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Official Full Name ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
Background This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c, c, and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is known as the D subunit and is found ubiquitously.
Synonyms ATP6V0D1; ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1; ATP6D, ATPase, H+ transporting, lysosomal (vacuolar proton pump), member D , ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d isoform 1 , ATPase, H+ transporting, lysosomal 38kDa,
    • Species :
    • Chicken
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • MYC/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse Atp6v0d1-672M Recombinant Mouse Atp6v0d1 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Human ATP6V0D1-10037H Recombinant Human ATP, His-tagged E.coli His
    Human ATP6V0D1-8588HCL Recombinant Human ATP6V0D1 293 Cell Lysate HEK293 N/A
    Human ATP6V0D1-997H Recombinant Human ATP6V0D1 protein, GST-tagged Wheat Germ GST
    Mouse ATP6V0D1-2154M Recombinant Mouse ATP6V0D1 Protein Mammalian Cell His
    Chicken ATP6V0D1-5584C Recombinant Chicken ATP6V0D1 Mammalian Cell His
    Zebrafish ATP6V0D1-10021Z Recombinant Zebrafish ATP6V0D1 Mammalian Cell His

    ATP6V0D1 involved in several pathways and played different roles in them. We selected most pathways ATP6V0D1 participated on our site, such as Oxidative phosphorylation, Metabolic pathways, Lysosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATP6V0D1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Oxidative phosphorylation NDUFB2; NDUFV1; ATP6V0A1B; ATP6V1C1; SDHD; ATP5G1; ATP5J; SDHC; ATP6V1F; ATP4B
    Metabolic pathways C1GALT1B; GALNT11; ZNF408; ATP5A1; PTGES3A; POLE3; CYP21A2; PAH; GLCEB; GALNT1
    Lysosome MAN2B1; SLC11A1; AP4E1; IDS; CTSO; SMPD1; ATP6V0C; PSAP; AP1M3; GALC
    Phagosome HLA-DQA1; ATP6V1C1A; BMA2; ATP6V1H; C3A.2; MHC2A; OLR1; TLR4BA; MSR1; CD209
    Synaptic vesicle cycle ATP6V1E2; ATP6V1B2; ATP6V0B; SLC17A6; ATP6V0E1; SLC17A8; CPLX4; CPLX2; ATP6V0E2; ATP6V0C
    Collecting duct acid secretion SLC12A7; ATP6V1B2; ATP6V1A; ATP6V0E2; ATP6V0E; ATP6V1E1; CLCNKB; ATP6V0C; ATP6V1C2; ATP6V1G3
    Vibrio cholerae infection ATP6V1A; SEC61G; ATP6V1E1; ATP6V1C2; ATP6V1D; ATP6V1F; KDELR3; ATP6V1G2; ATP6V0D1; ATP6V1B1
    Epithelial cell signaling in Helicobacter pylori infection RAC1; NFKBIA; ATP6V1H; ATP6V1G1; ATP6V1E2; ADAM17; TCIRG1; ATP6V0D2; ATP6V0A4; ATP6V0D1
    Tuberculosis RFX5; IFNA13; CD209A; HLA-DOA; APAF1; HLA-DQA1; IFNA1; EEA1; ATP6V0B; IL10RB
    Viral carcinogenesis PIK3CA; GTF2H2C; CCND1; MAPK1; HIST1H2BK; PSMC1; C3; HPN; HDAC7; MAD1L1
    Rheumatoid arthritis ATP6V1B2; IL1A; TNFSF13B; CCL3L1; IL23; CTLA4; H2-AB1; ITGB2; CXCL12; H2-AA

    ATP6V0D1 has several biochemical functions, for example, hydrogen-exporting ATPase activity, phosphorylative mechanism, protein binding, protein complex binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ATP6V0D1 itself. We selected most functions ATP6V0D1 had, and list some proteins which have the same functions with ATP6V0D1. You can find most of the proteins on our site.

    Function Related Protein
    hydrogen-exporting ATPase activity, phosphorylative mechanism ATP6V1C2; ATP6V1G1; ATP6V0D1; ATP6V1C1; ATP6V1G3; ATP6V1E1; ATP6V1E2
    protein binding GLE1; MS4A3; CD84; TRAPPC3; IL2RB; GTPBP3; FKBP1B; TEK; KHDC3; ABCC2
    protein complex binding CDH2; ABI1; CDK2; TRAF2; SLC27A5; WASF1; RAD18; MYSM1; BCAP31; ATF1

    ATP6V0D1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATP6V0D1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ATP6V0D1.

    ATXN1; pi3p; Ccdc9; ATP6AP2; A2M; CDK1; PTPN1; Rab5c; Bmpr1a; TMPO; Vps4b; RAB5C; RAB7A; RAB2A; Cbx1; CLTC; Rmdn3; TMEM63B; Ptpn23; RFWD3

    Pacheco-Costa, R; Hassan, I; et al. High Bone Mass in Mice Lacking Cx37 Because of Defective Osteoclast Differentiation. JOURNAL OF BIOLOGICAL CHEMISTRY 289:8508-8520(2014).
    Chung, JY; Yi, JW; et al. Changes in Gene Expression in the Rat Hippocampus after Focal Cerebral Ischemia. JOURNAL OF KOREAN NEUROSURGICAL SOCIETY 50:173-178(2011).

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