GSR
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Official Full Name
glutathione reductase
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Overview
This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Aug 2010] -
Synonyms
GSR; glutathione reductase; HEL-75; glutathione reductase, mitochondrial; GR; GRase; epididymis luminal protein 75;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- Zebrafish
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- His|T7
- Myc
- DDK
- MYC
- Myc|DDK
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- GSR Related Articles
- GSR Related Research Area
GSR involved in several pathways and played different roles in them. We selected most pathways GSR participated on our site, such as Glutathione metabolism, Thyroid hormone synthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with GSR were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Glutathione metabolism | GSTT2;GCLC;RRM2B;ANPEPB;GGT6;GSTM7;MGST3;GPX4A;GGT5A |
| Thyroid hormone synthesis | ATP1A3;CANX;CREB5;PLCB1;PLCB2;PRKCA;TPO;ATP1B4;GPX7 |
GSR has several biochemical functions, for example, NADP binding, electron carrier activity, flavin adenine dinucleotide binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GSR itself. We selected most functions GSR had, and list some proteins which have the same functions with GSR. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| NADP binding | NOS3;NOX5;ASPDH;GSR;FMO1;DPYD;PGD;NDOR1;G6PDX |
| electron carrier activity | COX7A1;GCDH;NDUFS6;AOX3L1;AKR1B1;GLDC;DHRS3;ETFB;AKR7A3 |
| flavin adenine dinucleotide binding | KDM1B;DUS4L;AIFM4;DUS3L;ACAD8;NOS1;ACADM;DLD;ACOX1 |
| glutathione-disulfide reductase activity |
GSR has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GSR here. Most of them are supplied by our site. Hope this information will be useful for your research of GSR.
RB1; rhtB3; PJA1; C11orf49
- Q&As
- Reviews
Customer Reviews (3)
Write a reviewThe GSR protein is an exceptional tool for investigating the intricate mechanisms and pathogenesis of amyloid-related diseases.
Their collaboration during trial design and data analysis enhances the reliability and significance of my research findings.
The GSR protein's exceptional quality, coupled with the manufacturer's outstanding technical support, ensures that it fulfills my experimental needs with utmost precision and efficacy.
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