Recombinant Human ALG9 Protein, GST-tagged
Cat.No. : | ALG9-468H |
Product Overview : | Human ALG9 full-length ORF ( NP_079016.1, 1 a.a. - 618 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes an alpha-1,2-mannosyltransferase enzyme that functions in lipid-linked oligosaccharide assembly. Mutations in this gene result in congenital disorder of glycosylation type Il. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 97.2 kDa |
AA Sequence : | MASRGARQRLKGSGASSGDTAPAAD KLRELLGSREAGGAEHRTELSGNKA GQVWAPEGSTAFKCLLSARLCAALL SNISDCDETFNYWEPTHYLIYGEGF QTWEYSPAYAIRSYAYLLLHAWPAA FHARILQTNKILVFYFLRCLLAFVS CICELYFYKAVCKKFGLHVSRMMLA FLVLSTGMFCSSSAFLPSSFCMYTT LIAMTGWYMDKTSIAVLGVAAGAIL GWPFSAALGLPIAFDLLVMKHRWKS FFHWSLMALILFLVPVVVIDSYYYG KLVIAPLNIVLYNIFTPHGPDLYGT EPWYFYLINGFLNFNVAFALALLVL PLTSLMEYLLQRFHVQNLGHPYWLT LAPMYIWFIIFFIQPHKEERFLFPV YPLICLCGAVALSALQHSFLYFQKC YHFVFQRYRLEHYTVTSNWLALGTV FLFGLLSFSRSVALFRGYHGPLDLY PEFYRIATDPTIHTVPEGRPVNVCV GKEWYRFPSSFLLPDNWQLQFIPSE FRGQLPKPFAEGPLATRIVPTDMND QNLEEPSRYIDISKCHYLVDLDTMR ETPREPKYSSNKEEWISLAYRPFLD ASRSSKLLRAFYVPFLSDQYTVYVN YTILKPRKAKQIRKKSGG |
Applications : | Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | ALG9 asparagine-linked glycosylation 9, alpha-1,2-mannosyltransferase homolog (S. cerevisiae) [ Homo sapiens ] |
Official Symbol : | ALG9 |
Synonyms : | ALG9; asparagine-linked glycosylation 9, alpha-1,2-mannosyltransferase homolog (S. cerevisiae); asparagine linked glycosylation 9 homolog (yeast, alpha 1,2 mannosyltransferase) , asparagine linked glycosylation 9, alpha 1,2 mannosyltransferase homolog (S. cerevisiae, alpha 1,2 mannosyltransferase) , DIBD1, disrupted in bipolar affective disorder 1; alpha-1,2-mannosyltransferase ALG9; disrupted in bipolar disorder protein 1; disrupted in bipolar affective disorder 1; asparagine-linked glycosylation protein 9 homolog; dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase; dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase; loss of heterozygosity, 11, chromosomal region 1 gene J product; asparagine-linked glycosylation 9 homolog (yeast, alpha- 1,2-mannosyltransferase); asparagine-linked glycosylation 9 homolog (S. cerevisiae, alpha- 1,2-mannosyltransferase); CDG1L; DIBD1; LOH11CR1J; FLJ21845; DKFZp586M2420; |
Gene ID : | 79796 |
mRNA Refseq : | NM_024740 |
Protein Refseq : | NP_079016 |
MIM : | 606941 |
UniProt ID : | Q9H6U8 |
Products Types
◆ Recombinant Protein | ||
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ALG9-1551M | Recombinant Mouse ALG9 Protein | +Inquiry |
ALG9-3812H | Recombinant Human ALG9 protein, His-tagged | +Inquiry |
◆ Lysates | ||
ALG9-8904HCL | Recombinant Human ALG9 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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- Q&As
- Reviews
Q&As (17)
Ask a questionALG9 participates in the glycosylation of polypeptide chains through n-glycosylation transfer, and regulates the selectivity of n-glycosylation.
ALG9 is involved in the glycosylation of pectin synthetase and plays an important role in pectin biosynthesis.
ALG9 is involved in the modification of glycosylase of insulin precursor protein, and has a certain influence on the assembly and secretion of glycosylated insulin precursor protein.
Transcription and regulation of ALG9 are regulated by nucleic acid and protein interactions.
The glycosylation position of ALG9 is mainly involved in N-biglycosylation transfer.
ALG9 may be involved in many signaling pathways, such as glucose metabolism and endogenous antioxidant pathways.
ALG9 is related to other ALG family transferases, such as ALG3 and ALG12, which are involved in the control of protein n-glycosylation.
This is not only present in cell wall and cell membrane, but also widely expressed in underground organs and young leaves.
The high expression of ALG9 is associated with the occurrence of hypertension, obesity and other diseases.
It is mainly located in the endoplasmic reticulum and is involved in N-glycosylation.
Absence of ALG9 may be associated with congenital N-glycosylation disorder.
This is a membrane protein that contains a mini-domain on the cell membrane, a peptide expression regulation region and an N-terminal extension region.
The protein is involved in protein glycosylation and is related to the occurrence and development of some malignant tumors.
This protein is expressed in a variety of tissues and organs, such as the liver, the nervous system can be found in ALG9
The expression pattern of ALG9 protein is affected by many factors, including the regulation of transcription factors and external stimuli.
The structure and function of ALG9 are directly related, including the active site of the enzyme, the binding of the transfer substrate, etc., which are related to the glycosylation reaction of the polypeptide chain.
ALG9 is involved in many physiological processes, such as protein glycosylation, cell recognition, etc., and then affect the growth and development of the body and immune response.
Customer Reviews (4)
Write a reviewIt has made significant research progress in the application of related fields.
Low immunogenicity and does not cause abnormal immune responses.
ALG9 has good DNA binding ability and performs well in related experiments.
The structural integrity of ALG9 was verified, and the folding state and secondary structure were consistent with the native protein.
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