alg9
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  • Official Full Name
  • asparagine-linked glycosylation 9, alpha-1,2-mannosyltransferase homolog
  • Background
  • This gene encodes an alpha-1,2-mannosyltransferase enzyme that functions in lipid-linked oligosaccharide assembly. Mutations in this gene result in congenital disorder of glycosylation type Il. Multiple transcript variants encoding different isoforms have been found for this gene.
  • Synonyms
  • ALG9; asparagine-linked glycosylation 9, alpha-1,2-mannosyltransferase homolog (S. cerevisiae); asparagine linked glycosylation 9 homolog (yeast, alpha 1,2 mannosyltransferase) , asparagine linked glycosylation 9, alpha 1,2 mannosyltransferase homolog (
Cat.#:ALG9-468HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ALG9 Protein, GST-tagged
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Cat.#:ALG9-1551MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse ALG9 Protein
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Cat.#:ALG9-10898ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish ALG9
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Cat.#:ALG9-8904HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human ALG9 293 Cell Lysate
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Involved Pathway

ALG9 involved in several pathways and played different roles in them. We selected most pathways ALG9 participated on our site, such as N-Glycan biosynthesis, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with ALG9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
N-Glycan biosynthesis
ALG9; TUSC3; ALG8; MGAT5; MAN1A1; ALG13; DOLK; ALG12; STT3B; ST6GAL2A
Metabolic pathways
ATP6V1B2; UGT8A; HYAL3; GBE1; POLR2K; AKR1C3; HSD3B1; FUT8A; POLR1A; ATP6V1C2

Protein Function

ALG9 has several biochemical functions, for example, dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity, dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity, mannosyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ALG9 itself. We selected most functions ALG9 had, and list some proteins which have the same functions with ALG9. You can find most of the proteins on our site.
Function
Related Protein
Function dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity
Related Protein ALG9; ZNF408
Function dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity
Related Protein ZNF408; ALG9
Function mannosyltransferase activity
Related Protein GALNT18A; B3GNT9-PS; GALNTL4; GLT8D1; PIGV; ALG1; UGGT1; DPY19L1L; PIGZ; ALG12

Interacting Protein

ALG9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ALG9 here. Most of them are supplied by our site. Hope this information will be useful for your research of ALG9.
flhA; BHMT

ALG9 Related Articles

Coss, KP; Treacy, EP; et al. Systemic gene dysregulation in classical Galactosaemia: Is there a central mechanism?. MOLECULAR GENETICS AND METABOLISM 113:177-187(2014).
Barone, R; Fiumara, A; et al. Congenital Disorders of Glycosylation with Emphasis on Cerebellar Involvement. SEMINARS IN NEUROLOGY 34:357-366(2014).