ALPK1
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Official Full Name
alpha-kinase 1
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Overview
Unlike most eukaryotic kinases, alpha kinases, such as LAK, recognize phosphorylation sites in which the surrounding peptides have an alpha-helical conformation. -
Synonyms
ALPK1; alpha-kinase 1; alpha-protein kinase 1; FLJ22670; KIAA1527; Lak; lymphocyte alpha kinase; 8430410J10Rik; Alpha protein kinase 1; Chromosome 4 kinase; Lymphocyte alpha protein kinase; RGD1304613; lymphocyte alpha-kinase; lymphocyte alpha-protein kinase;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- E.coli
- HEK293
- HEK293T
- Insect Cell
- Mammalian cells
- Wheat Germ
- C
- Myc
- DDK
- Flag
- GST
- His
- His (Fc)
- Avi
- N/A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | ALPK1-491H | Recombinant Human ALPK1 Protein, GST-tagged | Wheat Germ | GST |
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| Human | ALPK1-8894HCL | Recombinant Human ALPK1 293 Cell Lysate | HEK293 | N/A |
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| Human | ALPK1-394HFL | Recombinant Full Length Human ALPK1 Protein, C-Flag-tagged | Mammalian cells | Flag |
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| Human | ALPK1-2177H | Recombinant Human ALPK1 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Myc/DDK |
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| Human | ALPK1-5985H | Recombinant Human ALPK1 protein, His&Myc-tagged | Insect Cell | His&Myc | 1017-1237aa |
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| Human | ALPK1-001H | Recombinant Human ALPK1 Protein, Myc/DDK-tagged | HEK293T | C-Myc/DDK |
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| Human | ALPK1-327H-B | Recombinant Human ALPK1 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Human | ALPK1-327H | Recombinant Human ALPK1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Human | ALPK1-3097H | Recombinant Human ALPK1 protein, His-tagged | E.coli | His | 1-347 aa | |
| Mouse | Alpk1-1605M | Recombinant Mouse Alpk1 Protein, Myc/DDK-tagged | HEK293T | Myc/DDK |
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- Involved Pathway
- Protein Function
- Interacting Protein
- ALPK1 Related Articles
ALPK1 involved in several pathways and played different roles in them. We selected most pathways ALPK1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ALPK1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
ALPK1 has several biochemical functions, for example, ATP binding, protein serine/threonine kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ALPK1 itself. We selected most functions ALPK1 had, and list some proteins which have the same functions with ALPK1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | MARS2;PI4K2A;SRPK2;ZNF143B;UBE2Z;NME2A;PRPF4BA;AK2;ACSM1 |
| protein serine/threonine kinase activity | MINK1;NEK7;MOK;CSNK1A1L;SQSTM1;RPS6KA3B;NEK6;MYLK4;MKNK1 |
ALPK1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ALPK1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ALPK1.
HSP90AB1
- Q&As
- Reviews
Q&As (10)
Ask a questionYes, ALPK1 kinase activity can be modulated by specific small molecule inhibitors that target its ATP-binding site.
ALPK1 influences intracellular signaling cascades such as MAPK and AKT pathways and can modulate the expression of specific target genes.
ALPK1 knockout or overexpression can lead to altered cell morphology, proliferation rates, and cell cycle progression.
ALPK1 is primarily localized in the cytoplasm of human cells.
ALPK1 has been associated with both pro-apoptotic and anti-apoptotic signaling pathways, suggesting a complex role in cellular survival.
Yes, the expression of ALPK1 can be upregulated or downregulated in response to various stress stimuli.
ALPK1 is implicated in promoting cellular proliferation and growth.
ALPK1 has been implicated in regulating cellular migration and invasion in certain cell types.
Phosphorylation is a known post-translational modification that can regulate ALPK1 activity.
Several interacting proteins and signaling pathways have been identified, including protein kinases, phosphatases, and cytoskeletal regulators.
Customer Reviews (3)
Write a reviewHighly effective fusion protein detection.
Exceptional protein-protein interaction analysis.
Specific target detection in immunohistochemistry.
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