteen people and caused the death
Scientists Found a New Solution to Boom Long-lasting Memory—Molecular mTORC2
If we want to remember something for a long time, we need to through a procedure in which the long-term memory starts with a short-term memory and consolidation, such as repetition, as least that is what older studies showed. Several days ago, some researchers found another solution, a critical
Nature Immunology: Target on Specific Point of Protein Bcl6
Recently in Nature Immunology, researchers declaimed that we might have chance to shut down Bcl6 in DLBCL, while not affecting its vital function in T cells and macrophages that are needed to support a healthy immune system. Diffuse large B-cell lymphoma (DLBCL), the seventhly commonly diagnosed
Blood: A New Immune “Rare Disease” Has Been Identified
Recently a paper on the Blood journal revealed that a research group found a new kind of B-cell defect, which stated that severe autoimmunity in childhood can be an indication of a primary immunodeficiency (PID). The result was gained on a 13-year-old patient with the novel genetic
Cell: Scientists Found another Role of Enzyme Superoxide Dismutase
Since 1960s, the initial discovery of Superoxide dismutase (SOD1), an enzyme that was believed having solo role in protecting living cells against damage from free radicals by scientists. The enzyme is present in all living cells, from the most ancient bacteria to every cell in the human body.
Cell: Researchers Found a Novel Rule of Membrane Proteins
Like the teeth of a zipper, the charged amino acids (as the red and blue color show) form connections between protein segments and thus form pores in the cell membrane. Membrane proteins, attached to or associated with the membrane of a cell or an organelle, perform a variety of functions
Science: Studies Revealed a New Innate Immunity Sensor of Enzyme and Cell Signaling Pathway
Scientists have known the immune-boosting response of DNA for a long time, but the specific mechanism of the underlying response is unknown. The studies solved the longstanding puzzle by means of a special biochemical approach. The approach is quantitative mass spectrometry which adopts a
The Combination of Genome-wide and Proteome-wide Screening
In clinical application or research purpose, plasma screening has been widely used due to its easy accessibility, so as mass spectrometry. Nowadays, gene variants are easy to identify, however theses phenotypes that link to those variants are not easy. Using mass spectrometry, researchers
Protein Bax: Reveal One Potential Mechanism of Cell Death
The left picture shows the main researchers of this finding; the right picture shows the visualization of the molecular changes in protein Bax Cell death, or apoptosis, is an important factor in controlling the number of cells in the body. Proper cell numbers ensure our health condition; over
Nature: No Haploid Phase in Candida Albicans
Candida albicans is a diploid fungus that grows both as yeast and filamentous cells. It is also a causal agent of opportunistic oral and genital infections in humans. It has high mortality with 45 percent and is one of the four main microbial pathogens in hospital acquired infections. However,
PANS: The Key Role of Mthfd1l for Folic Acid and Neural Tube
In 1940s, Mthfd1l was found. It is an enzyme encoded by Mthfd1l gene in human that involves in THF synthesis in mitochondria. It has been known for long time that certain variants of Mthfd1l are associated neural tube defects. Weeks ago Proceedings of the National Academy of Sciences (PNAS)
Nature: How OTUD7B Saves TRAF3
TRAF3, TNF receptor-associated factor 3, is a protein that in humans is encoded by the TRAF3 gene. TRAF3 belongs to the TNFR family member which is important for the activation of the immune response. TNFR3 is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling
Cell Biology: The Importance of PEFs in Cell Mitosis
The picture shows the expression of the chromokinesin NOD (red) stabilizes aberrant interactions between kinetochores and spindle microtubules (green). Cell division helps to maintain the even distribution genome of two daughter cells in which every chromosome need to properly interact with
Protein Structure: Researchers Found How Viral Protein Suppresses Immune Protein
The innate immune system, the first line of defense against pathogens and noxious chemicals, detects invasive pathogens and activates defense mechanisms to eliminate them. The defense system is made up of an array of receptors that are in charge of recognizing specific molecular conformations of
Cell: A Promising Trend That Avoids Foreign Rejection and Replaces Damaged Neurons on self
This is a confocal micrograph of a primary human fibroblast cell grown in culture stained blue for actin, a highly abundant protein that makes up the cytoskeleton of cells. Mitochondria are shown in green. According to some statistics, it is estimated that 25% Americans will suffer from a
IFIT Protein: Its Molecular Mechanism on Distinguishing Viral RNA only
IFIT protein, an anti-virus protein, allows the human immune system to detect viruses and prevent infection. It services as foot soldiers guarding the body against infection. It recognizes foreign viral ribonucleic acid (RNA) produced by the virus and acts as defender molecules by potentially
Part of Proprietary Technology Platforms of Creative BioMart
With innovative thoughts and fast growing technologies, Creative BioMart experts have developed many efficient and advanced proprietary technical platforms that have gained numerous praises. As a biotech manufacture, its goal is to mutually benefit research communities, institutions and others.
Food Poison: Cellular Toxicity Caused By Nhe Was First Revealed in a Doctoral Thesis
Recently a doctoral research revealed a protein structure of how Bacillus cereus causes toxin. The author is Danh Phung, he found the crystalline structure of NheA. Phung's study is the first to show that the Nhe proteins form structures resembling pores. We know that food poisoning caused by
Nature: The Link between Inhibiting NLRP3 and Decreasing Alzheimer's
According to a research led by Eicke Latz, MD from the University of Bonn in Germany, inhibiting a protein complex dubbed NLRP3 might slow the progression of Alzheimer's disease. People have known that the protein complex plays a role in inflammation, but it’s not clear if it contributes to
The Chromosome Structure of a RNA Antitoxin Complex and Its Altruistic Mechanism
A new research reveals how some bacterial cells keep a 'suicide complex' ready to hand. In the journal Proceedings of the National Academy of Sciences, you will find an article which talks about some bacterial cells carry a molecular 'suicide complex' to kill themselves in the event of
Use a More Cheap with Equal Effect Paper-based Diagnostic Method to Test Whether You Are Pregnant, Have Diabetes, Malaria etc.?
You could find the new finding on the American Chemical Society journal Langmuir. The new advance in diagnostics research was conducted by University of Washington bioengineer Daniel Ratner and his team. Now we already can do home based tests for some conditions, such as for pregnancy, diabetes,
Nature: Study Led by NIH Depicted the Specific Description of Brain Protein Structure
Researchers from National Institute of Neurological Disorders and Stroke (NINDS) have published the first highly detailed description of how a neuropeptide hormone, neurotensin, which been previously shown has correlation to Parkinson’s disease, schizophrenia, temperature regulation, pain,
microRNA is an Important Factor That Propels How We Become a Human
The Picture Shows the Differentiating Mouse Embryonic Stem Cells (green = mesoderm progenitor cells, red = endoderm progenitor cells). Our human organism is initially starts form an embryo which from one cell to an entire living and breathing body, full of working cells and organs. We never
One of the 54th ASH Annual Meeting Presentations: SGEN' Antibody-drug Conjugate Hit a Hope for the Treatment of AML
This year as usual on the 54th American Society of Hematology (ASH) annual meeting, there were lot of new findings and explorations were presented and shared. One of them, the Seattle Genetics ($SGEN) gave a brief presentations on SGN-CD33A, which is one of its early-stage next-generation
PLoS Biology: Prehistoric Yeast DNA Study Unveil the Controversial Point of Theory of Evolution
There once was a hit topic assumed that might we could clone dinosaur by the fossil they left, on one hand to explored the evolvement history, on the other hand to take back the pre-history amazing animals though later scientist confirmed that the half-decay period of DNA is 521 years, which