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Recombinant Human ALG9 Protein, GST-tagged

Cat.No. : ALG9-468H
Product Overview : Human ALG9 full-length ORF ( NP_079016.1, 1 a.a. - 618 a.a.) recombinant protein with GST-tag at N-terminal.
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  • Gene Information
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Description : This gene encodes an alpha-1,2-mannosyltransferase enzyme that functions in lipid-linked oligosaccharide assembly. Mutations in this gene result in congenital disorder of glycosylation type Il. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 97.2 kDa
AA Sequence : MASRGARQRLKGSGASSGDTAPAAD KLRELLGSREAGGAEHRTELSGNKA GQVWAPEGSTAFKCLLSARLCAALL SNISDCDETFNYWEPTHYLIYGEGF QTWEYSPAYAIRSYAYLLLHAWPAA FHARILQTNKILVFYFLRCLLAFVS CICELYFYKAVCKKFGLHVSRMMLA FLVLSTGMFCSSSAFLPSSFCMYTT LIAMTGWYMDKTSIAVLGVAAGAIL GWPFSAALGLPIAFDLLVMKHRWKS FFHWSLMALILFLVPVVVIDSYYYG KLVIAPLNIVLYNIFTPHGPDLYGT EPWYFYLINGFLNFNVAFALALLVL PLTSLMEYLLQRFHVQNLGHPYWLT LAPMYIWFIIFFIQPHKEERFLFPV YPLICLCGAVALSALQHSFLYFQKC YHFVFQRYRLEHYTVTSNWLALGTV FLFGLLSFSRSVALFRGYHGPLDLY PEFYRIATDPTIHTVPEGRPVNVCV GKEWYRFPSSFLLPDNWQLQFIPSE FRGQLPKPFAEGPLATRIVPTDMND QNLEEPSRYIDISKCHYLVDLDTMR ETPREPKYSSNKEEWISLAYRPFLD ASRSSKLLRAFYVPFLSDQYTVYVN YTILKPRKAKQIRKKSGG
Applications : Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : ALG9 asparagine-linked glycosylation 9, alpha-1,2-mannosyltransferase homolog (S. cerevisiae) [ Homo sapiens ]
Official Symbol : ALG9
Synonyms : ALG9; asparagine-linked glycosylation 9, alpha-1,2-mannosyltransferase homolog (S. cerevisiae); asparagine linked glycosylation 9 homolog (yeast, alpha 1,2 mannosyltransferase) , asparagine linked glycosylation 9, alpha 1,2 mannosyltransferase homolog (S. cerevisiae, alpha 1,2 mannosyltransferase) , DIBD1, disrupted in bipolar affective disorder 1; alpha-1,2-mannosyltransferase ALG9; disrupted in bipolar disorder protein 1; disrupted in bipolar affective disorder 1; asparagine-linked glycosylation protein 9 homolog; dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase; dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase; loss of heterozygosity, 11, chromosomal region 1 gene J product; asparagine-linked glycosylation 9 homolog (yeast, alpha- 1,2-mannosyltransferase); asparagine-linked glycosylation 9 homolog (S. cerevisiae, alpha- 1,2-mannosyltransferase); CDG1L; DIBD1; LOH11CR1J; FLJ21845; DKFZp586M2420;
Gene ID : 79796
mRNA Refseq : NM_024740
Protein Refseq : NP_079016
MIM : 606941
UniProt ID : Q9H6U8

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (17)

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How does ALG9 participate in the regulation of N-glycosylation? 03/05/2023

ALG9 participates in the glycosylation of polypeptide chains through n-glycosylation transfer, and regulates the selectivity of n-glycosylation.

What is the effect of ALG9 on pectin synthesis? 01/27/2023

ALG9 is involved in the glycosylation of pectin synthetase and plays an important role in pectin biosynthesis.

What role does ALG9 play in glycosylation of insulin? 09/03/2022

ALG9 is involved in the modification of glycosylase of insulin precursor protein, and has a certain influence on the assembly and secretion of glycosylated insulin precursor protein.

What is the transcription mechanism of ALG9? 07/29/2022

Transcription and regulation of ALG9 are regulated by nucleic acid and protein interactions.

Where is the glycosylation position of ALG9? 07/06/2021

The glycosylation position of ALG9 is mainly involved in N-biglycosylation transfer.

What signaling pathways are involved in ALG9? 06/21/2021

ALG9 may be involved in many signaling pathways, such as glucose metabolism and endogenous antioxidant pathways.

Which enzymes do ALG9 have in common? 10/26/2020

ALG9 is related to other ALG family transferases, such as ALG3 and ALG12, which are involved in the control of protein n-glycosylation.

What is the expression pattern and distribution of ALG9 in plants? 09/05/2020

This is not only present in cell wall and cell membrane, but also widely expressed in underground organs and young leaves.

What diseases are correlated with the high expression of ALG9? 06/23/2020

The high expression of ALG9 is associated with the occurrence of hypertension, obesity and other diseases.

What is the location of ALG9 in the cell? 06/19/2020

It is mainly located in the endoplasmic reticulum and is involved in N-glycosylation.

What diseases is ALG9 loss associated with? 05/04/2020

Absence of ALG9 may be associated with congenital N-glycosylation disorder.

What are the structural characteristics of ALG9? 03/14/2020

This is a membrane protein that contains a mini-domain on the cell membrane, a peptide expression regulation region and an N-terminal extension region.

Does the association between ALG9 and tumor? 10/30/2019

The protein is involved in protein glycosylation and is related to the occurrence and development of some malignant tumors.

In which tissues is ALG9 expressed? 10/13/2019

This protein is expressed in a variety of tissues and organs, such as the liver, the nervous system can be found in ALG9

Does the expression pattern of ALG9? 08/09/2019

The expression pattern of ALG9 protein is affected by many factors, including the regulation of transcription factors and external stimuli.

How the relationship between the structure and function of ALG9? 08/03/2019

The structure and function of ALG9 are directly related, including the active site of the enzyme, the binding of the transfer substrate, etc., which are related to the glycosylation reaction of the polypeptide chain.

What physiological processes does ALG9 participate in? 07/30/2019

ALG9 is involved in many physiological processes, such as protein glycosylation, cell recognition, etc., and then affect the growth and development of the body and immune response.

Customer Reviews (4)

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Reviews
03/30/2022

    It has made significant research progress in the application of related fields.

    10/13/2021

      Low immunogenicity and does not cause abnormal immune responses.

      09/02/2021

        ALG9 has good DNA binding ability and performs well in related experiments.

        05/12/2020

          The structural integrity of ALG9 was verified, and the folding state and secondary structure were consistent with the native protein.

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