fut2
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  • Official Full Name
  • fucosyltransferase 2 (secretor status included)
  • Background
  • The protein encoded by this gene is a Golgi stack membrane protein that is involved in the creation of a precursor of the H antigen, which is required for the final step in the soluble A and B antigen synthesis pathway. This gene is one of two encoding the galactoside 2-L-fucosyltransferase enzyme. Two transcript variants encoding the same protein have been found for this gene.
  • Synonyms
  • FUT2; fucosyltransferase 2 (secretor status included); SE; galactoside 2-alpha-L-fucosyltransferase 2; alpha (1; 2) fucosyltransferase; alpha(1; 2)FT2; galactoside 2 alpha L fucosyltransferase 2; GDP L fucose:beta D galactoside 2 alpha L fucosyltransferase 2; Se2; SEC2; secretor blood group alpha 2 fucosyltransferase; secretor factor; sej; Fucosyltransferase 2; alpha(1,2)FT2; alpha(1,2)FT 2; OTTHUMP00000226681; OTTHUMP00000226682; alpha (1,2) fucosyltransferase; secretor blood group alpha-2-fucosyltransferase; GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosylt; B12QTL1
Cat.#:FUT2-4559HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human FUT2 Protein, GST-tagged
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Cat.#:FUT2-2414RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat FUT2 Protein
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Cat.#:FUT2-6115HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human FUT2 293 Cell Lysate
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Involved Pathway

FUT2 involved in several pathways and played different roles in them. We selected most pathways FUT2 participated on our site, such as Glycosphingolipid biosynthesis - lacto and neolacto series, Glycosphingolipid biosynthesis - globo series, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with FUT2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Glycosphingolipid biosynthesis - lacto and neolacto series
ST3GAL3; B4GALT4; B3GALT1; FUT9A; B3GNTL2; B3GNT5A; FUT2; GCNT2; B4GALT2; FUT7
Glycosphingolipid biosynthesis - globo series
A4GALT; FUT9A; FUT2; GBGT1; GLA; HEXA; B3GALT5; FUT1; GBGT1L4; B3GALNT1
Metabolic pathways
PIK3C2B; FPGT; TPI1B; CCBL2; ST6GALNAC6; GAD1B; UGT2A1; PANK4; NDUFB11; AK7B

Protein Function

FUT2 has several biochemical functions, for example, fucosyltransferase activity, galactoside 2-alpha-L-fucosyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by FUT2 itself. We selected most functions FUT2 had, and list some proteins which have the same functions with FUT2. You can find most of the proteins on our site.
Function
Related Protein
Function fucosyltransferase activity
Related Protein DPY19L4; FT2; UGGT1; B3GNT9-PS; FUT2; POC1BL; FUT3; B3GNTL1; GTDC2; FUT7
Function galactoside 2-alpha-L-fucosyltransferase activity
Related Protein FUT1; FUT2

Interacting Protein

FUT2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FUT2 here. Most of them are supplied by our site. Hope this information will be useful for your research of FUT2.
ZDHHC17

FUT2 Related Articles

Friedrich, M; Diegelmann, J; et al. IL-17A Alone Weakly Affects the Transcriptome of Intestinal Epithelial Cells but Strongly Modulates the TNF-alpha-induced Expression of Inflammatory Mediators and Inflammatory Bowel Disease Susceptibility Genes. INFLAMMATORY BOWEL DISEASES 20:1502-1515(2014).
Khodayar-Pardo, P; Martinez-Costa, C; et al. Norovirus GII.4 Antibodies in Breast Milk and Serum Samples Their Role Preventing Virus-Like Particles Binding to Their Receptors. PEDIATRIC INFECTIOUS DISEASE JOURNAL 33:554-559(2014).