| Description : |
This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
56.3 kDa |
| AA Sequence : |
MALLPRALSAGAGPSWRRAARAFRG FLLLLPEPAALTRALSRAMACRQEP QPQGPPPAAGAVASYDYLVIGGGSG GLASARRAAELGARAAVVESHKLGG TCVNVGCVPKKVMWNTAVHSEFMHD HADYGFPSCEGKFNWRVIKEKRDAY VSRLNAIYQNNLTKSHIEIIRGHAA FTSDPKPTIEVSGKKYTAPHILIAT GGMPSTPHESQIPGASLGITSDGFF QLEELPGRSVIVGAGYIAVEMAGIL SALGSKTSLMIRHDKVLRSFDSMIS TNCTEELENAGVEVLKFSQVKEVKK TLSGLEVSMVTAVPGRLPVMTMIPD VDCLLWAIGRVPNTKDLSLNKLGIQ TDDKGHIIVDEFQNTNVKGIYAVGD VCGKALLTPVAIAAGRKLAHRLFEY KEDSKLDYNNIPTVVFSHPPIGTVG LTEDEAIHKYGIENVKTYSTSFTPM YHAVTKRKTKCVMKMVCANKEEKVV GIHMQGLGCDEMLQGFAVAVKMGAT KADFDNTVAIHPTSSEELVTLRTRT RPLEQKLISEEDLAANDILDYKDDD DKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
