arih2
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  • Official Full Name
  • ariadne homolog 2
  • Background
  • Protein ariadne-2 homolog is a protein that in humans is encoded by the ARIH2 gene.
  • Synonyms
  • ARIH2; ariadne homolog 2 (Drosophila); ariadne (Drosophila) homolog 2; E3 ubiquitin-protein ligase ARIH2; all trans retinoic acid inducible RING finger; TRIAD1; ARI-2; protein ariadne-2 homolog; all-trans retinoic acid inducible RING finger; ARI2; FLJ1093
Cat.#:ARIH2-800HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ARIH2 protein, GST-tagged
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Cat.#:ARIH2-4250CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken ARIH2
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Cat.#:ARIH2-12359ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish ARIH2
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Cat.#:ARIH2-8725HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human ARIH2 293 Cell Lysate
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Involved Pathway

ARIH2 involved in several pathways and played different roles in them. We selected most pathways ARIH2 participated on our site, such as Adaptive Immune System, Antigen processing: Ubiquitination &, Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with ARIH2 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Adaptive Immune System
RAPGEF3; LAIR1; CTSB; ITPR2; Siglece; ICAM4; TREML2; KIF20A; CYBA; KIF2B
Antigen processing: Ubiquitination &
FBXO27; UBE2L6; LRRC41; RNF6; UBE2U; PJA1; HUWE1; NPEPPS; TRIM9; RNF25
Proteasome degradation
HUWE1; HECTD3; RNF182; KLHL20; UBE2L6; ASB17; UBE2E3; RNF41; IWS1; UBE2F
Class I MHC mediated antigen processing &
ASB4; UBR1; RNF144B; LRR1; RNF14; ERAP1; ERAP2; RNF19B; RNF4; RBCK1
presentation
ASB6; ASB3; SPSB1; UBE2V2; TRIM50; LRSAM1; KLHL20; TRIM9; UFL1; RNF19B
Immune System
IFI35; MYO1C; SIGLEC7; DEFB104A; ABI1; RAET1E; MB21D1; CSH1; KIFAP3; TRIM48

Protein Function

ARIH2 has several biochemical functions, for example, ligase activity, nucleic acid binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ARIH2 itself. We selected most functions ARIH2 had, and list some proteins which have the same functions with ARIH2. You can find most of the proteins on our site.
Function
Related Protein
Function ligase activity
Related Protein HECTD1; TNFAIP3; RNF25; NEDD4; TRAF7; TRIM41; RNF144AB; CMTM2A; UBR3; TRIM24
Function nucleic acid binding
Related Protein ZFP521; KLF14; SF3B6; ERI2; ZFP74; SNAI1B; ZXDC; ZFPM1; ZFP536; PRDM7
Function protein binding
Related Protein KXD1; PEX10; RRAS2; APBB1IP; KLF15; HSPA4L; HPSE; SHOX; GRIN2C; RECQL
Function ubiquitin conjugating enzyme binding
Related Protein ANKIB1; ANKIB1A; DCUN1D4; SIAH2; RNF14; DCUN1D2; TCHP; RNF180; MARCH6; TRIM72
Function ubiquitin protein ligase activity
Related Protein SIAH1; RAD18; UBR1; HECTD1; ARIH1; ITCHA; UBR2; C12orf51; RABGEF1; PDZRN4
Function ubiquitin-protein transferase activity
Related Protein MIB2; HECW1B; MGRN1; PRP19; SIAH2L; MDM2; RNF144B; RNF187; BIRC3; RNF182
Function zinc ion binding
Related Protein DPEP1; MTA1; ZNF34; RNF168; SAMHD1; GCH1; BTR30; TRIM2A; RBM20; MMP13

Interacting Protein

ARIH2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARIH2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ARIH2.
UBE2L3; UBE2L6; TP53